Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jean-Philippe Sinnes"'
Autor:
Jean-Philippe Sinnes, Ulrike Bauder-Wüst, Martin Schäfer, Euy Sung Moon, Klaus Kopka, Frank Rösch
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 5, Iss 1, Pp 1-11 (2020)
Abstract Background The AAZTA chelator and in particular its bifunctional derivative AAZTA5 was recently investigated to demonstrate unique capabilities to complex diagnostic and therapeutic trivalent radiometals under mild conditions. This study pre
Externí odkaz:
https://doaj.org/article/d1a2d3b0fd9c4b479ae97266b454021c
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 4, Iss 1, Pp 1-10 (2019)
Abstract Purpose AAZTA (1,4-bis (carboxymethyl)-6-[bis (carboxymethyl)]amino-6-methylperhydro-1,4-diazepine) based chelators were initially developed in the context of magnetic resonance imaging. First radiochemical studies showed the capability of A
Externí odkaz:
https://doaj.org/article/5c3750d7fc0b4121bfa8fc4812a25e44
Autor:
Patricia E. Edem, Jean-Philippe Sinnes, Stefanie Pektor, Nicole Bausbacher, Raffaella Rossin, Abdolreza Yazdani, Matthias Miederer, Andreas Kjær, John F. Valliant, Marc S. Robillard, Frank Rösch, Matthias M. Herth
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-8 (2019)
Abstract Background Pretargeted imaging allows the use of short-lived radionuclides when imaging the accumulation of slow clearing targeting agents such as antibodies. The biotin-(strept)avidin and the bispecific antibody-hapten interactions have bee
Externí odkaz:
https://doaj.org/article/3c3a2b2c7f3b4c0690ccc0893c5a719d
Autor:
Jean-Philippe Sinnes, Johannes Nagel, Bradley P. Waldron, Theodosia Maina, Berthold A. Nock, Ralf K. Bergmann, Martin Ullrich, Jens Pietzsch, Michael Bachmann, Richard P. Baum, Frank Rösch
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract Purpose The widespread use of 68Ga for positron emission tomography (PET) relies on the development of radiopharmaceutical precursors that can be radiolabelled and dispensed in a simple, quick, and convenient manner. The DATA (6-amino-1,4-di
Externí odkaz:
https://doaj.org/article/5b332af26c614df9be3aaf1328b913a8
Autor:
Frank Rösch, Nils Engelbogen, Lukas Greifenstein, Jean-Philippe Sinnes, Ralf Bergmann, Hanane Lahnif, Michael Bachmann
Publikováno v:
ChemMedChem. 15:695-704
The L-lysine urea-L-glutamate (KuE) represents a key motif in recent diagnostic and therapeutic radiopharmaceuticals targeting the prostate specific membrane antigen (PSMA). Using a squaric acid moiety for coupling of KuE with a radioactive label, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f002ea77ca3cc8dd255c57829731d274
https://doi.org/10.1002/cmdc.201900559
https://doi.org/10.1002/cmdc.201900559
Autor:
Jean-Philippe Sinnes, Bauder-Wüst, Ulrike, Schäfer, Martin, Euy Sung Moon, Kopka, Klaus, Rösch, Frank
Additional file 1: Figure 1. Internalization data of the 44Sc complexes of AAZTA5-PSMA-617, AAZTA5 and PSMA-617 in PC3 cells at 37 °C and 4 °C. Figure 2. Internalization data of the 177Lu complexes of AAZTA5-PSMA-617, AAZTA5 and PSMA-617 in PC3 cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e6d6e6540a8f9eb873a539cfb9d2243
Autor:
Lukas, Greifenstein, Nils, Engelbogen, Hanane, Lahnif, Jean-Philippe, Sinnes, Ralf, Bergmann, Michael, Bachmann, Frank, Rösch
Publikováno v:
ChemMedChem. 15(8)
The L-lysine urea-L-glutamate (KuE) represents a key motif in recent diagnostic and therapeutic radiopharmaceuticals targeting the prostate specific membrane antigen (PSMA). Using a squaric acid moiety for coupling of KuE with a radioactive label, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2674e000fb20c992e9d4dc3c21c85b5f
https://pubmed.ncbi.nlm.nih.gov/32057189
https://pubmed.ncbi.nlm.nih.gov/32057189
Autor:
Stefanie Pektor, Matthias Miederer, Andreas Kjaer, Abdolreza Yazdani, Jean-Philippe Sinnes, Nicole Bausbacher, Marc S. Robillard, Patricia E. Edem, Frank Rösch, Raffaella Rossin, John F. Valliant, Matthias M. Herth
Publikováno v:
EJNMMI Research
EJNMMI Research, Vol 9, Iss 1, Pp 1-8 (2019)
Edem, P E, Sinnes, J-P, Pektor, S, Bausbacher, N, Rossin, R, Yazdani, A, Miederer, M, Kjær, A, Valliant, J F, Robillard, M S, Rösch, F & Herth, M M 2019, ' Evaluation of the inverse electron demand Diels-Alder reaction in rats using a scandium-44-labelled tetrazine for pretargeted PET imaging ', EJNMMI Research, vol. 9, no. 1, 49 . https://doi.org/10.1186/s13550-019-0520-y
EJNMMI Research, Vol 9, Iss 1, Pp 1-8 (2019)
Edem, P E, Sinnes, J-P, Pektor, S, Bausbacher, N, Rossin, R, Yazdani, A, Miederer, M, Kjær, A, Valliant, J F, Robillard, M S, Rösch, F & Herth, M M 2019, ' Evaluation of the inverse electron demand Diels-Alder reaction in rats using a scandium-44-labelled tetrazine for pretargeted PET imaging ', EJNMMI Research, vol. 9, no. 1, 49 . https://doi.org/10.1186/s13550-019-0520-y
Background Pretargeted imaging allows the use of short-lived radionuclides when imaging the accumulation of slow clearing targeting agents such as antibodies. The biotin-(strept)avidin and the bispecific antibody-hapten interactions have been applied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f56e0cde4e910f90fa429deaffbb3e60
https://doi.org/10.1186/s13550-019-0520-y
https://doi.org/10.1186/s13550-019-0520-y
Autor:
Berthold A, Nock, Aikaterini, Kaloudi, Johannes, Nagel, Jean-Philippe, Sinnes, Frank, Roesch, Theodosia, Maina
Publikováno v:
Dalton transactions (Cambridge, England : 2003). 46(42)
Molecular imaging of tumors with the PET radionuclide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d38658904ee233804016495892aa624
https://pubmed.ncbi.nlm.nih.gov/28675208
https://pubmed.ncbi.nlm.nih.gov/28675208