Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jean-Pierre Bidouard"'
Autor:
Clara Dees, Philip Janiak, Bertrand Léger, Christian Beyer, Alfiya Distler, Josef Pernerstorfer, Jean Pierre Bidouard, Laetitia Ledein, Serena Vettori, Stephane Illiano, Rachid Boukaiba, Jörg H W Distler, Oliver Distler, Matthias Schaefer, Hartmut Ruetten, Alexandre Jagerschmidt
Publikováno v:
British Journal of Pharmacology
Background and purpose Genetic deletion and pharmacological studies suggest a role for lysophosphatidic acid (LPA1 ) receptor in fibrosis. We investigated the therapeutic potential in systemic sclerosis (SSc) of a new orally active selective LPA1 rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3461709fb9e09a11345ee3c0c728b42c
https://doi.org/10.1111/bph.15190
https://doi.org/10.1111/bph.15190
Autor:
Jean-Pierre Bidouard, Fabrice Barbe, Bruno Poirier, Philippe Beauverger, Philip Janiak, Frédéric Petit, Paul J. Schaeffer, Marie-Laure Ozoux, Michel Pelat, Véronique Briand, Jean-Michel Guillon, Jean-Michel Altenburger
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 374:24-37
Chronic kidney disease (CKD) remains a common disorder, leading to growing health and economic burden without curative treatment. In diabetic patients, CKD may result from a combination of metabolic and nonmetabolic-related factors, with mortality ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::263ed2eef8f17107cfac3577e5dfc46c
https://doi.org/10.1124/jpet.120.265496
https://doi.org/10.1124/jpet.120.265496
Autor:
Bruno, Poirier, Veronique, Briand, Dieter, Kadereit, Matthias, Schäfer, Paulus, Wohlfart, Marie-Claire, Philippo, Dominique, Caillaud, Laurent, Gouraud, Patrick, Grailhe, Jean-Pierre, Bidouard, Marc, Trellu, Anthony J, Muslin, Philip, Janiak, Ashfaq A, Parkar
Publikováno v:
Science signaling. 13(634)
Endothelial dysfunction is a hallmark of tissue injury and is believed to initiate the development of vascular diseases. Sphingosine-1 phosphate receptor-1 (S1P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7f8a8b0518c71c8c58ecee8e043691eb
https://pubmed.ncbi.nlm.nih.gov/32487716
https://pubmed.ncbi.nlm.nih.gov/32487716
Autor:
Philip Janiak, Dieter Kadereit, Marie-Claire Philippo, Laurent Gouraud, Anthony J. Muslin, Dominique Caillaud, Paulus Wohlfart, Jean-Pierre Bidouard, Véronique Briand, Bruno Poirier, Ashfaq Parkar, Marc Trellu, Patrick Grailhe, Matthias Schäfer
Publikováno v:
Science Signaling. 13
Endothelial dysfunction is a hallmark of tissue injury and is believed to initiate the development of vascular diseases. Sphingosine-1 phosphate receptor-1 (S1P1) plays fundamental physiological roles in endothelial function and lymphocyte homing. Cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6a8bf60e17d484becdb54212c81c05d
https://doi.org/10.1126/scisignal.aax8050
https://doi.org/10.1126/scisignal.aax8050
Publikováno v:
Journal of Cardiovascular Pharmacology. 42:688-696
The effects of ivabradine, a novel heart rate-reducing agent that inhibits the cardiac pacemaker current If, were compared with those of the beta-adrenergic blocker propranolol, in a model of exercise-induced regional myocardial ischemia in pigs. Fiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f849254d38d9660c671ed43de2b4fc6d
https://doi.org/10.1097/00005344-200311000-00016
https://doi.org/10.1097/00005344-200311000-00016
Autor:
Etienne Gautier, Fabrice Barbe, Jean-Pierre Bidouard, Stephen E. O'Connor, Alain Grosset, Philip Janiak
Publikováno v:
European Journal of Pharmacology. 474:117-120
We have studied the ability of SL65.0472 (7-fluoro-2-oxo-4-[2-[4-(thieno[3,2-c]pyridin-4-yl)piperazin-1-yl]ethyl]-1,2-dihydroquinoline-1-acetamide), a 5-hydroxytryptamine (5-HT) 5-HT1B/5-HT2A receptor antagonist, to antagonise the vasoconstrictor eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d2fbca40ed5f99caeb72873b063ebac
https://doi.org/10.1016/s0014-2999(03)02032-6
https://doi.org/10.1016/s0014-2999(03)02032-6
Autor:
Jean-Paul Vilaine, Jean-Pierre Bidouard, Olivier Malo, Nicole Villeneuve, Louis P. Perrault, Paul M. Vanhoutte
Publikováno v:
The Journal of Heart and Lung Transplantation. 22:439-451
The endothelium protects the vascular wall through the nitric oxide (NO) release. Coronary endothelial dysfunction occurs early after heart transplantation and predicts the development of intimal thickening typical of graft coronary vasculopathy.We d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42bec5bd14bc0a148017a19d4df31596
https://doi.org/10.1016/s1053-2498(02)00494-1
https://doi.org/10.1016/s1053-2498(02)00494-1
Autor:
Jean-Baptiste Michel, Jean-Marc Herbert, Philip Janiak, Jean-Pierre Bidouard, Charles-Edouard Luyt, Pierre Lainée, Yoann Grataloup, S. E. O'Connor
Publikováno v:
Cardiovascular Research. 56:293-302
Objective: Lower limb perfusion following arterial occlusion depends on the recruitment of collateral vessels. Blood flow through these collateral vessels may be jeopardized by hypersensitivity to vasoconstriction by serotonin (5-HT), as has been rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e456cf5977df7a2f644b9973c60100
https://doi.org/10.1016/s0008-6363(02)00538-2
https://doi.org/10.1016/s0008-6363(02)00538-2
Autor:
Jean-Paul Vilaine, Paul M. Vanhoutte, Nicole Villeneuve, Louis P. Perrault, Jean-Pierre Bidouard, Nathalie Desjardins
Publikováno v:
Transplantation. 74:764-772
BACKGROUND The nonworking heterotopic heart transplantation model has been used extensively for the study of rejection and coronary endothelial function in different species. The effect of left ventricular loading in a working heart transplantation m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff68eee2e79d01e6c1be14a8289a5184
https://doi.org/10.1097/00007890-200209270-00006
https://doi.org/10.1097/00007890-200209270-00006
Autor:
Matthieu Lévi-Strauss, Saoussen Karray, Catherine Beauvais, Jean-Pierre Bidouard, Philip Janiak, Cristina Gonzalez, Henri-Jean Garchon, Josiane Ménissier de Murcia
Publikováno v:
Diabetes
Diabetes, American Diabetes Association, 2002, 51 (5), pp.1470-1476. ⟨10.2337/diabetes.51.5.1470⟩
Diabetes, American Diabetes Association, 2002, 51 (5), pp.1470-1476. ⟨10.2337/diabetes.51.5.1470⟩
Poly(ADP-ribose) polymerase-1 (PARP-1) is a nuclear enzyme that consumes NAD in response to DNA strand breaks. Its excessive activation seems particularly deleterious to pancreatic β-cells, as exemplified by the complete resistance of PARP-1-deficie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61d455ed217ec96d21c666809ca8c235
https://doi.org/10.2337/diabetes.51.5.1470
https://doi.org/10.2337/diabetes.51.5.1470