Zobrazeno 1 - 10
of 27 481
pro vyhledávání: '"Jean-Philippe P"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract G protein-coupled receptors naturally oscillate between inactive and active states, often resulting in receptor constitutive activity with important physiological consequences. Among the class C G protein-coupled receptors that typically sen
Externí odkaz:
https://doaj.org/article/9edd1bb4b2fc481a80983bffca4b41c7
Autor:
Chanjuan Xu, Yiwei Zhou, Yuxuan Liu, Li Lin, Peng Liu, Xiaomei Wang, Zhengyuan Xu, Jean-Philippe Pin, Philippe Rondard, Jianfeng Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract G protein-coupled receptors (GPCRs) constitute the largest family of membrane proteins and are important drug targets. The discovery of drugs targeting these receptors and their G protein signaling properties are based on assays mainly perfo
Externí odkaz:
https://doaj.org/article/85a6b4f2dd3241fba99b3d3521990c96
Autor:
Silvia Panarello, Aleix González-Díez, Alice E. Berizzi, Fanny Malhaire, Roser Borràs-Tudurí, Xavier Rovira, Carme Serra, Laurent Prézeau, Jean-Philippe Pin, Cyril Goudet, Amadeu Llebaria, Xavier Gómez-Santacana
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110123- (2024)
Summary: Metabotropic glutamate receptors (mGlu) regulate multiple functions in the nervous systems and are involved in several neurological disorders. However, selectively targeting individual mGlu subtypes with spatiotemporal precision is still an
Externí odkaz:
https://doaj.org/article/b18db773dee3473cb3b7f29e86502ea3
Autor:
Antonio Atalaia, Dagmar Wandrei, Nawel Lalout, Rachel Thompson, Adrian Tassoni, Peter A. C. ’t Hoen, Dimitrios Athanasiou, Suzie-Ann Baker, Paraskevi Sakellariou, Georgios Paliouras, Carla D’Angelo, Rita Horvath, Michelangelo Mancuso, Nadine van der Beek, Cornelia Kornblum, Janbernd Kirschner, Davide Pareyson, Guillaume Bassez, Laura Blacas, Maxime Jacoupy, Catherine Eng, François Lamy, Jean-Philippe Plançon, Jana Haberlova, Esther Brusse, Janneke G. J. Hoeijmakers, Marianne de Visser, Kristl G. Claeys, Carmen Paradas, Antonio Toscano, Vincenzo Silani, Melinda Gyenge, Evy Reviers, Dalil Hamroun, Elisabeth Vroom, Mark D. Wilkinson, Hanns Lochmuller, Teresinha Evangelista
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Background The EURO-NMD Registry collects data from all neuromuscular patients seen at EURO-NMD's expert centres. In-kind contributions from three patient organisations have ensured that the registry is patient-centred, meaningful, and impac
Externí odkaz:
https://doaj.org/article/50645335f24240a3b4537c13391b28b5
Autor:
Marjan Savadkoohi, Marco Pandolfi, Olivier Favez, Jean-Philippe Putaud, Konstantinos Eleftheriadis, Markus Fiebig, Philip K. Hopke, Paolo Laj, Alfred Wiedensohler, Lucas Alados-Arboledas, Susanne Bastian, Benjamin Chazeau, Álvaro Clemente María, Cristina Colombi, Francesca Costabile, David C. Green, Christoph Hueglin, Eleni Liakakou, Krista Luoma, Stefano Listrani, Nikos Mihalopoulos, Nicolas Marchand, Griša Močnik, Jarkko V. Niemi, Jakub Ondráček, Jean-Eudes Petit, Oliver V. Rattigan, Cristina Reche, Hilkka Timonen, Gloria Titos, Anja H. Tremper, Stergios Vratolis, Petr Vodička, Eduardo Yubero Funes, Naděžda Zíková, Roy M. Harrison, Tuukka Petäjä, Andrés Alastuey, Xavier Querol
Publikováno v:
Environment International, Vol 185, Iss , Pp 108553- (2024)
A reliable determination of equivalent black carbon (eBC) mass concentrations derived from filter absorption photometers (FAPs) measurements depends on the appropriate quantification of the mass absorption cross-section (MAC) for converting the absor
Externí odkaz:
https://doaj.org/article/6de57049339a49eb92cfad23f7be9c7b
Autor:
Meritxell Garcia-Marlès, Rosa Lara, Cristina Reche, Noemí Pérez, Aurelio Tobías, Marjan Savadkoohi, David Beddows, Imre Salma, Máté Vörösmarty, Tamás Weidinger, Christoph Hueglin, Nikos Mihalopoulos, Georgios Grivas, Panayiotis Kalkavouras, Jakub Ondráček, Nadĕžda Zíková, Jarkko V. Niemi, Hanna E. Manninen, David C. Green, Anja H. Tremper, Michael Norman, Stergios Vratolis, Konstantinos Eleftheriadis, Francisco J. Gómez-Moreno, Elisabeth Alonso-Blanco, Alfred Wiedensohler, Kay Weinhold, Maik Merkel, Susanne Bastian, Barbara Hoffmann, Hicran Altug, Jean-Eudes Petit, Olivier Favez, Sebastiao Martins Dos Santos, Jean-Philippe Putaud, Adelaide Dinoi, Daniele Contini, Hilkka Timonen, Janne Lampilahti, Tuukka Petäjä, Marco Pandolfi, Philip K. Hopke, Roy M. Harrison, Andrés Alastuey, Xavier Querol
Publikováno v:
Environment International, Vol 185, Iss , Pp 108510- (2024)
Ultrafine particles (UFP, those with diameters ≤ 100 nm), have been reported to potentially penetrate deeply into the respiratory system, translocate through the alveoli, and affect various organs, potentially correlating with increased mortality.
Externí odkaz:
https://doaj.org/article/5b0315b9012b45dfb57fa3d31aec4f92
Autor:
Georgiana Sitoris, Flora Veltri, Malika Ichiche, Pierre Kleynen, Jean-Philippe Praet, Serge Rozenberg, Kris G Poppe
Publikováno v:
European Thyroid Journal, Vol 11, Iss 2, Pp 1-8 (2023)
Objective: Pregnant women with autoimmune (subclinical) hypothyroidism have an increased risk of developing gestational diabetes mellitus (GDM). However, this association remains controversial in euthyroid women with thyroid autoimmunity (TAI). There
Externí odkaz:
https://doaj.org/article/b8e277c0a204441eabc4be6c61b57bd0
Autor:
Jean-Philippe Puyravaud, Samuel A. Cushman, P. Anuradha Reddy, Durairaj Boominathan, Reeta Sharma, Neelakantan Arumugam, Kanagaraj Muthamizh Selvan, Nagarathinam Mohanraj, Sedupathy Arulmozhi, Abdul Rahim, Tamanna Kalam, Rahul De, Swati Udayraj, Andrea Luis, Muneer Ul Islam Najar, Kothandapani Raman, Bawa Mothilal Krishnakumar, Surendra Prakash Goyal, Priya Davidar
Publikováno v:
Conservation, Vol 2, Iss 4, Pp 709-725 (2022)
The Asian elephant is mostly confined to mountainous ranges and therefore risks population fragmentation if hard protected area (PA) boundaries near steep slopes prevent movement. We tested whether elephant gene flow is (i) controlled by slope and (i
Externí odkaz:
https://doaj.org/article/52878a3ba1c94247a25126717b78b9dc
Publikováno v:
Archives of Physiotherapy, Vol 12, Iss 1, Pp 1-4 (2022)
Abstract Background The Cervical Flexion-Rotation Test (CFRT) is widely used in the assessment of upper cervical spine mobility impairments and in the diagnosis of cervicogenic headache (CGH) by physiotherapist. Many studies investigated its differen
Externí odkaz:
https://doaj.org/article/9ad1d654afd94d7e82923fdd2d4f55bb
Autor:
Jean-Philippe Pierron
Publikováno v:
Philosophies, Vol 9, Iss 1, p 5 (2023)
As social and ecological transition and climate change raise issues that go far beyond individual responses, how can these challenges be balanced with ethical and political responses? This article intends to show that the strength of virtue ethics li
Externí odkaz:
https://doaj.org/article/7b227eda30e641f58037fc4f21d500fa