Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Jean-Paul Vernot"'
Autor:
Natalia Ospina-Muñoz, Jean-Paul Vernot
Publikováno v:
Tumor Biology, Vol 42 (2020)
The interleukin-8 is an important regulator of the tumor microenvironment, promoting the epithelial–mesenchymal transition and the acquisition of stem-like cell properties in cancer cells. The tumorsphere-formation assay has been used for the ident
Externí odkaz:
https://doaj.org/article/2d818905c58e48638a5704fa5edd8a97
Autor:
Paola Fernanda Ruiz-Aparicio, Gloria Inés Uribe, Adriana Linares-Ballesteros, Jean-Paul Vernot
Publikováno v:
Molecules, Vol 26, Iss 17, p 5366 (2021)
Cell adhesion to stromal support and the associated intracellular signaling are central to drug resistance, therefore blocking both has been effective in increasing drug sensitization in leukemia. The stromal Ser/Thr protein kinase C (PKC) has been f
Externí odkaz:
https://doaj.org/article/fc275a95a4024d3487da7d4aef7c120f
Publikováno v:
Cell Communication and Signaling, Vol 15, Iss 1, Pp 1-18 (2017)
Abstract Background There is compelling evidence associating senescent cells with the malignant progression of tumours. Of all senescence-related mechanisms, the so-called senescence-associated secretory phenotype (SASP) has attracted much attention.
Externí odkaz:
https://doaj.org/article/4ef6142a8dee4909a4a5b023119d0f75
Autor:
Víctor Alfonso Solarte, Paulette Conget, Jean-Paul Vernot, Jaiver Eduardo Rosas, Zuly Jenny Rivera, Javier Eduardo García, Martha Ligia Arango-Rodríguez
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174707 (2017)
Oral squamous cell carcinoma is the fifth most common epithelial cancer in the world, and its current clinical treatment has both low efficiency and poor selectivity. Cationic amphipathic peptides have been proposed as new drugs for the treatment of
Externí odkaz:
https://doaj.org/article/8abd16810f314624bb58c1748a6cd862
Autor:
Jean-Paul Vernot, Ana María Perdomo-Arciniegas, Luis Alberto Pérez-Quintero, Diego Fernando Martínez
Publikováno v:
Journal of Immunology Research, Vol 2015 (2015)
The Lck interacting protein Tip of Herpesvirus saimiri is responsible for T-cell transformation both in vitro and in vivo. Here we designed the chimeric peptide hTip-CSKH, comprising the Lck specific interacting motif CSKH of Tip and its hydrophobic
Externí odkaz:
https://doaj.org/article/937abf0fa86b4b07b216fe26f0432796
Autor:
Jean Paul Vernot
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
The well-recognized cell phenotypic heterogeneity in tumors is a great challenge for cancer treatment. Dynamic interconversion and movement within a spectrum of different cell phenotypes (cellular plasticity) with the acquisition of specific cell fun
Externí odkaz:
https://doaj.org/article/951aa024f7cf4f918ccfa2f696f9fc72
Publikováno v:
International journal of molecular sciences. 23(13)
Cellular senescence is recognized as a dynamic process in which cells evolve and adapt in a context dependent manner; consequently, senescent cells can exert both beneficial and deleterious effects on their surroundings. Specifically, senescent mesen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f456f1a182768b8096bdb3b5b1372b2f
https://pubmed.ncbi.nlm.nih.gov/35806354
https://pubmed.ncbi.nlm.nih.gov/35806354
Autor:
Jean-Paul Vernot, Natalia-Del Pilar Vanegas, Paola Fernanda Ruiz-Aparicio, Gloria Inés Uribe, Adriana Linares-Ballesteros
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 8166, p 8166 (2021)
Volume 22
Issue 15
International Journal of Molecular Sciences, Vol 22, Iss 8166, p 8166 (2021)
Leukemic cell growth in the bone marrow (BM) induces a very stressful condition. Mesenchymal stem cells (MSC), a key component of this BM niche, are affected in several ways with unfavorable consequences on hematopoietic stem cells favoring leukemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e7588e3fa357328b77dd3f69d699e31
Autor:
Jean-Paul Vernot, Jessica Flechas-Afanador, Camila Cadavid-Cortés, Natalia-Del Pilar Vanegas, Gloria Inés Uribe, Jimmy Lagos, Paola Ortiz-Montero, Adriana Linares-Ballesteros, Paola Fernanda Ruiz-Aparicio
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 3705, p 3705 (2020)
Volume 21
Issue 10
International Journal of Molecular Sciences, Vol 21, Iss 3705, p 3705 (2020)
Volume 21
Issue 10
Mesenchymal stem cells (MSC) favour a scenario where leukemic cells survive. The protein kinase C (PKC) is essential to confer MSC support to leukemic cells and may be responsible for the intrinsic leukemic cell growth. Here we have evaluated the cap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c545ada633d83e90a827fa457b6a9dd
http://europepmc.org/articles/PMC7279155
http://europepmc.org/articles/PMC7279155
Autor:
Ricardo Fierro-Medina, Andrea Barragán-Cárdenas, Victor Alfonso Niño‐Ramírez, Maribel Urrea-Pelayo, Jean Paul Vernot, Claudia M. Parra-Giraldo, Javier Eduardo García-Castañeda, Adriana Umaña-Pérez, Zuly Jenny Rivera-Monroy
Publikováno v:
RSC advances. 10(30)
The cytotoxic effect against the breast cancer cell line MDA-MB-468 of the palindromic peptide LfcinB (21–25)Pal: 1RWQWRWQWR9 and its analogous peptides, obtained via alanine scanning, was evaluated. The results indicate that the palindromic peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c1cf0f10007f6e649af7420c50cee62
https://pubmed.ncbi.nlm.nih.gov/35515633
https://pubmed.ncbi.nlm.nih.gov/35515633