Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Jean-Paul Vernot"'
Autor:
Natalia Ospina-Muñoz, Jean-Paul Vernot
Publikováno v:
Tumor Biology, Vol 42 (2020)
The interleukin-8 is an important regulator of the tumor microenvironment, promoting the epithelial–mesenchymal transition and the acquisition of stem-like cell properties in cancer cells. The tumorsphere-formation assay has been used for the ident
Externí odkaz:
https://doaj.org/article/2d818905c58e48638a5704fa5edd8a97
Autor:
Jean Paul Vernot
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
The well-recognized cell phenotypic heterogeneity in tumors is a great challenge for cancer treatment. Dynamic interconversion and movement within a spectrum of different cell phenotypes (cellular plasticity) with the acquisition of specific cell fun
Externí odkaz:
https://doaj.org/article/951aa024f7cf4f918ccfa2f696f9fc72
Autor:
Paola Fernanda Ruiz-Aparicio, Gloria Inés Uribe, Adriana Linares-Ballesteros, Jean-Paul Vernot
Publikováno v:
Molecules, Vol 26, Iss 17, p 5366 (2021)
Cell adhesion to stromal support and the associated intracellular signaling are central to drug resistance, therefore blocking both has been effective in increasing drug sensitization in leukemia. The stromal Ser/Thr protein kinase C (PKC) has been f
Externí odkaz:
https://doaj.org/article/fc275a95a4024d3487da7d4aef7c120f
Publikováno v:
Cell Communication and Signaling, Vol 15, Iss 1, Pp 1-18 (2017)
Abstract Background There is compelling evidence associating senescent cells with the malignant progression of tumours. Of all senescence-related mechanisms, the so-called senescence-associated secretory phenotype (SASP) has attracted much attention.
Externí odkaz:
https://doaj.org/article/4ef6142a8dee4909a4a5b023119d0f75
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Mesenchymal stem cells (MSC) constitute an important cell population of the bone marrow hematopoietic niche that supports normally hematopoietic stem cells (HSC) but eventually also leukemic cells. The alterations that occur in the MSC under leukemic
Externí odkaz:
https://doaj.org/article/b91d961abdef4c2aa6ff71bd7b1f2e6b
Autor:
Víctor Alfonso Solarte, Paulette Conget, Jean-Paul Vernot, Jaiver Eduardo Rosas, Zuly Jenny Rivera, Javier Eduardo García, Martha Ligia Arango-Rodríguez
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174707 (2017)
Oral squamous cell carcinoma is the fifth most common epithelial cancer in the world, and its current clinical treatment has both low efficiency and poor selectivity. Cationic amphipathic peptides have been proposed as new drugs for the treatment of
Externí odkaz:
https://doaj.org/article/8abd16810f314624bb58c1748a6cd862
Publikováno v:
International journal of molecular sciences. 23(13)
Cellular senescence is recognized as a dynamic process in which cells evolve and adapt in a context dependent manner; consequently, senescent cells can exert both beneficial and deleterious effects on their surroundings. Specifically, senescent mesen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f456f1a182768b8096bdb3b5b1372b2f
https://pubmed.ncbi.nlm.nih.gov/35806354
https://pubmed.ncbi.nlm.nih.gov/35806354
Publikováno v:
Caldasia, Vol 30, Iss 2, Pp 325-336 (2008)
La cadena z es una proteína transmembranal que se encuentra en los linfocitos T, uno de los tipos de células más importantes en el sistema inmune adaptativo, haciendo parte de un complejo multimérico que se ubica en la superficie de la célula y
Externí odkaz:
https://doaj.org/article/e0396ee1265f4634925a25eb0c83a4d6
Publikováno v:
Biomédica: revista del Instituto Nacional de Salud, Vol 28, Iss 2, Pp 262-270 (2008)
Introducción. El complejo asociado al receptor de las células T está constituido por las moléculas CD3 (δ, γ, ε) y las cadenas ζ, todas proteínas transmembrana esenciales para la transducción de señales durante la activación del linfocito
Externí odkaz:
https://doaj.org/article/ed4b1ff5a8474f0c86d6e23130357ecd
Autor:
Jean-Paul Vernot, Ana María Perdomo-Arciniegas, Luis Alberto Pérez-Quintero, Diego Fernando Martínez
Publikováno v:
Journal of Immunology Research, Vol 2015 (2015)
The Lck interacting protein Tip of Herpesvirus saimiri is responsible for T-cell transformation both in vitro and in vivo. Here we designed the chimeric peptide hTip-CSKH, comprising the Lck specific interacting motif CSKH of Tip and its hydrophobic
Externí odkaz:
https://doaj.org/article/937abf0fa86b4b07b216fe26f0432796