Breast Carcinoma, Intratumour Heterogeneity and Histological Grading, Using Geostatistics

Autor: Vénus Sharifi‐Salamatian, Anne de Roquancourt, Jean Paul Rigaut

Publikováno v: Analytical Cellular Pathology, Vol 20, Iss 2-3, Pp 83-91 (2000)

Tumour progression is currently believed to result from genetic instability. Chromosomal patterns specific of a type of cancer are frequent even though phenotypic spatial heterogeneity is omnipresent. The latter is the usual cause of histological gra

Externí odkaz: https://doaj.org/article/e8e4043d10a84e8786d215e477f68498

Quantitative analysis of cytokeratin network topology in the MCF7 cell line

Autor: Jany Vassy, Stéphanie Portet, Abdelhamid Hebbache, G. Millot, Michael Beil, Jean Paul Rigaut, D. Schoevaert

Publikováno v: Cytometry. 35:203-213

Background: In the MCF7 human breast cancer cell line, several patterns of cytokeratin networks are observed, depending on the intracellular localization. Our hypothesis is that architectural variations of cytokeratin networks depend on local tension

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b7e30f14d8cc845e962a53453faf0c7e
https://doi.org/10.1002/(sici)1097-0320(19990301)35:3<203::aid-cyto3>3.0.co

Strong decrease in biotin content may correlate with metabolic alterations in colorectal adenocarcinoma

Autor: Laure Sabatier, Corinne L. Cherbonnel-Lasserre, Bernard Dutrillaux, Gustavo Linares-Cruz, Jean-Paul Rigaut

Publikováno v: International Journal of Cancer. 72:768-775

Short-chain fatty acids are an important source of energy for colonocytes. One of these is propionate, which is metabolized through carboxylation by propionyl-CoA carboxylase (PCC), an enzyme encoded by 2 genes, PCCA and PCCB. The co-factor of this r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae0e813d5e4ef6bffbbcfad82e85877
https://doi.org/10.1002/(sici)1097-0215(19970904)72:5<768::aid-ijc11>3.0.co

Dynamic Changes in Quantitative Features of Human Gastric Lesions

Autor: Jean Paul Rigaut, Ventzeslav Enchev

Publikováno v: Analytical Cellular Pathology, Vol 13, Iss 1, Pp 9-16 (1997)
Analytical Cellular Pathology : the Journal of the European Society for Analytical Cellular Pathology

Quantitative DNA, morphometric cellular and nuclear variables were evaluated in surgical biopsies from patients with various gastric lesions: chronic gastritis, chronic ulcers, adenomatous polyps (gastric adenomas), primary carcinomas and their corre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033c80d4d572e9914e29d0b4dad1420c
https://doaj.org/article/c4462f2b5dd44cea8efcd426769ed6d2

Computer simulation modelling and visualization of 3D architecture of biological tissues

Autor: Jean Paul Rigaut, Carole J. Clem

Publikováno v: Acta Biotheoretica. 43:425-442

Recent technical improvements, such as 3D microscopy imaging, have shown the necessity of studying 3D biological tissue architecture during carcinogenesis. In the present paper a computer simulation model is developed allowing the visualization of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4daa9050091bf3d372c1b022f8afc68
https://doi.org/10.1007/bf00713563