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pro vyhledávání: '"Jean-Philippe Meyer"'
Autor:
Jean-Philippe Meyer
Publikováno v:
In Situ, Vol 17
The two most productive sculptors of the Romanesque period in Alsace, the “Master of Eschau” and “Master of Andlau”, are known for pieces of works that remain of ten religious buildings. The confrontation of this sculptures shows that their a
Externí odkaz:
https://doaj.org/article/4611438375584989af6fd189713b4e0e
Autor:
Jean-Philippe Meyer
Publikováno v:
In Situ, Vol 6
Ribbed vaults appeared in the Romanesque churches of Alsace from about 1140-1150, notably at the abbey church of Murbach and the collegiate church of Lautenbach. This form of vaulting was subsequently found in many small buildings with single naves.
Externí odkaz:
https://doaj.org/article/68a5ab0670cd49108725ecded6bb87b2
Autor:
Johannes Wohlrab, Jean-Philippe Meyer, Yahya Mrestani, Sandy Naumann, Reinhard H.H. Neubert, Andreas Kiesow
Publikováno v:
Journal of Controlled Release. 180:60-70
The penetration behavior into human nails and animal hoof membranes of a novel antifungal agent (EV-086K) for the treatment of onychomycosis was investigated in this study. The new drug provides a high lipophilicity which is adverse for penetration i
Autor:
Lisa Long, Katrine B V Greve, Patrick Roussel, Philipp Knechtle, Jean Philippe Meyer, Federico Brianza, Harald Heider, Melanie Diefenbacher, Christophe Folly, Museer A. Lone, Roger Schneiter, Alexandra Santana Sorensen, Mahmoud A. Ghannoum
Publikováno v:
Antimicrob Agents Chemother.
Human fungal infections represent a therapeutic challenge. Although effective strategies for treatment are available, resistance is spreading, and many therapies have unacceptable side effects. A clear need for novel antifungal targets and molecules
Autor:
Kjell S Sakariassen, Pēteris Alberts, Jean-Philippe Meyer, Alexandra Santana Sorensen, A. Richardson
Publikováno v:
European Journal of Clinical Pharmacology. 69:459-465
This study was performed to determine the oral pharmacokinetics (PK) of EV-077 and its effects on pharmacodynamic (PD) markers. EV-077 blocks prostanoid-induced and isoprostane-induced cellular activation, and is in development for the treatment of v
Autor:
Claudio Mapelli, Ramakrishna Seethala, Songping Han, Ellen Sieber-McMaster, William R. Ewing, Ashish Khanna, Keith L. Constantine, Douglas James Riexinger, Daniel Longhi, John Krupinski, Zhengping Ma, Constance Smith-Monroy, Bastos Margarita M, Dan Shi, Michael S. Bernatowicz, Joseph R. Taylor, Christine Huang, Rajasree Golla, Gordon William Robinson, Jelka Pluscec, Jean M. Whaley, Sesha Natarajan, Jean-Philippe Meyer, Robert H. Stoffel, Li Xin, Ving G. Lee, Barry Koplowitz, Cecilia L Chi, Ildiko Antal-Zimanyi
Publikováno v:
Journal of Medicinal Chemistry. 52:7788-7799
Glucagon-like peptide 1 (GLP-1) is a 30 or 31 amino acid peptide hormone that contributes to the physiological regulation of glucose homeostasis and food intake. Herein, we report the discovery of a novel class of 11 amino acid GLP-1 receptor agonist
Autor:
Jean-Philippe Meyer
Publikováno v:
Revue d’Alsace. :389-417
Créé en 1965, le Service régional de l’Inventaire a réuni depuis cette date, grâce à ses enquêtes sur le terrain, une documentation très considérable sur l’architecture et l’art dans l’ensemble de l’Alsace (Strasbourg et Colmar exc
Publikováno v:
Journal of Medicinal Chemistry. 40:2148-2155
The compound c[Cys5,11]dynorphin A-(1-11)-NH2, 1, is a cyclic dynorphin A analog that shows similar selectivity and potency at the kappa-opioid receptor when compared to the native form of the peptide in central nervous system assays. Previous molecu
Publikováno v:
Tetrahedron Letters. 38:931-934
The solid phase synthesis of cyclic ureas and thioureas is described. The reduction of acylated dipeptides followed by treatment with carbonyldiimidazole or thiocarbonyldiimidazole affords the corresponding cyclic urea or thiourea in good yield and h
Autor:
Pēteris Alberts, Eti Alessandra Femia, Marco Cattaneo, Alexandra Santana Sorensen, Federico Manuel Daray, Wanda Nowak, Jean-Philippe Meyer, Andrea Emilse Errasti, Arnaldo Armesto, Kjell S. Sakariassen, Rodolfo Pedro Rothlin, Mariateresa Pugliano, Cristina Razzari, Gian M. Podda
Publikováno v:
Thrombosis research. 130(5)
INTRODUCTION: This study aimed to characterize the in vitro effect of EV-077, acompound that antagonises the binding of prostanoids and isoprostanes to thethromboxane receptor (TP) and inhibits the thromboxane synthase (TS), on plateletaggregation of