Zobrazeno 1 - 10
of 299
pro vyhledávání: '"Jean-Marie PAGÈS"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract The sophisticated envelope of Gram-negative bacteria modulates the uptake of small molecules in a side-chain-sensitive manner. Despite intensive theoretical and experimental investigations, a general set of pathways underpinning antibiotic u
Externí odkaz:
https://doaj.org/article/4a71e6f973724f2a8c0d238afe3c63d0
Autor:
Julia Vergalli, Hugo Chauvet, Francesco Oliva, Jelena Pajović, Giuliano Malloci, Attilio Vittorio Vargiu, Matthieu Réfrégiers, Paolo Ruggerone, Jean-Marie Pagès
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
A competitive efflux assay combined with computational approaches reveal how different quinolones interact with the prototypical bacterial multidrug efflux transporter AcrB, providing insights which may help optimise antibiotics.
Externí odkaz:
https://doaj.org/article/9ea12524a8cd497c89d5c583e95f6c7d
Autor:
Muriel Masi, Julia Vergalli, Ishan Ghai, Andrea Barba-Bon, Thérèse Schembri, Werner M. Nau, Daniel Lafitte, Mathias Winterhalter, Jean-Marie Pagès
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
The translocation of cephalosporins across enterobacterial OmpF and OmpC channels is monitored in real-time, demonstrating differential permeation of some cephalosporins through OmpF and OmpC.
Externí odkaz:
https://doaj.org/article/39f80cd5a3274daa89bec7da2a783110
Autor:
René Dofini Magnini, Mathieu Nitiéma, Geoffroy G. Ouédraogo, Sylvain Ilboudo, Alimata Bancé, Hassanata Millogo-Koné, Carole Di Giorgio, Jean-Marie Pagès, Adama Hilou, Anne Davin-Regli
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Acacia senegal is a plant traditionally used for its various properties, including the treatment of infectious diseases. Recently, our team has demonstrated the ability of the hydroethanolic extract of the leaves to increase the a
Externí odkaz:
https://doaj.org/article/c1716bdc87e14ff78db57f835c508054
Autor:
Naresh Niranjan Dhanasekar, Soumeya Aliouane, Mathias Winterhalter, Jean-Marie Pagès, Jean-Michel Bolla
Publikováno v:
Biochemistry and Biophysics Reports, Vol 11, Iss C, Pp 79-83 (2017)
Here we report on translocation of short poly-arginines across the MOMP porin, the major outer membrane protein in the cell wall of Campylobacter jejuni. MOMP was purified to homogeneity from a pathogenic strain of C. jejuni. Its reconstitution in li
Externí odkaz:
https://doaj.org/article/fe7136f606a44a22926d059f34690804
Autor:
Suzanne Bialek-Davenet, Noémie Mayer, Julia Vergalli, Marion Duprilot, Sylvain Brisse, Jean-Marie Pagès, Marie-Hélène Nicolas-Chanoine
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Klebsiella pneumoniae, an Enterobacteriaceae that mostly causes hospital-acquired infections, belongs to the recently published WHO’s list of antibiotic-resistant pathogens that pose the greatest threat to human health. Indeed, K. pneumoni
Externí odkaz:
https://doaj.org/article/f6ea51cee31945f1be1b64b1c5abb1dd
Autor:
Anas Allam, Laure Maigre, Julia Vergalli, Estelle Dumont, Bertrand Cinquin, Rodolphe Alves de Sousa, Jelena Pajovic, Elizabeth Pinet, Nikaia Smith, Jean-Philippe Herbeuval, Matthieu Réfrégiers, Isabelle Artaud, Jean-Marie Pagès
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract A main challenge in chemotherapy is to determine the in cellulo parameters modulating the drug concentration required for therapeutic action. It is absolutely urgent to understand membrane permeation and intracellular concentration of antibi
Externí odkaz:
https://doaj.org/article/ca80691df79d435fac589a85f21b0920
Publikováno v:
Molecules, Vol 26, Iss 8, p 2374 (2021)
Multidrug resistance of bacteria is a worrying concern in the therapeutic field and an alternative method to combat it is designing new efflux pump inhibitors (EPIs). This article presents a molecular study of two quinazoline derivatives, labelled BG
Externí odkaz:
https://doaj.org/article/c5b1f79b3cc34f128309a8a4b175b87a
Publikováno v:
Microorganisms, Vol 8, Iss 6, p 833 (2020)
The transport of small molecules across membranes is a pivotal step for controlling the drug concentration into the bacterial cell and it efficiently contributes to the antibiotic susceptibility in Enterobacteriaceae. Two types of membrane transports
Externí odkaz:
https://doaj.org/article/ff228fb42d0644b89616d8af6ef9ff65
Publikováno v:
Antibiotics, Vol 9, Iss 6, p 323 (2020)
This study reported the phytochemical composition of two hydroethanolic extracts of Acacia senegal and Acacia seyal trees from Burkina Faso and their activities, alone or in combination with selected antibiotics, against multidrug resistant bacteria.
Externí odkaz:
https://doaj.org/article/49aa0e6625b348c4b94d58ad6c1d6bc5