Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jean-Philippe Blanck"'
Autor:
Valentina Ceglia, Erin J. Kelley, Annalee S. Boyle, Sandra Zurawski, Heather L. Mead, Caroline E. Harms, Jean-Philippe Blanck, Anne-Laure Flamar, Jung Hwa Kirschman, Paul Ogongo, Joel D. Ernst, Yves Levy, Gerard Zurawski, John A. Altin
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Common approaches for monitoring T cell responses are limited in their multiplexity and sensitivity. In contrast, deep sequencing of the T Cell Receptor (TCR) repertoire provides a global view that is limited only in terms of theoretical sensitivity
Externí odkaz:
https://doaj.org/article/f93445a02b2b471c835e0f59d1527059
Autor:
Paul Ogongo, Anne-Laure Flamar, Jung Hwa Kirschman, Heather L. Mead, Jean-Philippe Blanck, Joel D. Ernst, Sandra Zurawski, Caroline E. Harms, Annalee S. Boyle, Erin Kelley, John A. Altin, Gerard Zurawski, Yves Levy, Valentina Ceglia
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Common approaches for monitoring T cell responses are limited in their multiplexity and sensitivity. In contrast, deep sequencing of the T Cell Receptor (TCR) repertoire provides a global view that is limited only in terms of theoretical sensitivity
Autor:
Simone Caielli, Jean-Philippe Blanck, Raphaela Goldbach-Mansky, Julie Fuller, Virginia Pascual, Tracey Wright, Jacques Banchereau, Jeanine Baisch, Katie Stewart, Seunghee Hong, Lorien Nassi, Preetha Balasubramanian, Lynnette Walters, Jinghua Gu, Marina Ohouo, Jacob Cardenas, Cristy Stagnar, Adriana Almeida de Jesus
Publikováno v:
Cell
Nat Immunol
Nat Immunol
Emerging evidence supports that mitochondrial dysfunction contributes to Systemic Lupus Erythematosus (SLE) pathogenesis. Here we show that programmed mitochondrial removal, a hallmark of mammalian erythropoiesis, is defective in SLE. Specifically, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79f21a807a857a1761a57a68c92ebfdf
https://europepmc.org/articles/PMC8380737/
https://europepmc.org/articles/PMC8380737/
Autor:
Yoichiro Ohne, Jonathan S Silver, LuAnn Thompson-Snipes, Magalie A Collet, Jean Philippe Blanck, Brandi L Cantarel, Alan M Copenhaver, Alison A Humbles, Yong-Jun Liu
Publikováno v:
Nature immunology. 17(8)
Autor:
Jean-Philippe Blanck, Sandra Clayton, Yanying Cao, LuAnn Thompson-Snipes, Jacques Banchereau, Eynav Klechevsky, Jean-Pierre Gorvel, Gerard Zurawski, Sandra Zurawski
Publikováno v:
Blood. 119:5742-5749
We recently reported that human epidermal Langerhans cells (LCs) are more efficient than dermal CD14+ DCs at priming naive CD8+ T cells into potent CTLs. We hypothesized that distinctive dendritic cell (DC) cytokine expression profiles (ie, IL-15 pro
Autor:
Peter Klucar, Yoram Reiter, A. Karolina Palucka, Olivier Agouna-Deciat, Amy O'Bar, Sandra Zurawski, Jacques Banchereau, LuAnn Thompson-Snipes, Eynav Klechevsky, Gerard Zurawski, Anne-Laure Flamar, Maochang Liu, Jean-Philippe Blanck, Yanying Cao
Publikováno v:
Blood. 116:1685-1697
We evaluated human CD8+ T-cell responses generated by targeting antigens to dendritic cells (DCs) through various lectin receptors. We found the immunoreceptor tyrosine-based inhibitory motif-containing DC immunoreceptor (DCIR) to mediate potent cros
Autor:
Yoichiro Ohne, Magalie A. Collet, Brandi L. Cantarel, Jean-Philippe Blanck, Alan M. Copenhaver, Lu Ann Thompson-Snipes, Jonathan S. Silver, Alison A. Humbles, Yong-Jun Liu
Publikováno v:
Nature immunology. 17(6)
Group 2 innate lymphoid cells (ILC2 cells) are important for type 2 immune responses and are activated by the epithelial cytokines interleukin 33 (IL-33), IL-25 and thymic stromal lymphopoietin (TSLP). Here we demonstrated that IL-1β was a critical
Autor:
Joseph W. Fay, Hideki Ueno, Jacques Banchereau, Dennis A. Johnston, John E. Connolly, Fabienne Kerneis-Norvell, Jean-Philippe Blanck, Anna Karolina Palucka
Publikováno v:
Journal of Immunotherapy. 29:545-557
Dendritic cells (DCs) loaded with killed allogeneic tumors can cross-prime tumor-specific naive CD8 T cells in vitro, thereby providing an option to overcome human leukocyte antigen restriction inherent to loading DC vaccines with peptides. We have v
Autor:
Dorothée Duluc, Sangkon Oh, Nicole Baldwin, Muriel Boreham, Jean-Philippe Blanck, Seunghee Hong, Jose Rossello-Urgell, Romain Banchereau, LuAnn Thompson-Snipes, Jack Stecher, Michael Carley, Sandra Zurawski, Virginia Pascual, Gerard Zurawski, Julien Gannevat
Publikováno v:
Genome Medicine
Background Dendritic cells localize throughout the body, where they can sense and capture invading pathogens to induce protective immunity. Hence, harnessing the biology of tissue-resident dendritic cells is fundamental for the rational design of vac
Autor:
Jacques Banchereau, Jean Philippe Blanck, Virginia Pascual, Lynda B. Bennett, A. Karolina Palucka
Publikováno v:
Proceedings of the National Academy of Sciences. 102:3372-3377
Cytokines, most particularly TNF and type I IFN (IFN-αβ), have been long considered essential elements in the development of autoimmunity. Identification of TNF in the pathogenesis of rheumatoid arthritis and TNF antagonist therapy represent succes