Zobrazeno 1 - 10
of 419
pro vyhledávání: '"Jean-Marie Launay"'
Autor:
Jean-Marie Launay, Richard Delorme, Cécile Pagan, Jacques Callebert, Marion Leboyer, Nicolas Vodovar
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Hyperserotonemia is the most replicated biochemical anomaly associated with autism spectrum disorder (ASD) and has been reported in 35–46% of individuals with ASD. Serotonin is synthesised from the essential amino acid tryptophan (TRP). Ho
Externí odkaz:
https://doaj.org/article/65dc33d638864954abaaef6346488306
Autor:
Alejandro Orrico-Sanchez, Bruno P. Guiard, Stella Manta, Jacques Callebert, Jean-Marie Launay, Franck Louis, Antoine Paccard, Carole Gruszczynski, Catalina Betancur, Vincent Vialou, Sophie Gautron
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Selective serotonin reuptake inhibitors (SSRI) are common first-line treatments for major depression. However, a significant number of depressed patients do not respond adequately to these pharmacological treatments. In the present preclinic
Externí odkaz:
https://doaj.org/article/d94a2324bd604020be6ec223f77ddc2a
Autor:
Hélène Nougué, François Picard, Alain Cohen-Solal, Damien Logeart, Jean-Marie Launay, Nicolas Vodovar
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108520- (2024)
Summary: In heart failure patients with reduced ejection fraction, Sacubitril/valsartan (S/V) increased proBNP T71 glycosylation, which is regulated negatively by hypoxia via miR-30a in vitro. Using a cohort of 73 HFrEF patients who were transitioned
Externí odkaz:
https://doaj.org/article/dffa87be72a84566b41822bc6def582c
Autor:
Juliette Canaguier, Jean-Marie Launay, Jacques Callebert, Nicolas Glaichenhaus, Laetitia Davidovic
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S81- (2023)
Externí odkaz:
https://doaj.org/article/733e9d8b5e5348719ab3ec77e83b246c
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S765- (2023)
Externí odkaz:
https://doaj.org/article/366ddc4794b445b2b422247be4a03342
Autor:
Olivier Schussler, Luc Maroteaux, Ramadan Jashari, Pierre Falcoz, Marco Alifano, Yves Lecarpentier, Jean-Marie Launay
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
ObjectivesAlthough critical in animal and human development and pathology, a measurement of the quantitative expression of 5-HTR serotonin receptors on animal or human valvular tissues has never been performed.MethodsQuantification of the most freque
Externí odkaz:
https://doaj.org/article/0bb0bc890b344042b7fd358211a161ae
Autor:
Patricia Bermudez-Martin, Jérôme A. J. Becker, Nicolas Caramello, Sebastian P. Fernandez, Renan Costa-Campos, Juliette Canaguier, Susana Barbosa, Laura Martinez-Gili, Antonis Myridakis, Marc-Emmanuel Dumas, Aurélia Bruneau, Claire Cherbuy, Philippe Langella, Jacques Callebert, Jean-Marie Launay, Joëlle Chabry, Jacques Barik, Julie Le Merrer, Nicolas Glaichenhaus, Laetitia Davidovic
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-23 (2021)
Abstract Background Autism spectrum disorders (ASD) are associated with dysregulation of the microbiota-gut-brain axis, changes in microbiota composition as well as in the fecal, serum, and urine levels of microbial metabolites. Yet a causal relation
Externí odkaz:
https://doaj.org/article/528d90be0f624b76bc049fae162ed6dc
Autor:
Antoine deZélicourt, Abdallah Fayssoil, Mbarka Dakouane‐Giudicelli, Isley De Jesus, Ahmed Karoui, Faouzi Zarrouki, Florence Lefebvre, Arnaud Mansart, Jean‐Marie Launay, Jerome Piquereau, Mariana G Tarragó, Marcel Bonay, Anne Forand, Sophie Moog, France Piétri‐Rouxel, Elise Brisebard, Claudia C S Chini, Sonu Kashyap, Matthew J Fogarty, Gary C Sieck, Mathias Mericskay, Eduardo N Chini, Ana Maria Gomez, José‐Manuel Cancela, Sabine de laPorte
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 5, Pp n/a-n/a (2022)
Abstract Duchenne muscular dystrophy (DMD) is characterized by progressive muscle degeneration. Two important deleterious features are a Ca2+ dysregulation linked to Ca2+ influxes associated with ryanodine receptor hyperactivation, and a muscular nic
Externí odkaz:
https://doaj.org/article/ff8aa5831114408f802cc62d7a45fce4
Autor:
Adrien Cogo, Gabrielle Mangin, Benjamin Maïer, Jacques Callebert, Mikael Mazighi, Hughes Chabriat, Jean-Marie Launay, Gilles Huberfeld, Nathalie Kubis
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-20 (2021)
Abstract Background Strokes are becoming less severe due to increased numbers of intensive care units and improved treatments. As patients survive longer, post-stroke cognitive impairment (PSCI) has become a major health public issue. Diabetes has be
Externí odkaz:
https://doaj.org/article/62e83ba1ac804a83b1a90f59e0943056
Autor:
Cécile Pagan, Marion Benabou, Claire Leblond, Freddy Cliquet, Alexandre Mathieu, Nathalie Lemière, Hany Goubran-Botros, Richard Delorme, Marion Leboyer, Jacques Callebert, Thomas Bourgeron, Jean-Marie Launay
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Hyperserotonemia is the most replicated biochemical abnormality associated with autism spectrum disorders (ASD). However, previous studies of serotonin synthesis, catabolism, and transport have not elucidated the mechanisms underlying this h
Externí odkaz:
https://doaj.org/article/b4b9eb21b06748ebbc6ea0d7aceced5f