Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jean-Michel Gaullier"'
Autor:
Steinar Aamdal, Hilary Thomas, Marit Liland Sandvold, Michael J. Lind, Svein Dueland, Jean Michel Gaullier, Wenche Rasch
Publikováno v:
Acta Oncologica. 48:137-145
Purpose. Cytarabine (ara-C) has limited activity in solid tumours. CP-4055 (ELACYT TM ) is a novel ara-C-5’-elaidic acid ester that may circumvent this limitation. CP-4055 maximum tolerated dose (MTD), pharmacokinetics and antitumor activity have b
Autor:
Minna Nurminiemi, Johan Halse, Kjetil Høye, Hans Olav Høivik, Marianne O'Shea, Cecilie Hassfeld, Christian Syvertsen, Ola Gudmundsen, Alexandra W. C. Einerhand, Jean-Michel Gaullier
Publikováno v:
British Journal of Nutrition. 97:550-560
Long-term supplementation with conjugated linoleic acid (CLA) reduces body fat mass (BFM) and increases or maintains lean body mass (LBM). However, the regional effect of CLA was not studied. The study aimed to evaluate the effect of CLA per region a
Publikováno v:
Journal of Biological Chemistry. 275:24595-24600
FYVE zinc finger domains, which are conserved in multiple proteins from yeast to man, interact specifically with the membrane lipid phosphatidylinositol 3-phosphate (PtdIns(3)P). Here we have investigated the structural requirements for the interacti
Publikováno v:
Journal of Biological Chemistry. 274:28857-28860
The fusion of transport vesicles with their cognate target membranes, an essential event in intracellular membrane trafficking, is regulated by SNARE proteins and Rab GTPases. Rab GTPases are thought to act prior to SNAREs in vesicle docking, but the
Publikováno v:
Biochemical Society Transactions. 27:666-670
40 Auger, K, Serunian, L A., Soltofl S. P., Libby, P. and Cantley, Vanhaesebroeck B., Gout, I., Panayotou, G., Domin, J., Stein, R, Pages, F. et al. ( I 996) Philos. Trans. R SOC. London B 35 I , 2 17-223 38 Volinia, S., Dhand, R, Vanhaesebroeck B.,
Publikováno v:
Biochemical Journal. 338:539-543
EEA1, an early-endosomal protein originally identified as an autoantigen, is essential for endocytic membrane fusion. It interacts with early endosomes via binding to the membrane lipid phosphatidylinositol 3-phosphate (PtdIns3P) and the active form
Autor:
Harald Stenmark, Anne Simonsen, Ban-Hock Toh, Savvas Christoforidis, Andreas Brech, Jean Michel Gaullier, Marino Zerial, Carol Murphy, Roger Lippé, Judy M. Callaghan
Publikováno v:
Nature. 394:494-498
GTPases and lipid kinases regulate membrane traffic along the endocytic pathway by mechanisms that are not completely understood. Fusion between early endosomes requires phosphatidylinositol-3-OH kinase (PI(3)K) activity as well as the small GTPase R
Autor:
Trond Stokke, Johan Emelian Moan, Kristian Berg, Jean Michel Gaullier, Øystein Bech, Li Wei Ma, Harald Steen
Publikováno v:
International Journal of Cancer. 75:134-139
Human colon adenocarcinoma cells (WiDr) and Chinese hamster lung fibroblasts cells (V79) were incubated with different concentrations of 5-aminolevulinic acid (ALA), and the production of protoporphyrin IX (PpIX) was studied using several techniques.
Autor:
Cristina Sousa, Marc Geze, Jean-Michel Gaullier, René Santus, T. Sa e Melo, Jean-Claude Mazière
Publikováno v:
Photochemistry and Photobiology. 63:601-607
Neutral red is a lysosomal probe and a biological pH indicator. In aqueous solutions, the protonated (NRH) and neutral (NR) forms of monomeric neutral red exhibit distinct absorption maxima (535 and 450 nm, respectively) but have the same fluorescenc
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 30:195-200
The pyrrole-amino acid and peptide N -conjugates synthesized from tyrosine, histidine and glutathione very effectively quench the 1270 nm singlet oxygen luminescence, at rates ranging from 10 8 to 10 9 M −1 s −1 . Nuclear magnetic resonance spect