Výsledky vyhledávání - "Jean-Pierre Bonvalet"

Exploring the role of galectin 3 in kidney function: a genetic approach

Autor: Dennis Brown, Maurice Bichara, Michel Peuchmaur, Marie Essig, Laetitia Micheli, Françoise Cluzeaud, Zoubida Karim, Isabelle Eude-Le Parco, Françoise Poirier, Amel Attmane-Elakeb, Martine Muffat-Joly, Nicolette Farman, Jean-Pierre Bonvalet

Publikováno v: Glycobiology. 16:36-45

Galectin 3 belongs to a family of glycoconjugate-binding proteins that participate in cellular homeostasis by modulating cell growth, adhesion, and signaling. We studied adult galectin 3 null mutant (Gal 3-/-) and wild-type (WT) mice to gain insights

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15846bcc747d8cd6fc3f177c672a995d
https://doi.org/10.1093/glycob/cwj035

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Impaired 11-β Hydroxysteroid Dehydrogenase Type 2 Activity in Sweat Gland Ducts in Human Essential Hypertension

Autor: Michel Hubert Capron, Jean Fiet, Martine Muffat-Joly, Sabine Kenouch, Nicolette Farman, Maxime Lamarre-Cliche, Brigitte Bocchi, Michel Azizi, Jean Pierre Bonvalet, Gilles Morineau

Publikováno v: Hypertension. 43:803-808

The enzyme 11-β hydroxysteroid dehydrogenase type 2 plays a major role in blood pressure regulation. It metabolizes glucocorticoid hormones into derivatives with low affinity for the mineralocorticoid receptor, preventing its permanent occupancy by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d01148e44ac2ff579cca2501a1b5c6a
https://doi.org/10.1161/01.hyp.0000121362.64182.ad

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Basolateral Translocation by Vasopressin of the Aldosterone-Induced Pool of Latent Na-K-ATPases Is Accompanied by α1 Subunit Dephosphorylation

Autor: Nathalie Courtois-Coutry, Marcel Blot-Chabaud, Say Viengchareun, Nicolette Farman, Michel Fay, Ahmed T. Beggah, Sabri Djelidi, Françoise Cluzeaud, Jean-Pierre Bonvalet

Publikováno v: Scopus-Elsevier

The regulation of plasma membrane Na + -K + -ATPases (NKA) expression by aldosterone and arginin vasopressin (AVP) in the cortical collecting duct (CCD) has been examined in a new rat CCD cell line, designated as RCCD 2 . This cell line has maintaine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e67f09390866b5f62fc3b1227d9154f5
https://doi.org/10.1681/asn.v1291805

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Tissue-Specific Expression of α and β Messenger Ribonucleic Acid Isoforms of the Human Mineralocorticoid Receptor in Normal and Pathological States

Autor: Maria-Christina Zennaro, Marc Lombès, Jean-Pierre Bonvalet, Nicolette Farman

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 82:1345-1352

Expression of the mineralocorticoid receptor (MR) is restricted to some sodium-transporting epithelia and a few nonepithelial target tissues. Determination of the genomic structure of the human MR (hMR) revealed two different untranslated exons (1alp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6871465699591cada6022f90f31226d3
https://doi.org/10.1210/jcem.82.5.3933

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Noncoordinated expression of alpha-, beta-, and gamma-subunit mRNAs of epithelial Na+ channel along rat respiratory tract

Autor: Michel Fay, C. Canessa, R. Boucher, C. R. Talbot, B. Rossier, Jean-Pierre Bonvalet, Nicolette Farman

Publikováno v: American Journal of Physiology-Cell Physiology. 272:C131-C141

Na+ reabsorption from the epithelial surface of the respiratory tract plays a fundamental role in respiratory physiology. As in the epithelia of the renal collecting tubule and distal colon, Na+ enters across the luminal surface of respiratory epithe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b2c1e371002204def3b37965cfcbf4
https://doi.org/10.1152/ajpcell.1997.272.1.c131

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Differential regulation of putative K(+)-ATPase by low-K+ diet and corticosteroids in rat distal colon and kidney

Autor: Brigitte Escoubet, Emmanuel Eugène, N. Coutry, Nicolette Farman, Jean-Pierre Bonvalet, Frederic Jaisser

Publikováno v: American Journal of Physiology-Cell Physiology
American Journal of Physiology-Cell Physiology, American Physiological Society, 1996, 270 (2), pp.C679-C687. ⟨10.1152/ajpcell.1996.270.2.C679⟩

K+ homeostasis depends on K+ absorption in digestive and renal epithelia. Recently, a cDNA encoding for a putative K(+)-adenosinetriphosphatase (ATPase) alpha-subunit has been characterized. We studied its expression by ribonuclease protection assay

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd30b2b4e52c832a9a65848c8aea188
https://doi.org/10.1152/ajpcell.1996.270.2.c679

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Differential expression of epithelial sodium channel subunit mRNAs in rat skin

Autor: A. Rochat, Emmanuel Eugène, C. Roudier-Pujol, Nicolette Farman, Jean-Pierre Bonvalet, Brigitte Escoubet, Y. Barrandon

Publikováno v: Journal of Cell Science. 109:379-385

Three subunits (alpha, beta, gamma) of the amiloride-sensitive epithelial sodium channel have been recently characterized. The channel subunits have significant homologies with the Caenorhabditis elegans mec-4, mec-10 and deg-1 genes, which are invol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62625d6a130ffade3db50e8885fb22e8
https://doi.org/10.1242/jcs.109.2.379

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Prerequisite for Cardiac Aldosterone Action

Autor: Nicolette Farman, Nadia Alfaidy, Jean-Pierre Bonvalet, Emmanuel Eugène, Marc Lombès, Alessandro Lessana

Publikováno v: Circulation. 92:175-182

Background It has been proposed that aldosterone exerts direct effects on heart function, most notably on the development of myocardial fibrosis during ventricular hypertrophy in rat. Initial events in aldosterone action entail its binding to mineral

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f2bbb1e30816164593308ebcd7a1bd
https://doi.org/10.1161/01.cir.92.2.175

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Human skin as target for aldosterone: coexpression of mineralocorticoid receptors and 11 beta-hydroxysteroid dehydrogenase

Autor: Marc Lombès, Francine Delahaye, Sabine Kenouch, Jean-Pierre Bonvalet, Nicolette Farman, Emmanuel Eugène

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 79:1334-1341

The expression of mineralocorticoid receptors (MR) and 11 beta-hydroxysteroid dehydrogenase (11HSD) activity has been investigated in the epidermis and appendages of the human skin. Aldosterone binds to MR and regulates sodium transport in tight epit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac80f3a4be9a55df79a6218f1cf38ed
https://doi.org/10.1210/jcem.79.5.7962326

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Aldosterone selectively increases Na(+)-K(+)-ATPase alpha 3-subunit mRNA expression in rat hippocampus

Autor: Jonathan Seckl, Jean-Pierre Bonvalet, Nicolette Farman

Publikováno v: American Journal of Physiology-Cell Physiology. 266:C423-C428

In the brain, corticosteroids bind to intracellular glucocorticoid (GR) and mineralocorticoid (MR) receptors, affecting target gene transcription, and thereby altering neuronal function, including electrophysiological activity. The hippocampus very h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3025804ce56f5d18bbf7b68edccba6
https://doi.org/10.1152/ajpcell.1994.266.2.c423

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