Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jean-Philippe Meyer"'
Autor:
Johannes Wohlrab, Jean-Philippe Meyer, Yahya Mrestani, Sandy Naumann, Reinhard H.H. Neubert, Andreas Kiesow
Publikováno v:
Journal of Controlled Release. 180:60-70
The penetration behavior into human nails and animal hoof membranes of a novel antifungal agent (EV-086K) for the treatment of onychomycosis was investigated in this study. The new drug provides a high lipophilicity which is adverse for penetration i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c09757dce5749a25b84acd1bfaa6a10a
https://doi.org/10.1016/j.jconrel.2014.02.013
https://doi.org/10.1016/j.jconrel.2014.02.013
Autor:
Lisa Long, Katrine B V Greve, Patrick Roussel, Philipp Knechtle, Jean Philippe Meyer, Federico Brianza, Harald Heider, Melanie Diefenbacher, Christophe Folly, Museer A. Lone, Roger Schneiter, Alexandra Santana Sorensen, Mahmoud A. Ghannoum
Publikováno v:
Antimicrob Agents Chemother.
Human fungal infections represent a therapeutic challenge. Although effective strategies for treatment are available, resistance is spreading, and many therapies have unacceptable side effects. A clear need for novel antifungal targets and molecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb465b443198ccc5f3666eea08ecd077
http://aac.asm.org/content/58/1/455.full
http://aac.asm.org/content/58/1/455.full
Autor:
Kjell S Sakariassen, Pēteris Alberts, Jean-Philippe Meyer, Alexandra Santana Sorensen, A. Richardson
Publikováno v:
European Journal of Clinical Pharmacology. 69:459-465
This study was performed to determine the oral pharmacokinetics (PK) of EV-077 and its effects on pharmacodynamic (PD) markers. EV-077 blocks prostanoid-induced and isoprostane-induced cellular activation, and is in development for the treatment of v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a0599e2934f9c7cac16fc2ee89b4a4
https://doi.org/10.1007/s00228-012-1348-9
https://doi.org/10.1007/s00228-012-1348-9
Autor:
Claudio Mapelli, Ramakrishna Seethala, Songping Han, Ellen Sieber-McMaster, William R. Ewing, Ashish Khanna, Keith L. Constantine, Douglas James Riexinger, Daniel Longhi, John Krupinski, Zhengping Ma, Constance Smith-Monroy, Bastos Margarita M, Dan Shi, Michael S. Bernatowicz, Joseph R. Taylor, Christine Huang, Rajasree Golla, Gordon William Robinson, Jelka Pluscec, Jean M. Whaley, Sesha Natarajan, Jean-Philippe Meyer, Robert H. Stoffel, Li Xin, Ving G. Lee, Barry Koplowitz, Cecilia L Chi, Ildiko Antal-Zimanyi
Publikováno v:
Journal of Medicinal Chemistry. 52:7788-7799
Glucagon-like peptide 1 (GLP-1) is a 30 or 31 amino acid peptide hormone that contributes to the physiological regulation of glucose homeostasis and food intake. Herein, we report the discovery of a novel class of 11 amino acid GLP-1 receptor agonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f59d43fbd51aab4facd89ceaa788aab6
https://doi.org/10.1021/jm900752a
https://doi.org/10.1021/jm900752a
Autor:
Jean-Philippe Meyer
Publikováno v:
Revue d’Alsace. :389-417
Créé en 1965, le Service régional de l’Inventaire a réuni depuis cette date, grâce à ses enquêtes sur le terrain, une documentation très considérable sur l’architecture et l’art dans l’ensemble de l’Alsace (Strasbourg et Colmar exc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c610517653f439fdfba6a6c9a1d423d1
https://doi.org/10.4000/alsace.1430
https://doi.org/10.4000/alsace.1430
Publikováno v:
Journal of Medicinal Chemistry. 40:2148-2155
The compound c[Cys5,11]dynorphin A-(1-11)-NH2, 1, is a cyclic dynorphin A analog that shows similar selectivity and potency at the kappa-opioid receptor when compared to the native form of the peptide in central nervous system assays. Previous molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc429ec6579df29d8c6651b125c794ee
https://doi.org/10.1021/jm960562m
https://doi.org/10.1021/jm960562m
Publikováno v:
Tetrahedron Letters. 38:931-934
The solid phase synthesis of cyclic ureas and thioureas is described. The reduction of acylated dipeptides followed by treatment with carbonyldiimidazole or thiocarbonyldiimidazole affords the corresponding cyclic urea or thiourea in good yield and h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dd7cc5faca63aa593204f799b61daf8
https://doi.org/10.1016/s0040-4039(96)02516-6
https://doi.org/10.1016/s0040-4039(96)02516-6
Autor:
Pēteris Alberts, Eti Alessandra Femia, Marco Cattaneo, Alexandra Santana Sorensen, Federico Manuel Daray, Wanda Nowak, Jean-Philippe Meyer, Andrea Emilse Errasti, Arnaldo Armesto, Kjell S. Sakariassen, Rodolfo Pedro Rothlin, Mariateresa Pugliano, Cristina Razzari, Gian M. Podda
Publikováno v:
Thrombosis research. 130(5)
INTRODUCTION: This study aimed to characterize the in vitro effect of EV-077, acompound that antagonises the binding of prostanoids and isoprostanes to thethromboxane receptor (TP) and inhibits the thromboxane synthase (TS), on plateletaggregation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::600421aa5dd9ea73c48cdf1bb808800b
https://pubmed.ncbi.nlm.nih.gov/22959706
https://pubmed.ncbi.nlm.nih.gov/22959706
Autor:
Jean-Philippe Meyer
Publikováno v:
In Situ : Revue de Patrimoines, Vol 17 (2012)
Les deux sculpteurs romans les plus productifs en Alsace, le Maître d’Eschau et le Maître d’Andlau, sont connus par des œuvres réalisées pour une dizaine d’édifices religieux. La confrontation entre elles montre que leurs auteurs travaill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c04208d0d3008ff536b332da35e3b97c
http://journals.openedition.org/insitu/7601
http://journals.openedition.org/insitu/7601
Autor:
Jean-Jacques Laplante, Jean-Philippe Meyer, Paul Rohmer, Philippe Mercet, Jean-Philippe Miguet, Patrick Jacquier, Bruno Gottstein, Solange Bresson-Hadni, D. Lenys, Dominique-Angèle Vuitton
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 51:837-846
In a serologic survey for Echinococcus multilocularis infection, we screened sera from 7,884 subjects from the Doubs Departement in France, an area endemic for alveolar echinococcosis (AE) of the liver. An enzyme-linked immunosorbent assay (ELISA) wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::932f0e1f1973770eb0c01745d91c39e5
https://doi.org/10.4269/ajtmh.1994.51.837
https://doi.org/10.4269/ajtmh.1994.51.837