Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jean-Michel Auger"'
Autor:
Manel Ouji, Thibaud Reyser, Yoshiki Yamaryo-Botté, Michel Nguyen, David Rengel, Axelle Dutreuil, Marlène Marcellin, Odile Burlet-Schiltz, Jean-Michel Augereau, Michael K. Riscoe, Lucie Paloque, Cyrille Botté, Françoise Benoit-Vical
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 26, Iss , Pp 100565- (2024)
Emergence and spread of parasite resistance to artemisinins, the first-line antimalarial therapy, threaten the malaria eradication policy. To identify therapeutic targets to eliminate artemisinin-resistant parasites, the functioning of the apicoplast
Externí odkaz:
https://doaj.org/article/b391844e85f845208759c016652562e2
Autor:
Thibaud Reyser, Lucie Paloque, Jean-Michel Augereau, Luisa Di Stefano, Françoise Benoit-Vical
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-18 (2024)
Abstract Over the past thirty years, epigenetic regulation of gene expression has gained increasing interest as it was shown to be implicated in illnesses ranging from cancers to parasitic diseases. In the malaria parasite, epigenetics was shown to b
Externí odkaz:
https://doaj.org/article/115c82b28bb842faba686f282f9c6c18
Autor:
Ange W. Embo-Ibouanga, Michel Nguyen, Jean-Patrick Joly, Mathilde Coustets, Jean-Michel Augereau, Lucie Paloque, Nicolas Vanthuyne, Raphaël Bikanga, Anne Robert, Françoise Benoit-Vical, Gérard Audran, Philippe Mellet, Jérôme Boissier, Sylvain R. A. Marque
Publikováno v:
Pathogens, Vol 13, Iss 6, p 482 (2024)
The expansion of drug resistant parasites sheds a serious concern on several neglected parasitic diseases. Our recent results on cancer led us to envision the use of peptide-alkoxyamines as a highly selective and efficient new drug against schistosom
Externí odkaz:
https://doaj.org/article/6b44c96ba8b740f1bc5d87f4c77dc40f
Autor:
Ange W. Embo-Ibouanga, Michel Nguyen, Lucie Paloque, Mathilde Coustets, Jean-Patrick Joly, Jean-Michel Augereau, Nicolas Vanthuyne, Raphaël Bikanga, Naomie Coquin, Anne Robert, Gérard Audran, Jérôme Boissier, Philippe Mellet, Françoise Benoit-Vical, Sylvain R. A. Marque
Publikováno v:
Molecules, Vol 29, Iss 6, p 1397 (2024)
The emergence and spread of drug-resistant Plasmodium falciparum parasites shed a serious concern on the worldwide control of malaria, the most important tropical disease in terms of mortality and morbidity. This situation has led us to consider the
Externí odkaz:
https://doaj.org/article/bf0329fc0d8b4c23893774724d75ac89
Autor:
Thibaud Reyser, Lucie Paloque, Michel Nguyen, Jean-Michel Augereau, Matthew John Fuchter, Marie Lopez, Paola B. Arimondo, Storm Hassell-Hart, John Spencer, Luisa Di Stefano, Françoise Benoit-Vical
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2440 (2023)
The use of artemisinin and its derivatives has helped reduce the burden of malaria caused by Plasmodium falciparum. However, artemisinin-resistant parasites are able, in the presence of artemisinins, to stop their cell cycles. This quiescent state ca
Externí odkaz:
https://doaj.org/article/e04148a7b56b4e0794e981d27ef6714e
Autor:
Véronique Loyau, Alain Bonnefoy, Solange Gouin D'ambrieres, A Dussarat, Nicole Tessot, C. Fromentin, Sylvette Lachaud, Patrick Laurin, Jean-Michel Auger, Yannick Benedetti, Francois Bretin, J. F. Chantot, C. Agouridas, A. Denis, Le Martret Odile
Publikováno v:
Journal of Medicinal Chemistry. 41:4080-4100
In the search for new antibiotics active against macrolide-resistant pneumococci and Haemophilus influenzae, we synthesized a new class of 3-oxo-6-O-methylerythromycin derivatives, so-called "ketolides". A keto function was introduced in position 3 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec9a59ca094217e91a9cd1a14deb0276
https://doi.org/10.1021/jm980240d
https://doi.org/10.1021/jm980240d
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 1872 (2021)
Several measures are in place to combat the worldwide spread of malaria, especially in regions of high endemicity. In part, most common antimalarials, such as quinolines and artemisinin and its derivatives, deploy an ROS-mediated approach to kill mal
Externí odkaz:
https://doaj.org/article/d36eb2ccd30d4625a3a3f7bd96a08ca4
Autor:
Thibaud Reyser, Tung H. To, Chinedu Egwu, Lucie Paloque, Michel Nguyen, Alexandre Hamouy, Jean-Luc Stigliani, Christian Bijani, Jean-Michel Augereau, Jean-Patrick Joly, Julien Portela, Jeffrey Havot, Sylvain R. A. Marque, Jérôme Boissier, Anne Robert, Françoise Benoit-Vical, Gérard Audran
Publikováno v:
Molecules, Vol 25, Iss 17, p 3838 (2020)
Malaria and schistosomiasis are major infectious causes of morbidity and mortality in the tropical and sub-tropical areas. Due to the widespread drug resistance of the parasites, the availability of new efficient and affordable drugs for these endemi
Externí odkaz:
https://doaj.org/article/441453e549bb490ead870e29a378d8fb
Autor:
Manel Ouji, Guillaume Barnoin, Álvaro Fernández Álvarez, Jean-Michel Augereau, Catherine Hemmert, Françoise Benoit-Vical, Heinz Gornitzka
Publikováno v:
Molecules, Vol 25, Iss 12, p 2817 (2020)
The emergence of Plasmodium falciparum parasites, responsible for malaria disease, resistant to antiplasmodial drugs including the artemisinins, represents a major threat to public health. Therefore, the development of new antimalarial drugs or combi
Externí odkaz:
https://doaj.org/article/c69d09a16117434d96bdd6baaccbf70d
Autor:
Ioannis Tsamesidis, Chinedu O. Egwu, Pierre Pério, Jean-Michel Augereau, Françoise Benoit-Vical, Karine Reybier
Publikováno v:
Metabolites, Vol 10, Iss 5, p 175 (2020)
Red blood cells are constantly exposed to reactive species under physiological or pathological conditions or during administration of xenobiotics. Regardless of the source, its accurate quantification is paramount in the area of theragnostics, which
Externí odkaz:
https://doaj.org/article/6b0f37b31b3e45cfbc687369b2e4383f