Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Jean-Philippe Deslys"'
Autor:
Héloïse Castiglione, Lucie Madrange, Thomas Lemonnier, Jean-Philippe Deslys, Frank Yates, Pierre-Antoine Vigneron
Publikováno v:
Organoids, Vol 3, Iss 2, Pp 113-125 (2024)
In recent years, 3D cell culture systems have emerged as sophisticated in vitro models, providing valuable insights into human physiology and diseases. The transition from traditional 2D to advanced 3D cultures has introduced novel obstacles, complic
Externí odkaz:
https://doaj.org/article/83bfa4b127b74b6c8acf7e17b8d6b9cb
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
The presence of prion infectivity in the blood of patients affected by variant Creutzfeldt–Jakob disease (v-CJD), the human prion disease linked to the bovine spongiform encephalopathy (BSE), poses the risk of inter-human transmission of this fatal
Externí odkaz:
https://doaj.org/article/45a4276ce905495295d720238b02056f
Autor:
Jean-Yves Douet, Alvina Huor, Hervé Cassard, Séverine Lugan, Naïma Aron, Chloé Mesic, Didier Vilette, Tomás Barrio, Nathalie Streichenberger, Armand Perret-Liaudet, Marie-Bernadette Delisle, Patrice Péran, Jean-Philippe Deslys, Emmanuel Comoy, Jean-Luc Vilotte, Katayoun Goudarzi, Vincent Béringue, Marcelo A. Barria, Diane L. Ritchie, James W. Ironside, Olivier Andréoletti
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-15 (2021)
Abstract Treatment with human pituitary-derived growth hormone (hGH) was responsible for a significant proportion of iatrogenic Creutzfeldt–Jakob disease (iCJD) cases. France and the UK experienced the largest case numbers of hGH-iCJD, with 122 and
Externí odkaz:
https://doaj.org/article/38331de11f744c59b42002fabad71f84
Autor:
Charlotte Gary, Suzanne Lam, Anne-Sophie Hérard, James E. Koch, Fanny Petit, Pauline Gipchtein, Stephen J. Sawiak, Raphaëlle Caillierez, Sabiha Eddarkaoui, Morvane Colin, Fabienne Aujard, Jean-Philippe Deslys, French Neuropathology Network, Emmanuel Brouillet, Luc Buée, Emmanuel E. Comoy, Fabien Pifferi, Jean-Luc Picq, Marc Dhenain
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-21 (2019)
Abstract Alzheimer’s disease is characterized by cognitive alterations, cerebral atrophy and neuropathological lesions including neuronal loss, accumulation of misfolded and aggregated β-amyloid peptides (Aβ) and tau proteins. Iatrogenic inductio
Externí odkaz:
https://doaj.org/article/e39ef7713ddd47a9b3847bf54d779c5c
Autor:
Emmanuel E. Comoy, Jacqueline Mikol, Nina Jaffré, Vincent Lebon, Etienne Levavasseur, Nathalie Streichenberger, Chryslain Sumian, Armand Perret-Liaudet, Marc Eloit, Olivier Andreoletti, Stéphane Haïk, Philippe Hantraye, Jean-Philippe Deslys
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
It is hypothesised that exposure to bovine spongiform encephalopathy through contaminated food could have resulted in a large proportion of latent variant Creutzfeldt-Jakob disease cases in humans. Here the authors demonstrate that inoculation with b
Externí odkaz:
https://doaj.org/article/b0c9168d37d3407aa90721d13daa5b6c
Autor:
Ferid Nassor, Rafika Jarray, Denis S. F. Biard, Auriane Maïza, Dulce Papy-Garcia, Serena Pavoni, Jean-Philippe Deslys, Frank Yates
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Human brain organoids (mini-brains) consist of self-organized three-dimensional (3D) neural tissue which can be derived from reprogrammed adult cells and maintained for months in culture. These 3D structures manifest substantial potential for the mod
Externí odkaz:
https://doaj.org/article/f8eef2923c7546f481175a47f14cc304
Autor:
Serena Pavoni, Rafika Jarray, Ferid Nassor, Anne-Cécile Guyot, Steve Cottin, Jessica Rontard, Jacqueline Mikol, Aloïse Mabondzo, Jean-Philippe Deslys, Frank Yates
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209150 (2018)
Human mini-brains (MB) are cerebral organoids that recapitulate in part the complexity of the human brain in a unique three-dimensional in vitro model, yielding discrete brain regions reminiscent of the cerebral cortex. Specific proteins linked to ne
Externí odkaz:
https://doaj.org/article/42b286926f5245ecbb4e3f4752714fc2
Autor:
Silvia Vanni, Marco Zattoni, Fabio Moda, Giorgio Giaccone, Fabrizio Tagliavini, Stéphane Haïk, Jean-Philippe Deslys, Gianluigi Zanusso, James W. Ironside, Margarita Carmona, Isidre Ferrer, Gabor G. Kovacs, Giuseppe Legname
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Background: Hemoglobin is the major protein found in erythrocytes, where it acts as an oxygen carrier molecule. In recent years, its expression has been reported also in neurons and glial cells, although its role in brain tissue remains still unknown
Externí odkaz:
https://doaj.org/article/34f9182ba17343cebfe219d643d7ffc9
Autor:
Paul Brown, Juan Maria Torres, Juergen A. Richt, Justin J. Greenlee, Cristina Casalone, Evelyne Correia, Capucine Dehen, Sophie Luccantoni-Freire, Valérie Durand, Marie-Madeleine Ruchoux, Jacqueline Mikol, Emmanuel E. Comoy, Jean-Philippe Deslys
Publikováno v:
Pathogens, Vol 2, Iss 3, Pp 520-532 (2013)
Successful transmission of Transmissible Mink Encephalopathy (TME) to cattle supports the bovine hypothesis for the still controversial origin of TME outbreaks. Human and primate susceptibility to classical Bovine Spongiform Encephalopathy (c-BSE) an
Externí odkaz:
https://doaj.org/article/47cd2175779f42a581a05b230271bf8d
Autor:
Emmanuel E Comoy, Cristina Casalone, Nathalie Lescoutra-Etchegaray, Gianluigi Zanusso, Sophie Freire, Dominique Marcé, Frédéric Auvré, Marie-Magdeleine Ruchoux, Sergio Ferrari, Salvatore Monaco, Nicole Salès, Maria Caramelli, Philippe Leboulch, Paul Brown, Corinne I Lasmézas, Jean-Philippe Deslys
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e3017 (2008)
BACKGROUND: Human variant Creutzfeldt-Jakob Disease (vCJD) results from foodborne transmission of prions from slaughtered cattle with classical Bovine Spongiform Encephalopathy (cBSE). Atypical forms of BSE, which remain mostly asymptomatic in aging
Externí odkaz:
https://doaj.org/article/cde7cdfc27f54204bb60506cf5f46bc5