Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Jean-Marie Leclerc"'
Autor:
Lynda M. Vrooman, Traci M. Blonquist, Marian H. Harris, Kristen E. Stevenson, Andrew E. Place, Sarah K. Hunt, Jane E. O'Brien, Barbara L. Asselin, Uma H. Athale, Luis A. Clavell, Peter D. Cole, Kara M. Kelly, Caroline Laverdiere, Jean-Marie Leclerc, Bruno Michon, Marshall A. Schorin, Maria Luisa Sulis, Jennifer J.G. Welch, Donna S. Neuberg, Stephen E. Sallan, Lewis B. Silverman
Publikováno v:
Blood Advances, Vol 2, Iss 12, Pp 1449-1458 (2018)
Abstract: Dana-Farber Cancer Institute (DFCI) ALL Consortium Protocol 05-001 tested a new risk stratification system in children and adolescents with newly diagnosed acute lymphoblastic leukemia (ALL). At study entry, B-ALL patients were classified a
Externí odkaz:
https://doaj.org/article/7fe5b025a97248a2bd7140b86b897665
Autor:
Thai Hoa Tran, Marian H. Harris, Jonathan V. Nguyen, Traci M. Blonquist, Kristen E. Stevenson, Eileen Stonerock, Barbara L. Asselin, Uma H. Athale, Luis A. Clavell, Peter D. Cole, Kara M. Kelly, Caroline Laverdiere, Jean-Marie Leclerc, Bruno Michon, Marshall A. Schorin, Jennifer J.G. Welch, Shalini C. Reshmi, Donna S. Neuberg, Stephen E. Sallan, Mignon L. Loh, Lewis B. Silverman
Publikováno v:
Blood Advances, Vol 2, Iss 5, Pp 529-533 (2018)
Abstract: Recurrent chromosomal rearrangements carry prognostic significance in pediatric B-lineage acute lymphoblastic leukemia (B-ALL). Recent genome-wide analyses identified a high-risk B-ALL subtype characterized by a diverse spectrum of genetic
Externí odkaz:
https://doaj.org/article/44b885b31a124a5584f54b008afc7fdf
Autor:
Francesco Ceppi, Michel Duval, Jean-Marie Leclerc, Caroline Laverdiere, Yves-Line Delva, Sonia Cellot, Pierre Teira, Henrique Bittencourt
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0160310 (2016)
Relapsed/refractory acute lymphoblastic leukemia (ALL) is a leading cause of death by cancer in children. Our institution has switched relapse treatment strategy to improve survival. We reviewed records of first relapse/refractory childhood ALL betwe
Externí odkaz:
https://doaj.org/article/3cb7a72190654a72805d30aef25df216
Autor:
Covida Mootoosamy, Maria Kondyli, Sophie Annaelle Serfaty, David-Étienne Tremblay, Vincent Gagné, Maïté Ribère, Caroline Laverdière, Jean-Marie Leclerc, Daniel Sinnett, Thai Hoa Tran, Maja Krajinovic
Publikováno v:
Pharmacogenomics. 24:199-206
Aim: We previously conducted exome-wide association study in acute lymphoblastic leukemia patients and identified association of five SNPs with asparaginase-related thrombosis. Here we aimed to replicate these findings in an independent patient cohor
Autor:
Jean-Marie Leclerc, Uma H. Athale, Emily Schultz, Lewis B. Silverman, Elena J. Ladas, Stephen E. Sallan, Marian H. Harris, Song Yao, Caroline Laverdière, Justine M. Kahn, Kristen E. Stevenson, Qianqian Zhu, Peter D. Cole, Kara M. Kelly, Marshall A. Schorin, Luis A. Clavell, Jennifer J.G. Welch, Bruno Michon
Publikováno v:
Blood Adv
Hispanic children have a higher incidence of acute lymphoblastic leukemia (ALL) and inferior treatment outcomes relative to non-Hispanic White children. We previously reported that Hispanic children with ALL had lower risk of fracture and osteonecros
Autor:
Uma H. Athale, Stephen E. Sallan, Maneka Puligandla, Luis A. Clavell, Lewis B. Silverman, Elena J. Ladas, Kara M. Kelly, Manuela Orjuela, Caroline Laverdière, Jennifer J.G. Welch, Barbara L. Asselin, Kristen E. Stevenson, Bruno Michon, Traci M. Blonquist, Marshall A. Schorin, Jean-Marie Leclerc, Peter D. Cole
Publikováno v:
Journal of Clinical Oncology. 38:2151-2159
PURPOSE The benefits and risks of supplementation with antioxidants during cancer therapy have been a controversial area. Few studies have systematically evaluated dietary intake of antioxidants with toxicity and survival in childhood cancer. We soug
Autor:
Uma H. Athale, Yael Flamand, Traci Blonquist, Kristen E. Stevenson, Menachem Spira, Barbara L. Asselin, Luis A. Clavell, Peter D. Cole, Kara M. Kelly, Caroline Laverdiere, Jean‐Marie Leclerc, Bruno Michon, Marshall A. Schorin, Jennifer J.G. Welch, Marian H. Harris, Donna S. Neuberg, Stephen E. Sallan, Lewis B. Silverman
Publikováno v:
Pediatric bloodcancerREFERENCES. 69(8)
Although thromboembolism (TE) is a serious complication in patients with acute lymphoblastic leukemia (ALL), thromboprophylaxis is not commonly used due to the inherent bleeding risk in this population. Identifying prothrombotic risk factors will hel
Autor:
Jennifer J.G. Welch, Luis A. Clavell, Sarah K. Hunt, Sarah M. Cronholm, Peter D. Cole, Kristen E. Stevenson, Jeffrey G. Supko, Bruno Michon, Donna Neuberg, Samantha Kay-Green, Kara M. Kelly, Jean-Marie Leclerc, Lynda M. Vrooman, Caroline Laverdière, Uma H. Athale, Traci M. Blonquist, Stephen E. Sallan, Marian H. Harris, Lewis B. Silverman, Victoria Koch, Andrew E. Place, Marshall A. Schorin
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 39(31)
PURPOSE Dana-Farber Cancer Institute Acute Lymphoblastic Leukemia (ALL) Consortium Protocol 11-001 assessed efficacy and toxicity of calaspargase pegol (calaspargase), a novel pegylated asparaginase formulation with longer half-life, compared with th
Autor:
Thai Hoa Tran, Sylvie Langlois, Caroline Meloche, Maxime Caron, Pascal Saint-Onge, Alexandre Rouette, Alain R. Bataille, Camille Jimenez-Cortes, Thomas Sontag, Henrique Bittencourt, Caroline Laverdière, Vincent-Philippe Lavallée, Jean-Marie Leclerc, Peter D. Cole, Lisa M. Gennarini, Justine M. Kahn, Kara M. Kelly, Bruno Michon, Raoul Santiago, Kristen E. Stevenson, Jennifer J. G. Welch, Kaitlin M. Schroeder, Victoria Koch, Sonia Cellot, Lewis B. Silverman, Daniel Sinnett
Publikováno v:
Blood advances. 6(4)
The molecular hallmark of childhood acute lymphoblastic leukemia (ALL) is characterized by recurrent, prognostic genetic alterations, many of which are cryptic by conventional cytogenetics. RNA sequencing (RNA-seq) is a powerful next-generation seque
Autor:
Vincent Gagné, Jean-Marie Leclerc, Rachid Abaji, Maria Plesa, Lewis B. Silverman, Nathalie Alos, Donna Neuberg, Pascal St-Onge, Patrick Beaulieu, Jeffery L. Kutok, Caroline Laverdière, Kateryna Petrykey, Anne Aubry-Morin, Stephen E. Sallan, Daniel Sinnett, Maja Krajinovic
Publikováno v:
Pharmacogenomics
Aim: To evaluate top-ranking genes identified through genome-wide association studies for an association with corticosteroid-related osteonecrosis in children with acute lymphoblastic leukemia (ALL) who received Dana–Farber Cancer Institute treatme