Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jean-Pierre Cabaniols"'
Autor:
Christophe Perez, Valérie Guyot, Jean-Pierre Cabaniols, Agnès Gouble, Beatrice Micheaux, Julie Smith, Sophie Leduc, Frédéric Pâques, Philippe Duchateau
Publikováno v:
BioTechniques, Vol 39, Iss 1, Pp 109-115 (2005)
Double-strand break (DSB)-induced homologous recombination (HR) of direct repeats is a powerful means to achieve gene excision, a critical step in genome engineering. In this report we have used an extrachromosomal reporter system to monitor the impa
Externí odkaz:
https://doaj.org/article/1580e8c8425a4d9fae731c0d79632b5f
Autor:
Fabien Delacôte, Christophe Perez, Valérie Guyot, Catherine Mikonio, Pierrick Potrel, Jean-Pierre Cabaniols, Christophe Delenda, Frédéric Pâques, Philippe Duchateau
Publikováno v:
Journal of Nucleic Acids, Vol 2011 (2011)
Homologous gene targeting (HGT) is a precise but inefficient process for genome engineering. Several methods for increasing its efficiency have been developed, including the use of rare cutting endonucleases. However, there is still room for improvem
Externí odkaz:
https://doaj.org/article/e61488346f9f4760adf94a2ded8d2de9
Autor:
Fayza Daboussi, Séverine Thomas, Alexandre Juillerat, Jean-Pierre Cabaniols, Céline Lebuhotel, Annabelle Gariboldi, Julien Valton, Fabien Delacôte, Sebastien Paris, Adeline Jacquet, Sandra Rolland, Domique Alain Blanchard, Marianne Duhamel, Gil Letort, Sandra Moriceau, Raffy Demirdjian, Aymeric Duclert, Roman Galetto, Philippe Duchateau, Claudia Bertonati
Publikováno v:
Methods. 69:151-170
TALEN is one of the most widely used tools in the field of genome editing. It enables gene integration and gene inactivation in a highly efficient and specific fashion. Although very attractive, the apparent simplicity and high success rate of TALEN
Autor:
Christophe Perez, Sylvia Bruneau, Julianne Smith, Laurence Fiette, Patrick Ave, Béatrice Micheau, Frédéric Pâques, Jean-Pierre Cabaniols, Valérie Guyot, Philippe Duchateau, Sophie Leduc, Agnès Gouble
Publikováno v:
The Journal of Gene Medicine. 8:616-622
Background Sequence-specific endonucleases with large recognition sites can cleave DNA in living cells, and, as a consequence, stimulate homologous recombination (HR) up to 10 000-fold. The recent development of artificial meganucleases with chosen s
Autor:
Frédéric Pâques, Philippe Duchateau, Julie Smith, Jean-Pierre Cabaniols, Beatrice Micheaux, Sophie Leduc, Agnès Gouble, Valérie Guyot, Christophe Perez
Publikováno v:
BioTechniques. 39:109-115
Double-strand break (DSB)-induced homologous recombination (HR) of direct repeats is a powerful means to achieve gene excision, a critical step in genome engineering. In this report we have used an extrachromosomal reporter system to monitor the impa
Autor:
N. Fazilleau, Jean-Pierre Cabaniols, Armanda Casrouge, Philippe Kourilsky, Jean Kanellopoulos
Publikováno v:
Pathologie Biologie. 50:151-156
Autor:
Jean-Pierre Cabaniols, Armanda Casrouge, Jean M. Kanellopoulos, Nicolas Fazilleau, Philippe Kourilsky
Publikováno v:
The Journal of Experimental Medicine
The contribution of template-independent nucleotide addition to antigen receptor diversity is unknown. We therefore determined the size of the T cell receptor (TCR)alpha/beta repertoire in mice bearing a null mutation on both alleles of the terminal
Publikováno v:
Journal of Biological Chemistry. 275:2959-2965
The docking and fusion of synaptic vesicles with the presynaptic plasma membrane require the interaction of the vesicle-associated membrane protein VAMP with the plasma membrane proteins syntaxin and SNAP-25. Both of these proteins behave as integral
Publikováno v:
Biochemical Journal. 338:709-715
SNARE proteins are required for vesicle docking and fusion in eukaryotic cells in processes as diverse as homotypic membrane fusion and synaptic vesicle exocytosis [SNARE stands for SNAP receptor, where SNAP is soluble NSF attachment protein]. The SN
Autor:
Laurent Gapin, Yolanda Bravo de Alba, Armanda Casrouge, Jean Pierre Cabaniols, Philippe Kourilsky, Jean Kanellopoulos
Publikováno v:
The Journal of Immunology. 160:1555-1564
T lymphocyte responses to a protein Ag are restricted to a limited number of determinants and not to all peptides capable of binding to MHC class II molecules. This focusing of the immune response is defined as immunodominance and has been observed w