Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Jean-Philippe Richard"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Sensory neurons are afferent neurons in sensory systems that convert stimuli and transmit information to the central nervous system as electrical signals. Primary afferent neurons that are affected by non-noxious and noxious stimuli are pres
Externí odkaz:
https://doaj.org/article/55491b657a2941f29bba7cfe73302789
Autor:
Qian Li, Yi Feng, Yingchao Xue, Xiping Zhan, Yi Fu, Gege Gui, Weiqiang Zhou, Jean-Philippe Richard, Arens Taga, Pan Li, Xiaobo Mao, Nicholas J. Maragakis, Mingyao Ying
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-18 (2022)
Abstract Background Spinal cord motor neurons (MNs) from human iPS cells (iPSCs) have wide applications in disease modeling and therapeutic development for amyotrophic lateral sclerosis (ALS) and other MN-associated neurodegenerative diseases. We nee
Externí odkaz:
https://doaj.org/article/70f0c66d888a47efbd6862aa632e9222
Autor:
Bruno Chatenoux, Jean-Philippe Richard, David Small, Claudia Roeoesli, Vladimir Wingate, Charlotte Poussin, Denisa Rodila, Pascal Peduzzi, Charlotte Steinmeier, Christian Ginzler, Achileas Psomas, Michael E. Schaepman, Gregory Giuliani
Publikováno v:
Scientific Data, Vol 8, Iss 1, Pp 1-11 (2021)
Measurement(s) surface reflectance • backscatter Technology Type(s) satellite imaging Sample Characteristic - Location Switzerland Machine-accessible metadata file describing the reported data: https://doi.org/10.6084/m9.figshare.14635485
Externí odkaz:
https://doaj.org/article/4cc41daa55334fdc890863c1c7b3a1e7
Autor:
Umesh Kathad, Aditya Kulkarni, Joseph Ryan McDermott, Jordan Wegner, Peter Carr, Neha Biyani, Rama Modali, Jean-Philippe Richard, Panna Sharma, Kishor Bhatia
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-23 (2021)
Abstract Background Non-targeted cytotoxics with anticancer activity are often developed through preclinical stages using response criteria observed in cell lines and xenografts. A panel of the NCI-60 cell lines is frequently the first line to define
Externí odkaz:
https://doaj.org/article/2b94d396154d4846ad1feef3372616cf
Autor:
Arens Taga, Raha Dastgheyb, Christa Habela, Jessica Joseph, Jean‐Philippe Richard, Sarah K. Gross, Giuseppe Lauria, Gabsang Lee, Norman Haughey, Nicholas J. Maragakis
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 12, Pp 1272-1285 (2019)
Abstract The ability to generate human‐induced pluripotent stem cell (hiPSC)‐derived neural cells displaying region‐specific phenotypes is of particular interest for modeling central nervous system biology in vitro. We describe a unique method
Externí odkaz:
https://doaj.org/article/90f3a373826542afa217b6c5c8f992af
Autor:
Gregory Giuliani, Hugues Cazeaux, Pierre-Yves Burgi, Charlotte Poussin, Jean-Philippe Richard, Bruno Chatenoux
Publikováno v:
Data Science Journal, Vol 20, Iss 1 (2021)
Environmental scientific research is highly becoming data-driven and dependent on high performance computing infrastructures to process ever increasing large volume and diverse data sets. Consequently, there is a growing recognition of the need to sh
Externí odkaz:
https://doaj.org/article/e9e6742a358f4d4ab10b3d5104ab068d
Autor:
Gregory Giuliani, Elvire Egger, Julie Italiano, Charlotte Poussin, Jean-Philippe Richard, Bruno Chatenoux
Publikováno v:
Data, Vol 5, Iss 4, p 100 (2020)
Environmental sustainability is nowadays a major global issue that requires efficient and effective responses from governments. Essential variables (EV) have emerged in different scientific communities as a means to characterize and follow environmen
Externí odkaz:
https://doaj.org/article/7055b63559014176ba84ac671b24c884
Autor:
In Young Choi, HoTae Lim, Kenneth Estrellas, Jyothi Mula, Tatiana V. Cohen, Yuanfan Zhang, Christopher J. Donnelly, Jean-Philippe Richard, Yong Jun Kim, Hyesoo Kim, Yasuhiro Kazuki, Mitsuo Oshimura, Hongmei Lisa Li, Akitsu Hotta, Jeffrey Rothstein, Nicholas Maragakis, Kathryn R. Wagner, Gabsang Lee
Publikováno v:
Cell Reports, Vol 15, Iss 10, Pp 2301-2312 (2016)
Duchenne muscular dystrophy (DMD) remains an intractable genetic disease. Althogh there are several animal models of DMD, there is no human cell model that carries patient-specific DYSTROPHIN mutations. Here, we present a human DMD model using human
Externí odkaz:
https://doaj.org/article/1478ff5e003d4f6bbf35140b1f2ba748
Autor:
Erica Honeck, Roberto Castello, Bruno Chatenoux, Jean-Philippe Richard, Anthony Lehmann, Gregory Giuliani
Publikováno v:
ISPRS International Journal of Geo-Information, Vol 7, Iss 12, p 455 (2018)
Forests represent important habitats for species and provide multiple ecosystem services for human well-being. Preserving forests and other terrestrial ecosystems has become crucial to halt desertification, land degradation, and biodiversity loss wor
Externí odkaz:
https://doaj.org/article/2e31ed85100841969d0b618c61d03757
Autor:
Akshata A. Almad, Arens Taga, Jessica Joseph, Sarah K. Gross, Connor Welsh, Aneesh Patankar, Jean-Philippe Richard, Khalil Rust, Aayush Pokharel, Caroline Plott, Mauricio Lillo, Raha Dastgheyb, Kevin Eggan, Norman Haughey, Jorge E. Contreras, Nicholas J. Maragakis
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 13
Connexin 43 (Cx43) gap junctions and hemichannels mediate astrocyte intercellular communication in the central nervous system under normal conditions and contribute to astrocyte-mediated neurotoxicity in amyotrophic lateral sclerosis (ALS). Here, we