Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Jean-Paul Issartel"'
Autor:
Matthieu Meryet-Figuiere, Mégane Vernon, Mamy Andrianteranagna, Bernard Lambert, Célia Brochen, Jean-Paul Issartel, Audrey Guttin, Pascal Gauduchon, Emilie Brotin, Florent Dingli, Damarys Loew, Nicolas Vigneron, Anaïs Wambecke, Edwige Abeilard, Emmanuel Barillot, Laurent Poulain, Loredana Martignetti, Christophe Denoyelle
Publikováno v:
Cancers, Vol 13, Iss 16, p 3970 (2021)
The identification of miRNAs’ targets and associated regulatory networks might allow the definition of new strategies using drugs whose association mimics a given miRNA’s effects. Based on this assumption we devised a multi-omics approach to prec
Externí odkaz:
https://doaj.org/article/11e926ab40b840498bae9039620f1c7c
Autor:
Nicolas Vigneron, Matthieu Meryet-Figuière, Audrey Guttin, Jean-Paul Issartel, Bernard Lambert, Mélanie Briand, Marie-Hélène Louis, Mégane Vernon, Pierre Lebailly, Yannick Lecluse, Florence Joly, Sophie Krieger, Stéphanie Lheureux, Bénédicte Clarisse, Alexandra Leconte, Pascal Gauduchon, Laurent Poulain, Christophe Denoyelle
Publikováno v:
Molecular Oncology, Vol 10, Iss 7, Pp 981-992 (2016)
Circulating miRNAs are promising biomarkers in oncology but have not yet been implemented in the clinic given the lack of concordance across studies. In order to increase the cross‐studies reliability, we attempted to reduce and to control the circ
Externí odkaz:
https://doaj.org/article/a12f7c763bef444c973543d6bcaefa4e
Autor:
Elodie Lages, Audrey Guttin, Michèle El Atifi, Claire Ramus, Hélène Ipas, Isabelle Dupré, Delphine Rolland, Caroline Salon, Catherine Godfraind, Florence deFraipont, Mehdi Dhobb, Laurent Pelletier, Didier Wion, Emmanuel Gay, François Berger, Jean-Paul Issartel
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20600 (2011)
Gliomas such as oligodendrogliomas (ODG) and glioblastomas (GBM) are brain tumours with different clinical outcomes. Histology-based classification of these tumour types is often difficult. Therefore the first aim of this study was to gain microRNA d
Externí odkaz:
https://doaj.org/article/c0e295e372cf4ce2b732297070d422f1
Autor:
Ali Bouamrani, Claire Ramus, Emmanuel Gay, Laurent Pelletier, Myriam Cubizolles, Sabine Brugière, Didier Wion, François Berger, Jean-Paul Issartel
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9238 (2010)
BackgroundTissue invasion or tissue infiltration are clinical behaviors of a poor-prognosis subset of meningiomas. We carried out proteomic analyses of tissue extracts to discover new markers to accurately distinguish between infiltrative and noninfi
Externí odkaz:
https://doaj.org/article/3c2f47059bd447df87fa28acbc6599f7
Autor:
Rémy Sadoul, Mathieu Meunier, Karine Laulagnier, Jean-Paul Issartel, Sylvie Tondeur, Sophie Park, Claire Jouzier, Quentin Testard, Audrey Guttin, Christine Lefebvre, Sarah Ancelet, Christine Chatellard, Julien Thevenon, Pierre Hainaut, Virginie Persoons, Benoît Polack, Johanna Zannoni, Jean-François Deleuze, Jean-Yves Cahn, Florent Chuffart, Mylène Pezet, Sophie Rousseaux, David Laurin, Karin Pernet-Gallay
Publikováno v:
Leukemia
Leukemia, 2020, 34 (8), pp.2249-2253. ⟨10.1038/s41375-020-0738-8⟩
Leukemia, 2020, 34 (8), pp.2249-2253. ⟨10.1038/s41375-020-0738-8⟩
International audience; Physiopathology of myelodysplastic syndrome (MDS) remains poorly understood and the role of the microenvironment is increasingly highlighted. Recent studies in mouse models demonstrate that abnormalities of mesenchymal stromal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67fccb1d3a111aeea1ee87d53d18f843
https://hal.science/hal-03969633
https://hal.science/hal-03969633
Autor:
Mamy Andrianteranagna, Emilie Brotin, Emmanuel Barillot, Mégane Vernon, Edwige Abeilard, Loredana Martignetti, Nicolas Vigneron, Jean-Paul Issartel, Damarys Loew, Célia Brochen, Anaïs Wambecke, Matthieu Meryet-Figuière, Florent Dingli, Pascal Gauduchon, Audrey Guttin, Christophe Denoyelle, Laurent Poulain, Bernard Lambert
Publikováno v:
Cancers, Vol 13, Iss 3970, p 3970 (2021)
Cancers
Volume 13
Issue 16
Cancers
Volume 13
Issue 16
Simple Summary The re-introduction of miRNAs with tumor-suppressor activity in cancer cells has not yet been implemented in clinical practice yet. However, the identification of miRNAs’ targets and associated regulatory networks might allow the def
Autor:
Jean-Paul Issartel, Shubaash Anthiya, Emmanuel Garcion, Audrey Griveau, Martin C. Garnett, Patrick Baril, Claire Loussouarn
Publikováno v:
Trends in Cancer
Trends in Cancer, Cell Press, 2018, 4 (3), pp.222-238. ⟨10.1016/j.trecan.2017.12.008⟩
Trends in Cancer, 2018, 4 (3), pp.222-238. ⟨10.1016/j.trecan.2017.12.008⟩
Trends in Cancer, Cell Press, 2018, 4 (3), pp.222-238. ⟨10.1016/j.trecan.2017.12.008⟩
Trends in Cancer, 2018, 4 (3), pp.222-238. ⟨10.1016/j.trecan.2017.12.008⟩
Shubaash ANTHIYA and Audrey GRIVEAU contributed equally to this work.; International audience; MicroRNAs (miRNAs) are key regulatory elements coded by the genome. A single miRNA can downregulate expression of multiple genes involved in diverse functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67366f5ae13903b2386d3687ce1925f8
https://www.hal.inserm.fr/inserm-01691531
https://www.hal.inserm.fr/inserm-01691531
Autor:
Didier Wion, Jean-Paul Issartel, Boudewijn van der Sanden, François Berger, Laurent Selek, Florence Appaix
Publikováno v:
Future Oncology. 9:817-824
Viewing tumors as ecosystems offers the opportunity to consider how ecological concepts can be translated to novel therapeutic perspectives. The ecological trap concept emerged approximately half a century ago when it was observed that animals can pr
Autor:
Jean-Paul Issartel, Audrey Guttin, Laurent Poulain, Yannick Lecluse, Pierre Lebailly, Matthieu Meryet-Figuière, Bénédicte Clarisse, Mélanie Briand, Nicolas Vigneron, Stephanie Lheureux, Marie-Hélène Louis, Bernard Lambert, Florence Joly, Christophe Denoyelle, Pascal Gauduchon, Sophie Krieger, Mégane Vernon, Alexandra Leconte
Publikováno v:
Molecular Oncology
Molecular Oncology, Elsevier, 2016, 10 (7), pp.981-992. ⟨10.1016/j.molonc.2016.03.005⟩
Molecular Oncology, 2016, 10 (7), pp.981-992. ⟨10.1016/j.molonc.2016.03.005⟩
Molecular Oncology, Elsevier, 2016, 10 (7), pp.981-992. ⟨10.1016/j.molonc.2016.03.005⟩
Molecular Oncology, 2016, 10 (7), pp.981-992. ⟨10.1016/j.molonc.2016.03.005⟩
Circulating miRNAs are promising biomarkers in oncology but have not yet been implemented in the clinic given the lack of concordance across studies. In order to increase the cross‐studies reliability, we attempted to reduce and to control the circ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8861bce40b8773a1ccc206147f0f66eb
https://www.hal.inserm.fr/inserm-02304791/document
https://www.hal.inserm.fr/inserm-02304791/document
Autor:
Hélène Ipas, Maud Barbado, Jean-Paul Issartel, Emmanuel Garcion, Audrey Guttin, Catherine Mouret
Publikováno v:
MicroRNA (Shariqah, United Arab Emirates).
Objective: microRNA assessments in biological samples can be performed by different methods that mainly rely on hybridization process, qPCR or RNA sequencing. With the aim to detect and validate microRNA biomarkers in tumor samples, we challenged the