Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jean-Philippe Cosse"'
Autor:
Roland Hubaux, Fabian Vandermeers, Jean-Philippe Cosse, Cecilia Crisanti, Veena Kapoor, Steven M. Albelda, Céline Mascaux, Philippe Delvenne, Pascale Hubert, Luc Willems
Publikováno v:
ERJ Open Research, Vol 1, Iss 2 (2015)
With 5-year survival rates below 5%, small cell lung carcinoma (SCLC) has very poor prognosis and requires improved therapies. Despite an excellent overall response to first-line therapy, relapses are frequent and further treatments are disappointing
Externí odkaz:
https://doaj.org/article/5be665524cca4f6d88c2b0a35367a064
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 10, Pp 976-986 (2009)
Tumor hypoxia is one of the features of tumor microenvironment that contributes to chemoresistance in particular by cellular adaptations that modulate the apoptotic process. However, the mechanisms involved in this resistance still need deeper unders
Externí odkaz:
https://doaj.org/article/d45d1c62c6d24bb092acfa4728897d98
Autor:
Philippe Delvenne, Veena Kapoor, C. Mascaux, Steven M. Albelda, Luc Willems, Fabian Vandermeers, Cecilia Crisanti, Roland Hubaux, Jean-Philippe Cosse, Pascale Hubert
Publikováno v:
ERJ Open Research
ERJ Open Research, Vol 1, Iss 2 (2015)
ERJ Open Research, Vol 1, Iss 2 (2015)
With 5-year survival rates below 5%, small cell lung carcinoma (SCLC) has very poor prognosis and requires improved therapies. Despite an excellent overall response to first-line therapy, relapses are frequent and further treatments are disappointing
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 10, Pp 976-986 (2009)
Tumor hypoxia is one of the features of tumor microenvironment that contributes to chemoresistance in particular by cellular adaptations that modulate the apoptotic process. However, the mechanisms involved in this resistance still need deeper unders
Autor:
Jean-Philippe Cosse, Carine Michiels
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 8:790-797
A solid tumour forms an organ-like structure that is comprised of cancer cells as well as stroma cells (fibroblasts, inflammatory cells) that are embedded in an extracellular matrix and are nourished by vascular network. However, tumoral microenviron
Autor:
Amel Bouzar, Nicolas Gillet, Luc Willems, Michal Reichert, Jean-Rock Jacques, Alix de Brogniez, Jean-Philippe Cosse, Isabelle Callebaut
Publikováno v:
Journal of Virology
Journal of Virology, American Society for Microbiology, 2015, 89 (17), pp.1. ⟨10.1128/JVI.00261-15⟩
Journal of Virology, 2015, 89 (17), pp.1. ⟨10.1128/JVI.00261-15⟩
Journal of Virology, American Society for Microbiology, 2015, 89 (17), pp.1. ⟨10.1128/JVI.00261-15⟩
Journal of Virology, 2015, 89 (17), pp.1. ⟨10.1128/JVI.00261-15⟩
Viruses have coevolved with their host to ensure efficient replication and transmission without inducing excessive pathogenicity that would indirectly impair their persistence. This is exemplified by the bovine leukemia virus (BLV) system in which ly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a762aee19fe3d27f6817abaffd3878c2
https://hal.archives-ouvertes.fr/hal-01195779
https://hal.archives-ouvertes.fr/hal-01195779
Publikováno v:
Experimental Cell Research. 312(15):2908-2920
Tumor hypoxia has been described to increase the resistance of cancer cells to radiation therapy and chemotherapy. It also supports the invasiveness and metastatic potential of the tumor. However, few data are available on the transduction pathway se
Autor:
Jean-Pascal Piret, Martine Raes, Christophe Debacq, Carine Michiels, Emmanuel Minet, Noelle Ninane, Jean-Philippe Cosse
Publikováno v:
Journal of Biological Chemistry. 280:9336-9344
Increased levels of Mcl-1 (myeloid cell factor-1) have been reported in several cancers, suggesting an important role played by Mcl-1 in cancer cell survival. Mcl-1 is an anti-apoptotic protein shown to delay or block apoptosis. In this work, using s
Autor:
Luc Willems, Fabian Vandermeers, Roland Hubaux, Jean-Philippe Cosse, Sathya Neelature Sriramareddy, Chrisostome Costa
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 81(3)
Malignant pleural mesothelioma (MPM) is an almost invariably fatal cancer of the pleura due to asbestos exposure. Increasing evidence indicates that unresponsiveness to chemotherapy is due to epigenetic errors leading to inadequate gene expression in
Publikováno v:
Biochemical Pharmacology
Biochemical Pharmacology, Elsevier, 2010, 80 (8), pp.1160. ⟨10.1016/j.bcp.2010.07.009⟩
Biochemical Pharmacology, Elsevier, 2010, 80 (8), pp.1160. ⟨10.1016/j.bcp.2010.07.009⟩
Tumor hypoxia is a common characteristic of most solid tumors and is correlated with poor prognosis for patients partly because hypoxia promotes resistance to cancer therapy. Hypoxia selects cancer cells that are resistant to apoptosis and allows the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ef6036ce906f23ac8b4c444d6bf101
https://hal.archives-ouvertes.fr/hal-00618178/file/PEER_stage2_10.1016%2Fj.bcp.2010.07.009.pdf
https://hal.archives-ouvertes.fr/hal-00618178/file/PEER_stage2_10.1016%2Fj.bcp.2010.07.009.pdf