Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jean-Paul Laulin"'
Autor:
Emilie Laboureyras, Frédéric Aubrun, Maud Monsaingeon, Jean-Benoît Corcuff, Jean-Paul Laulin, Guy Simonnet
Publikováno v:
Pain Research and Management, Vol 19, Iss 4, Pp 191-197 (2014)
BACKGROUND: Opioid-induced hyperalgesia (OIH) is a recognized complication of opioid use that may facilitate the development of exaggerated postoperative pain.
Externí odkaz:
https://doaj.org/article/ebe24c695771456aa9020216733d023b
Autor:
Guy Simonnet, Jean-Benoît Corcuff, Frédéric Aubrun, Emilie Laboureyras, Jean-Paul Laulin, Maud Monsaingeon
Publikováno v:
Pain Research and Management, Vol 19, Iss 4, Pp 191-197 (2014)
BACKGROUND: Opioid-induced hyperalgesia (OIH) is a recognized complication of opioid use that may facilitate the development of exaggerated postoperative pain.OBJECTIVE: To examine the role of genetic factors on OIH by comparing four rat strains. Bec
Publikováno v:
Pharmacology Biochemistry and Behavior. 103:510-519
In humans, hyperalgesia, tolerance and anxiety disorders are common symptoms during heroin withdrawal syndrome. Significant evidence supports a role of NMDA receptors in these phenomena. Because polyamines may positively modulate the functioning of N
Autor:
Guy Simonnet, Jean-Paul Laulin, Stéphanie Gavello-Baudy, Chloé Le Roy, Emilie Laboureyras, Jérémy Chateauraynaud
Publikováno v:
The Journal of Pain. 12:1069-1079
Although stress induces analgesia, there is evidence that stressful events may exacerbate pain syndromes. Here, we studied the effects of 1 to 3 prestressful events (days 0, 2, and 7), such as non-nociceptive environmental stress, on inflammatory hyp
Publikováno v:
The Journal of Pain. 11:13-23
Using the rat chronic constriction injury (CCI) pain model, we evaluated whether nitrous oxide (N 2 O), a gas shown to have potent anti-hyperalgesic properties, may alleviate neuropathic pain. Mechanical nociceptive threshold was estimated using the
Autor:
Bertrand Rivalan, Gérard Janvier, Guy Simonnet, Jean Paul Laulin, Cyril Rivat, Philippe Richebé, Pierre Maurette
Publikováno v:
Canadian Journal of Anesthesia/Journal canadien d'anesthésie. 56:126-135
Opioids are widely used for anesthesia but paradoxically induce postoperative pain hypersensitivity via N-methyl-d-aspartate (NMDA) receptor modulation. Sevoflurane effects on opioid-induced hyperalgesia have not been yet evaluated in vivo. Neverthel
Autor:
Emilie Laboureyras, Jean Paul Laulin, Guy Simonnet, Havouis R, Florence Noble, Philippe Richebé, J.-P. Moulinoux, Cyril Rivat
Publikováno v:
Pain. 137:125-137
There is a compelling body of evidence that N-methyl-d-aspartate receptors (NMDA-R) play a critical role in the development and maintenance of pain hypersensitivity. However, long-term treatments with NMDA-R antagonists are limited by unacceptable si
Autor:
Marc Lemaire, Jean Paul Laulin, Philippe Richebé, Guy Simonnet, Cyril Rivat, Cyril Creton, Pierre Maurette
Publikováno v:
Anesthesiology. 103:845-854
Background Although opioids are unsurpassed analgesics for surgery, they also induce an N-methyl-D-aspartate-dependent enhancement of postoperative hyperalgesia. Because nitrous oxide (N2O) has anti-N-methyl-D-aspartate properties, the purpose of thi
Publikováno v:
Anesthesiology. 102:421-428
Background Although opioids are unsurpassed analgesics, experimental and clinical studies suggest that opioids activate N-methyl-d-aspartate pronociceptive systems leading to pain hypersensitivity and short-term tolerance. Because it is difficult in
Autor:
Jean-Paul Laulin, Guy Simonnet, Marcel Chauvin, Pierre Maurette, Cyril Rivat, Jean-Benoît Corcuff
Publikováno v:
Anesthesia & Analgesia. 94:1263-1269
Perioperative opioids increase postoperative pain and morphine requirement, suggesting acute opioid tolerance. Furthermore, opioids elicit N-methyl-D-aspartate (NMDA)-dependent pain hypersensitivity. We investigated postfentanyl morphine analgesic ef