Zobrazeno 1 - 10
of 697
pro vyhledávání: '"Jean-Pierre Changeux"'
Autor:
Sophie Shi, Solène N. Lefebvre, Laurie Peverini, Adrien H. Cerdan, Paula Milán Rodríguez, Marc Gielen, Jean-Pierre Changeux, Marco Cecchini, Pierre-Jean Corringer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Glycine receptors are channel receptors mediating signal transduction between neurons that transit between resting and open states upon neurotransmitter binding. Here, the authors illuminate a progressive transition of opening by combining voltage-cl
Externí odkaz:
https://doaj.org/article/2f309521f60544c4a944d621a652fe13
Publikováno v:
Network Neuroscience, Vol 6, Iss 4, Pp 950-959 (2022)
AbstractWhat structural and connectivity features of the human brain help to explain the extraordinary human cognitive abilities? We recently proposed a set of relevant connectomic fundamentals, some of which arise from the size scaling of the human
Externí odkaz:
https://doaj.org/article/aa3172eec6224a2aa61453f15080ffc9
Autor:
Guilherme Dias deMelo, Françoise Lazarini, Florence Larrous, Lena Feige, Etienne Kornobis, Sylvain Levallois, Agnès Marchio, Lauriane Kergoat, David Hardy, Thomas Cokelaer, Pascal Pineau, Marc Lecuit, Pierre‐Marie Lledo, Jean‐Pierre Changeux, Hervé Bourhy
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 8, Pp n/a-n/a (2021)
Abstract The devastating pandemic due to SARS‐CoV‐2 and the emergence of antigenic variants that jeopardize the efficacy of current vaccines create an urgent need for a comprehensive understanding of the pathophysiology of COVID‐19, including t
Externí odkaz:
https://doaj.org/article/b938603666f241f49eacf1f691b585e8
Autor:
Olivier Chosidow, Charlotte Bernigaud, Didier Guillemot, Bruno Giraudeau, Anne Lespine, Jean-Pierre Changeux, Hervé Bourhy, Marc Lecuit, Zahir Amoura
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009446 (2021)
Externí odkaz:
https://doaj.org/article/4d90369e899c41f4b6fbcd602a2c33f6
Publikováno v:
Frontiers in Systems Neuroscience, Vol 14 (2020)
The electrophysiology of the paralimbic network (“default mode”) for self-awareness has drawn much attention in the past couple of decades. In contrast, knowledge of the molecular organization of conscious experience has only lately come into foc
Externí odkaz:
https://doaj.org/article/40d323911db34557836e9f28f3d05e46
Publikováno v:
Ciencias Sociales y Educación, Vol 5, Iss 10, Pp 201-220 (2016)
Tomado de Michel Morange, Francis Wolff y Frédéric Worms (dirs.). El hombre neuronal, treinta años después. Diálogo con Jean-Pierre Changeux. París: Rue d’Ulm/Presses de l’École normale supérieure, 2016. pp. 121-143. Traducción del franc
Externí odkaz:
https://doaj.org/article/f11dcaaba549471cab778ec28e40d800
Publikováno v:
Ciencias Sociales y Educación, Vol 5, Iss 10, Pp 221-225 (2016)
Entrevista de Jean-François Dortier a Jean-Pierre Changeux Tomado de Jean-François Dortier (dir.). El cerebro y el pensamiento. La nueva edad de las ciencias cognitivas. Auxerre: Sciences Humaines éditions, 2014 ‹ed. revisada y aumentada del
Externí odkaz:
https://doaj.org/article/97ac9d84a1944fbcb570fc93d6188b04
Publikováno v:
Frontiers in Psychiatry, Vol 9 (2018)
In the present paper, we suggest a potential new ethical analysis of addiction focusing on the relationship between aware and unaware processing in the brain. We take the case of the opioids epidemics to argue that a consideration of both aware and u
Externí odkaz:
https://doaj.org/article/78087a1551ca4806ae955e83d933ec6c
Autor:
Jean-Pierre Changeux
Publikováno v:
Biomolecules, Vol 10, Iss 4, p 547 (2020)
The concept of pharmacological receptor was proposed at the turn of the 20th century but it took almost 70 years before the first receptor for a neurotransmitter was isolated and identified as a protein. This review retraces the history of the diffic
Externí odkaz:
https://doaj.org/article/4939a5b919e04ed2aface38d658d7b4f
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 10, p e1005784 (2017)
Pentameric ligand-gated ion channels (pLGICs) mediate intercellular communication at synapses through the opening of an ion pore in response to the binding of a neurotransmitter. Despite the increasing availability of high-resolution structures of pL
Externí odkaz:
https://doaj.org/article/4bae105208bc469c98e7d204bf509deb