Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Jean-Michel Mesnard"'
Autor:
Julie Tram, Laetitia Marty, Célima Mourouvin, Magali Abrantes, Ilham Jaafari, Raymond Césaire, Philippe Hélias, Benoit Barbeau, Jean-Michel Mesnard, Véronique Baccini, Laurent Chaloin, Jean-Marie Jr. Peloponese
Publikováno v:
Cells, Vol 13, Iss 18, p 1517 (2024)
Human endogenous retroviruses (HERVs) are retroviral sequences integrated into 8% of the human genome resulting from ancient exogenous retroviral infections. Unlike endogenous retroviruses of other mammalian species, HERVs are mostly replication and
Externí odkaz:
https://doaj.org/article/848c66f8008e4eddb3a76bc707f2f30d
Autor:
Zhenlong Liu, Émilie Larocque, Yongli Xie, Yong Xiao, Guy Lemay, Jean-Marie Peloponese, Jean-Michel Mesnard, Éric Rassart, Rongtuan Lin, Shuang Zhou, Yiming Zeng, Hongzhi Gao, Shan Cen, Benoit Barbeau
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Human T-cell leukemia virus type 1 is the causative agent of HTLV-1-associated myelopathy/tropical spastic paraparesis and adult T-cell leukemia-lymphoma (ATL). The HTLV-1 basic leucine zipper factor (HBZ) has been associated to the cancer-inducing p
Externí odkaz:
https://doaj.org/article/0f8ce197a8284805aad65f31716bb1d0
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Eukaryotic cells employ a broad range of mechanisms to regulate gene expression. Among others, mRNA alternative splicing is a key process. It consists of introns removal from an immature mRNA (pre-mRNA) via a transesterification reaction to create a
Externí odkaz:
https://doaj.org/article/8703d2ca7ce04ac0acc9a49bcbaa7f48
Autor:
Masao Matsuoka, Jean-Michel Mesnard
Publikováno v:
Retrovirology, Vol 17, Iss 1, Pp 1-8 (2020)
Abstract Human T cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia-lymphoma (ATL) and inflammatory diseases. The HTLV-1 bZIP factor (HBZ) gene is constantly expressed in HTLV-1 infected cells and ATL cells. HBZ protein suppresses trans
Externí odkaz:
https://doaj.org/article/fe0f1c3e10b8437f9878e8cd98dec186
Publikováno v:
Frontiers in Microbiology, Vol 11 (2021)
It was first predicted in 1988 that there may be an Open Reading Frame (ORF) on the negative strand of the Human Immunodeficiency Virus type 1 (HIV-1) genome that could encode a protein named AntiSense Protein (ASP). In spite of some controversy, rep
Externí odkaz:
https://doaj.org/article/07e586ea1e064bc6864829f6a3763a7f
A Pilot Study of the Humoral Response Against the AntiSense Protein (ASP) in HIV-1-Infected Patients
Autor:
Juliette Savoret, Nathalie Chazal, Jean-Pierre Moles, Edouard Tuaillon, Faroudy Boufassa, Laurence Meyer, Camille Lecuroux, Olivier Lambotte, Philippe Van De Perre, Jean-Michel Mesnard, Antoine Gross
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
The existence of an antisense Open Reading Frame (ORF) that encodes a putative AntiSense Protein (ASP) on the proviral genome of Human Immunodeficiency Virus type 1 (HIV-1) was a source of debate for 30 years. During the last years, some progresses h
Externí odkaz:
https://doaj.org/article/971218b1fe2047a1891b738c50628d75
Autor:
Christophe Chopard, Phuoc Bao Viet Tong, Petra Tóth, Malvina Schatz, Hocine Yezid, Solène Debaisieux, Clément Mettling, Antoine Gross, Martine Pugnière, Annie Tu, Jean-Marc Strub, Jean-Michel Mesnard, Nicolas Vitale, Bruno Beaumelle
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
It is not clear whether and how incoming HIV-1 Tat accumulates in uninfected cells. Here, Chopard et al. show that, in uninfected cells, incoming Tat is palmitoylated on Cys31 by DHHC-20, which increases its affinity for PI(4,5)P2 and results in its
Externí odkaz:
https://doaj.org/article/0b76da00f3d140a9bf12b239560dc94a
Publikováno v:
Viruses, Vol 13, Iss 11, p 2221 (2021)
Paradigm shifts throughout the history of microbiology have typically been ignored, or met with skepticism and resistance, by the scientific community. This has been especially true in the field of virology, where the discovery of a “contagium vivu
Externí odkaz:
https://doaj.org/article/fe20ad6a1cfa442baed2645511361d7f
Publikováno v:
Viruses, Vol 7, Iss 12, Pp 6490-6505 (2015)
More than thirty years have passed since human T-cell leukemia virus type 1 (HTLV-1) was described as the first retrovirus to be the causative agent of a human cancer, adult T-cell leukemia (ATL), but the precise mechanism behind HTLV-1 pathogenesis
Externí odkaz:
https://doaj.org/article/04ba204199c448df9edca5fc1bf44978
Publikováno v:
Frontiers in Microbiology, Vol 8 (2018)
Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of a fatal malignancy known as adult T-cell leukemia (ATL). One way to address the pathology of the disease lies on conducting research with a molecular approach. In addition to the a
Externí odkaz:
https://doaj.org/article/59527e9fc2a14344926f88160fe9d25d