Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Jean-Michel Wieruszeski"'
Autor:
Pierre Lebrun, Dominique Raze, Bernd Fritzinger, Jean-Michel Wieruszeski, Franck Biet, Alexander Dose, Mathieu Carpentier, Dirk Schwarzer, Fabrice Allain, Guy Lippens, Camille Locht
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32421 (2012)
BackgroundTuberculosis remains one of the most important causes of global mortality and morbidity, and the molecular mechanisms of the pathogenesis are still incompletely understood. Only few virulence factors of the causative agent Mycobacterium tub
Externí odkaz:
https://doaj.org/article/38999e142a404dbb8646e8d32f28d108
Autor:
Isabelle Landrieu, Caroline Smet-Nocca, Laziza Amniai, Justin Vijay Louis, Jean-Michel Wieruszeski, Jozef Goris, Veerle Janssens, Guy Lippens
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21521 (2011)
Tau phosphorylation and dephosphorylation regulate in a poorly understood manner its physiological role of microtubule stabilization, and equally its integration in Alzheimer disease (AD) related fibrils. A specific phospho-pattern will result from t
Externí odkaz:
https://doaj.org/article/21141210c88a435cac1fad79244717ea
Autor:
Puneet Ahuja, Guy Lippens, Caroline Smet, Jean-Michel Wieruszeski, Juan José Marín López, Xavier Hanoulle, Isabelle Landrieu, François-Xavier Cantrelle, Isabelle Huvent
Publikováno v:
Journal of Molecular Biology
Journal of Molecular Biology, Elsevier, 2016, 428 (1), pp.79-91. ⟨10.1016/j.jmb.2015.11.023⟩
Journal of Molecular Biology, 2016, 428 (1), pp.79-91. ⟨10.1016/j.jmb.2015.11.023⟩
Journal of Molecular Biology, Elsevier, 2016, 428 (1), pp.79-91. ⟨10.1016/j.jmb.2015.11.023⟩
Journal of Molecular Biology, 2016, 428 (1), pp.79-91. ⟨10.1016/j.jmb.2015.11.023⟩
The conformational state of distinct prolines can determine the folding of a protein but equally other biological processes when coupled to a conformation-sensitive secondary reaction. For the neuronal tau protein, the importance of proline conformat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9270850782c0c603c19798dbd47460f1
https://hal.archives-ouvertes.fr/hal-01389832
https://hal.archives-ouvertes.fr/hal-01389832
Autor:
Nathalie Sibille, Dries Verdegem, Laziza Amniai, Jean-Michel Wieruszeski, Guy Lippens, Caroline Fauquant, Isabelle Landrieu, Isabelle Huvent, Arnaud Leroy
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 80:454-462
Phosphorylation of the neuronal Tau protein is implicated in both the regulation of its physiological function of microtubule stabilization and its pathological propensity to aggregate into the fibers that characterize Alzheimer's diseased neurons. H
Autor:
Jean-Marc Nuzillard, Alexandre Martinez, Jean-Michel Wieruszeski, Séverine Tisse, Damien Jeannerat, Jean-Philippe Bouillon, F. Pilard, Bertrand Plainchont, Guy Lippens
Publikováno v:
Magnetic Resonance in Chemistry. 49:781-787
The complete assignment of the 1H and 13C sugar resonances in mono-3,6-anhydro-heptakis(2,3-O-methyl)-hexakis(6-O-methyl)-β-cyclodextrin, an asymmetrically functionalized β-cyclodextrin, was carried out by means of 2D NMR experiments. The TOCSY and
Autor:
Davy Sinnaeve, Els J.M. Van Damme, Jean-Michel Wieruszeski, Christophe Ampe, Gianni Vandenborre, José C. Martins, Katelijne Gheysen, Guy Lippens, Bernd Fritzinger, David Bourry
Publikováno v:
Magnetic Resonance in Chemistry. 49:9-15
We present the use of 1-mm room-temperature probe technology to perform intermolecular interaction studies using chemical shift perturbation methods and saturation transfer difference (STD) spectroscopy using small sample volumes. The use of a small
Autor:
Ralf Bartenschlager, Xavier Hanoulle, Guy Lippens, Aurélie Badillo, Jean-Michel Wieruszeski, François Penin, Isabelle Landrieu, Dries Verdegem
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2009, epub ahead of print. ⟨10.1074/jbc.M809244200⟩
Journal of Biological Chemistry, 2009, epub ahead of print. ⟨10.1074/jbc.M809244200⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2009, epub ahead of print. ⟨10.1074/jbc.M809244200⟩
Journal of Biological Chemistry, 2009, epub ahead of print. ⟨10.1074/jbc.M809244200⟩
International audience; We report a biochemical and structural characterization of domain 2 of the non-structural 5A protein (NS5A) from the JFH1 Hepatitis C virus strain and its interactions with Cyclophilins A and B (CypA and CypB). Gel filtration
Autor:
Danièle Wouters, Guy Lippens, André Tartar, Pierre Sautière, Eric Buisine, Jean-Michel Wieruszeski
Publikováno v:
The Journal of Peptide Research. 49:545-555
To extend our knowledge about the structural features of short scorpion toxins, the ion-exchange fractions obtained from Leiurus quinquestriatus hebraeus venom were investigated by plasma desorption mass spectrometry in order to select low molecular
Autor:
Gérard Strecker, Jean-Michel Wieruszeski, Yves Plancke, Marie-Dominique Fontaine, Florence Delplace
Publikováno v:
European Journal of Biochemistry. 231:424-433
TheO-linked acidic oligosaccharides of the jelly coat surrounding the eggs of Ambystoma maculatum were analyzed by NMR spectroscopy. The structures of the major oligosaccharides were established as follows where Kdn represents 3-deoxy-d-glycero-d-gal
Publikováno v:
Biochemistry. 47:6519-6530
Thymine-DNA glycosylases (TDGs) initiate base excision repair by debasification of the erroneous thymine or uracil nucleotide in G.T and G.U mispairs which arise at high frequency through spontaneous or enzymatic deamination of methylcytosine and cyt