Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Jean-Marie Guigonis"'
Autor:
Caroline Bailleux, David Chardin, Jean-Marie Guigonis, Jean-Marc Ferrero, Yann Chateau, Olivier Humbert, Thierry Pourcher, Jocelyn Gal
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 5136-5143 (2023)
Purpose: Meta-analyses failed to accurately identify patients with non-metastatic breast cancer who are likely to benefit from chemotherapy, and metabolomics could provide new answers. In our previous published work, patients were clustered using fiv
Externí odkaz:
https://doaj.org/article/816f939c016a42129efa98d1890845fc
Autor:
David Chardin, Lun Jing, Mélanie Chazal-Ngo-Mai, Jean-Marie Guigonis, Valérie Rigau, Catherine Goze, Hugues Duffau, Thierry Virolle, Thierry Pourcher, Fanny Burel-Vandenbos
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16697 (2023)
The aim of this study was to identify metabolomic signatures associated with the gliomagenesis pathway (IDH-mutant or IDH-wt) and tumor grade of diffuse gliomas (DGs) according to the 2021 WHO classification on frozen samples and to evaluate the diag
Externí odkaz:
https://doaj.org/article/de65fddd05164d3996b7354efd2c86c3
Autor:
Céline Occelli, Jean-Marie Guigonis, Sabine Lindenthal, Alexandre Cagnard, Fanny Graslin, Vesna Brglez, Barbara Seitz-Polski, Jean Dellamonica, Jacques Levraut, Thierry Pourcher
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
ObjectivesThe COVID-19 pandemic has been a serious worldwide public health crisis since 2020 and is still challenging healthcare systems. New tools for the prognosis and diagnosis of COVID-19 patients remain important issues.DesignHere, we studied th
Externí odkaz:
https://doaj.org/article/8fcdc1b199e84be1a28a3f8d443dc0a6
Autor:
Grégoire D’Andréa, Lun Jing, Isabelle Peyrottes, Jean-Marie Guigonis, Fanny Graslin, Sabine Lindenthal, Julie Sanglier, Isabel Gimenez, Juliette Haudebourg, Clair Vandersteen, Alexandre Bozec, Nicolas Guevara, Thierry Pourcher
Publikováno v:
Metabolites, Vol 13, Iss 7, p 782 (2023)
Although it is the gold standard for assessing the malignancy of thyroid nodules (TNs) preoperatively, the cytological analysis of fine-needle aspiration cytology (FNAC) samples results in 20–30% of cases in indeterminate lesions (ITNs). As two-thi
Externí odkaz:
https://doaj.org/article/e61f5079deeb4065bc5141b86c53c349
Autor:
Caroline Bailleux, David Chardin, Jocelyn Gal, Jean-Marie Guigonis, Sabine Lindenthal, Fanny Graslin, Laurent Arnould, Alexandre Cagnard, Jean-Marc Ferrero, Olivier Humbert, Thierry Pourcher
Publikováno v:
Cancers, Vol 15, Iss 7, p 1941 (2023)
Purpose: Identification of metabolomic biomarkers of high SBR grade in non-metastatic breast cancer. Methods: This retrospective bicentric metabolomic analysis included a training set (n = 51) and a validation set (n = 49) of breast cancer tumors, al
Externí odkaz:
https://doaj.org/article/01018418909b43e8894f773e435e205d
Autor:
Jocelyn Gal, Caroline Bailleux, David Chardin, Thierry Pourcher, Julia Gilhodes, Lun Jing, Jean-Marie Guigonis, Jean-Marc Ferrero, Gerard Milano, Baharia Mograbi, Patrick Brest, Yann Chateau, Olivier Humbert, Emmanuel Chamorey
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 1509-1524 (2020)
Genomics and transcriptomics have led to the widely-used molecular classification of breast cancer (BC). However, heterogeneous biological behaviors persist within breast cancer subtypes. Metabolomics is a rapidly-expanding field of study dedicated t
Externí odkaz:
https://doaj.org/article/1231c5e493db4c508ef5a525afd36765
Autor:
Fabio Castillo-Rivera, Alejandro Ondo-Méndez, Julien Guglielmi, Jean-Marie Guigonis, Lun Jing, Sabine Lindenthal, Andrea Gonzalez, Diana López, Béatrice Cambien, Thierry Pourcher
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100937- (2021)
For decades, sodium/iodide symporter NIS-mediated iodide uptake has played a crucial role in the radioactive ablation of thyroid cancer cells. NIS-based gene therapy has also become a promising tool for the treatment of tumors of extrathyroidal origi
Externí odkaz:
https://doaj.org/article/d5baa942ad04456ab8599c560d83ff6e
Autor:
Sonia Maatoug, Amani Cheikh, Oussema Khamessi, Hager Tabka, Zied Landoulsi, Jean-Marie Guigonis, Sylvie Diochot, Saïd Bendahhou, Rym Benkhalifa
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12290 (2021)
The voltage-gated K+ channels Kv3.1 display fast activation and deactivation kinetics and are known to have a crucial contribution to the fast-spiking phenotype of certain neurons. AahG50, as a natural product extracted from Androctonus australis hec
Externí odkaz:
https://doaj.org/article/f1589d1d72c34914a1494d435f104141
Autor:
Abderrahman Chargui, Amine Belaid, Papa Diogop Ndiaye, Véronique Imbert, Michel Samson, Jean-Marie Guigonis, Michel Tauc, Jean-François Peyron, Philippe Poujeol, Patrick Brest, Paul Hofman, Baharia Mograbi
Publikováno v:
Cancers, Vol 13, Iss 10, p 2490 (2021)
Signaling, proliferation, and inflammation are dependent on K63-linked ubiquitination—conjugation of a chain of ubiquitin molecules linked via lysine 63. However, very little information is currently available about how K63-linked ubiquitination is
Externí odkaz:
https://doaj.org/article/41013859a18e4463b3d04b0b658ab504
Autor:
Laurent Suissa, Pavel Kotchetkov, Jean-Marie Guigonis, Emilie Doche, Ophélie Osman, Thierry Pourcher, Sabine Lindenthal
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 524 (2021)
The role of ketone bodies in the cerebral energy homeostasis of neurological diseases has begun to attract recent attention particularly in acute neurological diseases. In ketogenic therapies, ketosis is achieved by either a ketogenic diet or by the
Externí odkaz:
https://doaj.org/article/ed9e96a747f44db19bf97d89b8cb09b7