Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Jean-Paul Païs De Barros"'
Autor:
Aleksandra Georgievski, Pierre-Simon Bellaye, Benjamin Tournier, Hélène Choubley, Jean-Paul Pais de Barros, Michaële Herbst, Arnaud Béduneau, Patrick Callier, Bertrand Collin, Frédérique Végran, Paola Ballerini, Carmen Garrido, Ronan Quéré
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-17 (2024)
Abstract We created valrubicin-loaded immunoliposomes (Val-ILs) using the antitumor prodrug valrubicin, a hydrophobic analog of daunorubicin. Being lipophilic, valrubicin readily incorporated Val-lLs that were loaded with specific antibodies. Val-ILs
Externí odkaz:
https://doaj.org/article/37e10694d8ae4fb1b128a2f9d144de83
Autor:
Petra P. Larsen, MD, Catherine Féart, PhD, Jean-Paul Pais de Barros, PhD, Laure Gayraud, MSc, Marie-Noëlle Delyfer, MD, PhD, Jean-François Korobelnik, MD, Cédric Schweitzer, MD, PhD, Cécile Delcourt, PhD
Publikováno v:
Ophthalmology Science, Vol 5, Iss 1, Pp 100610- (2025)
Purpose: Lipopolysaccharide (LPS)-type endotoxins are naturally found in the gut microbiota and there is emerging evidence linking gut microbiota and neuroinflammation leading to retinal neurodegeneration. Thinning of the retinal nerve fiber layer (R
Externí odkaz:
https://doaj.org/article/7c73dcb7568741199aa54bc3be1d0e70
Autor:
Maxime Nguyen, Alain Putot, David Masson, Yves Cottin, Thomas Gautier, Laura Tribouillard, Anne-Laure Rérole, Pierre-Grégoire Guinot, Maud Maza, Jean-Paul Pais de Barros, Valérie Deckert, Michel Farnier, Laurent Lagrost, Marianne Zeller
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
BackgroundThere is increasing evidence regarding the association between endotoxemia and the pathogenesis of atherosclerosis and myocardial infarction (MI). During the acute phase of MI, endotoxemia might increase inflammation and drive adverse cardi
Externí odkaz:
https://doaj.org/article/123c9002e7f048d9860e8dce45bf2147
Autor:
Samah Maaloul, Imen Ghzaiel, Maher Mahmoudi, Hédi Mighri, Vivien Pires, Anne Vejux, Lucie Martine, Jean-Paul Pais de Barros, Emmanuelle Prost-Camus, Fayçal Boughalleb, Gérard Lizard, Raoudha Abdellaoui
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0304021 (2024)
Milk thistle seed oil is still not a well-known edible oil. Silybum marianum (milk thistle), is present in several countries and is the only known representative of the genus Silybum. However, Silybum eburneum, which is an endemic plant in Spain, Ken
Externí odkaz:
https://doaj.org/article/357d207223bc46d2b8949b520108cbe5
Autor:
Trinh-Le-Vi Kieu, Léa Pierre, Valentin Derangère, Sabrina Perrey, Caroline Truntzer, Antoine Jalil, Sébastien Causse, Emma Groetz, Adélie Dumont, Laura Guyard, Laurent Arnould, Jean-Paul Pais de Barros, Lionel Apetoh, Cédric Rébé, Emeric Limagne, Tony Jourdan, Laurent Demizieux, David Masson, Charles Thomas, François Ghiringhelli, Mickaël Rialland
Publikováno v:
Cell Death and Disease, Vol 13, Iss 9, Pp 1-18 (2022)
Abstract Metastatic breast cancer cannot be cured, and alteration of fatty acid metabolism contributes to tumor progression and metastasis. Here, we were interested in the elongation of very long-chain fatty acids protein 5 (Elovl5) in breast cancer.
Externí odkaz:
https://doaj.org/article/e46e8fef42814a68866b78b5481c0414
Autor:
Maxime Nguyen, Abderrahmane Bourredjem, Lionel Piroth, Bélaïd Bouhemad, Antoine Jalil, Gaetan Pallot, Naig Le Guern, Charles Thomas, Thomas Pilot, Victoria Bergas, Hélène Choubley, Jean-Pierre Quenot, Pierre-Emmanuel Charles, Laurent Lagrost, Valerie Deckert, Jean-Paul Pais de Barros, Pierre-Grégoire Guinot, David Masson, Christine Binquet, Thomas Gautier, Mathieu Blot, Lymphonie study group
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract COVID-19 pneumonia has specific features and outcomes that suggests a unique immunopathogenesis. Severe forms of COVID-19 appear to be more frequent in obese patients, but an association with metabolic disorders is not established. Here, we
Externí odkaz:
https://doaj.org/article/97f18805af9645668ad7756794ccc87c
Autor:
Mathieu Blot, Marine Jacquier, Ludwig-Serge Aho Glele, Guillaume Beltramo, Maxime Nguyen, Philippe Bonniaud, Sebastien Prin, Pascal Andreu, Belaid Bouhemad, Jean-Baptiste Bour, Christine Binquet, Lionel Piroth, Jean-Paul Pais de Barros, David Masson, Jean-Pierre Quenot, Pierre-Emmanuel Charles, Pneumochondrie study group
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-15 (2020)
Abstract Background COVID-19-related ARDS has unique features when compared with ARDS from other origins, suggesting a distinctive inflammatory pathogenesis. Data regarding the host response within the lung are sparse. The objective is to compare alv
Externí odkaz:
https://doaj.org/article/9317c93fd0e747da8c1bcba552f1ffd7
Autor:
Jaakko Leskelä, Iiro Toppila, Mari‐Anne Härma, Teemu Palviainen, Aino Salminen, Niina Sandholm, Milla Pietiäinen, Elisa Kopra, Jean‐Paul Pais de Barros, Mariann I. Lassenius, Anmol Kumar, Valma Harjutsalo, Kajsa Roslund, Carol Forsblom, Anu Loukola, Aki S. Havulinna, Laurent Lagrost, Veikko Salomaa, Per‐Henrik Groop, Markus Perola, Jaakko Kaprio, Markku Lehto, Pirkko J. Pussinen
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 21 (2021)
Background Translocation of lipopolysaccharide from gram‐negative bacteria into the systemic circulation results in endotoxemia. In addition to acute infections, endotoxemia is detected in cardiometabolic disorders, such as cardiovascular diseases
Externí odkaz:
https://doaj.org/article/631a7c96918a4e1398895d424f664db8
Autor:
Didier Payen, Claire Dupuis, Valérie Deckert, Jean-Paul Pais de Barros, Anne-Laure Rérole, Anne-Claire Lukaszewicz, Remi Coudroy, René Robert, Laurent Lagrost
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Objectives: To investigate the association of plasma LPS mass with mortality and inflammation in patients with peritonitis-induced septic shock (SS).Design: Longitudinal endotoxin and inflammatory parameters in a multicentric cohort of SS.Patients: P
Externí odkaz:
https://doaj.org/article/21e4a7e352c6439db84368edff96b878
Autor:
François Hermetet, Anne Buffière, Aziza Aznague, Jean-Paul Pais de Barros, Jean-Noël Bastie, Laurent Delva, Ronan Quéré
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
High fat diets (HFD) are thought to perturb murine hematopoiesis as a result of obesity. Here the authors find that short-term HFD reduces hematopoietic stem cells (HSC), disrupts lipid rafts and TGF-β1 signalling. Injecting HFD-fed mice with recomb
Externí odkaz:
https://doaj.org/article/3e421fb436c9409f853e3bfaa2e091f0