Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Jean-Pierre Bégué"'
La chimie du fluor est devenue un secteur important de la chimie médicinale. Depuis la découverte du fluorouracile, des fluorocorticoïdes et des fluoroquinolones, ce jeune domaine a connu de rapides et d'importants progrès durant ces quinze derni
Publikováno v:
Organic Letters. 7:5219-5222
[reaction: see text] New artemisinin-derived dimers, fluorinated or not, have been prepared by a self-cross metathesis reaction in the presence of first- or second-generation ruthenium catalysts without degradation of the endoperoxide bridge and with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a82ba2b7215b5e162778b105d4ba9b
https://doi.org/10.1021/ol052056+
https://doi.org/10.1021/ol052056+
Autor:
Benoit Crousse, Danièle Bonnet-Delpon, Jean-Pierre Bégué, Guillaume Magueur, Nguyen Thi Ngoc Tam, Michèle Ourévitch
Publikováno v:
The Journal of Organic Chemistry. 70:699-702
The synthesis of the title compound is described through original and tailored synthetic protocols. The addition of vinylmagnesium bromide to CF(3)-N-aryl and N-alkyl aldimines was efficient and did not require an activating N-substituent. The result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9a8568c85ce2a414385f8be7300ff4
https://doi.org/10.1021/jo0485233
https://doi.org/10.1021/jo0485233
Publikováno v:
Handbook of Fluorous Chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::668c5fc18a9c9bfd9d455cfccd72ebd7
https://doi.org/10.1002/3527603905.ch10q
https://doi.org/10.1002/3527603905.ch10q
Publikováno v:
Scopus-Elsevier
Owing to their unique properties (high hydrogen bonding donor ability, low nucleophilicity, high ionizing power and ability to solvate water), fluorinated alcohols, hexafluoroisopropanol (HFIP) and trifluoroethanol (TFE),modify the course of reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5efc4fa9d30ffbdcca7445516aad2fa
https://doi.org/10.1055/s-2003-44973
https://doi.org/10.1055/s-2003-44973
Autor:
Thouraya Barhoumi-Slimi, Danièle Bonnet-Delpon, Benoit Crousse, Moncef El Gaied, Jean-Pierre Bégué, Michèle Ourévitch
Publikováno v:
Journal of Fluorine Chemistry. 117:137-141
The selective reduction of the trifluoro analog of the Hagemann’s ester 1 provided corresponding cyclohexenols, which underwent a Johnson–Claisen rearrangement leading to diesters 3. These latter are precursors of tetrahydroisochromanes 5 and oct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed389e16fc071317a2189322e3784914
https://doi.org/10.1016/s0022-1139(02)00153-7
https://doi.org/10.1016/s0022-1139(02)00153-7
Publikováno v:
Tetrahedron. 58:3993-3998
Comparative studies on mediated epoxidation reaction using Oxone® as primary oxidant and various fluoroketones as reagents, revealed that ketone 3 is very efficient, in particular when used in hexafluoroisopropanol (HFIP) as solvent. It does not suf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb68a813889ad16695fd16453e0f741c
https://doi.org/10.1016/s0040-4020(02)00252-1
https://doi.org/10.1016/s0040-4020(02)00252-1
Publikováno v:
Tetrahedron. 58:4067-4070
Reactivity and stability of trifluoromethylcyclohexane (TFMC) has been investigated towards various reagents, in order to evaluate its possible use as solvent. TFMC is stable in most oxidizing conditions, indicating the protective effect of a fluoroa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9918f46461acd53045bda0193afd8c1f
https://doi.org/10.1016/s0040-4020(02)00255-7
https://doi.org/10.1016/s0040-4020(02)00255-7
Autor:
Fatima Chorki, Fabienne Grellepois, Benoit Crousse, Michèle Ourévitch, Danièle Bonnet-Delpon, Jean-Pierre Bégué
Publikováno v:
The Journal of Organic Chemistry. 66:7858-7863
The reactions of the ring-contracted aldehydes, derived from anhydrodihydroartemisinin, with gem-difluoroenoxysilanes in the presence of BF(3).Et(2)O afforded the corresponding difluoromethylene ketol adducts in good yields. Similar Lewis acid cataly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d73d6b0be102c60d80b277d9c3e0d3
https://doi.org/10.1021/jo0158579
https://doi.org/10.1021/jo0158579
Publikováno v:
Tetrahedron Letters. 42:4463-4466
The fluoroalkylketone 2 is an efficient catalyst in the epoxidation reaction using Oxone® as oxidant. In hexafluoro-2-isopropanol (HFIP), the ketone can be used in a catalytic amount (1 or 5 mol%) with only 1.5 equiv. of Oxone®. The reaction gave g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecc297cdda817bc1e05449501224b090
https://doi.org/10.1016/s0040-4039(01)00751-1
https://doi.org/10.1016/s0040-4039(01)00751-1