Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Jean-Pascal Capp"'
Publikováno v:
Translational Oncology, Vol 49, Iss , Pp 102069- (2024)
A common feature of bacterial, fungal and cancer cell populations upon treatment is the presence of tolerant and persistent cells able to survive, and sometimes grow, even in the presence of usually inhibitory or lethal drug concentrations, driven by
Externí odkaz:
https://doaj.org/article/29d4f1f45d604601b38e40f3aed0eb8a
Autor:
Margaux Bieuville, Antoine M. Dujon, Nynke Raven, Beata Ujvari, Pascal Pujol, Zahra Eslami‐S, Catherine Alix Panabières, Jean‐Pascal Capp, Frédéric Thomas
Publikováno v:
Evolutionary Applications, Vol 17, Iss 10, Pp n/a-n/a (2024)
ABSTRACT While it is recognised that most, if not all, multicellular organisms harbour neoplastic processes within their bodies, the timing of when these undesirable cell proliferations are most likely to occur and progress throughout the organism's
Externí odkaz:
https://doaj.org/article/445f193a96254655b66f0ed346012130
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
The genetic stability and metabolic robustness of production strains is one of the key criteria for the production of bio-based products by microbial fermentation on an industrial scale. These criteria were here explored in an industrial ethanol-prod
Externí odkaz:
https://doaj.org/article/0b022c6f2a914a64b8e66b964dae9360
Autor:
Sophie Tissot, Lena Guimard, Jordan Meliani, Justine Boutry, Antoine M. Dujon, Jean-Pascal Capp, Jácint Tökölyi, Peter A. Biro, Christa Beckmann, Laura Fontenille, Nam Do Khoa, Rodrigo Hamede, Benjamin Roche, Beata Ujvari, Aurora M. Nedelcu, Frédéric Thomas
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract The inability to control cell proliferation results in the formation of tumors in many multicellular lineages. Nonetheless, little is known about the extent of conservation of the biological traits and ecological factors that promote or inhi
Externí odkaz:
https://doaj.org/article/cd26f6fe69714f7291b2d87a33327d20
Autor:
Jean‐Pascal Capp, Frédéric Thomas, Andriy Marusyk, Antoine M. Dujon, Sophie Tissot, Robert Gatenby, Benjamin Roche, Beata Ujvari, James DeGregori, Joel S. Brown, Aurora M. Nedelcu
Publikováno v:
Evolutionary Applications, Vol 16, Iss 7, Pp 1239-1256 (2023)
Abstract It is traditionally assumed that during cancer development, tumor cells abort their initially cooperative behavior (i.e., cheat) in favor of evolutionary strategies designed solely to enhance their own fitness (i.e., a “selfish” life sty
Externí odkaz:
https://doaj.org/article/40f663a816d647f3bbcfcd57342f99de
Autor:
Sophie Tissot, Lena Guimard, Jordan Meliani, Justine Boutry, Antoine M. Dujon, Jean-Pascal Capp, Jácint Tökölyi, Peter A. Biro, Christa Beckmann, Laura Fontenille, Nam Do Khoa, Rodrigo Hamede, Benjamin Roche, Beata Ujvari, Aurora M. Nedelcu, Frédéric Thomas
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/5a5a1668f4a3435a91fd0e219ea5b6dc
Publikováno v:
Current Research in Food Science, Vol 7, Iss , Pp 100603- (2023)
Non-conventional yeast species, or non-Saccharomyces yeasts, are increasingly recognized for their involvement in fermented foods. Many of them exhibit probiotic characteristics that are mainly due to direct contacts with other cell types through var
Externí odkaz:
https://doaj.org/article/8de3d9762b1644198fb95ac8dd81688e
The Ins and Outs of Endosteal Niche Disruption in the Bone Marrow: Relevance for Myeloma Oncogenesis
Autor:
Jean-Pascal Capp, Régis Bataille
Publikováno v:
Biology, Vol 12, Iss 7, p 990 (2023)
Multiple Myeloma (MM) and its preexisting stage, termed Monoclonal Gammopathy of Undetermined Significance (MGUS), have long been considered mainly as genomic diseases. However, the bone changes observed in both conditions have led to a reassessment
Externí odkaz:
https://doaj.org/article/926e08a9fb7e4a5380691817168387e9
Autor:
Jean‐Pascal Capp
Publikováno v:
Evolutionary Applications, Vol 14, Iss 4, Pp 893-901 (2021)
Abstract Genetic variability, epigenetic variability, and gene expression variability (noise) are generally considered independently in their relationship with phenotypic variation. However, they appear to be intrinsically interconnected and influenc
Externí odkaz:
https://doaj.org/article/0773860560fe49cb8e59c047a5990253
Autor:
Antoine M. Dujon, Athena Aktipis, Catherine Alix‐Panabières, Sarah R. Amend, Amy M. Boddy, Joel S. Brown, Jean‐Pascal Capp, James DeGregori, Paul Ewald, Robert Gatenby, Marco Gerlinger, Mathieu Giraudeau, Rodrigo K. Hamede, Elsa Hansen, Irina Kareva, Carlo C. Maley, Andriy Marusyk, Nicholas McGranahan, Michael J. Metzger, Aurora M. Nedelcu, Robert Noble, Leonard Nunney, Kenneth J. Pienta, Kornelia Polyak, Pascal Pujol, Andrew F. Read, Benjamin Roche, Susanne Sebens, Eric Solary, Kateřina Staňková, Holly Swain Ewald, Frédéric Thomas, Beata Ujvari
Publikováno v:
Evolutionary Applications, Vol 14, Iss 4, Pp 877-892 (2021)
Abstract The application of evolutionary and ecological principles to cancer prevention and treatment, as well as recognizing cancer as a selection force in nature, has gained impetus over the last 50 years. Following the initial theoretical approach
Externí odkaz:
https://doaj.org/article/89d15c8bc6dc4e8fb594eb56f0fd801f