The WHHERE coactivator complex is required for retinoic acid-dependent regulation of embryonic symmetry

Autor: Gonçalo C. Vilhais-Neto, Marjorie Fournier, Jean-Luc Plassat, Mihaela E. Sardiu, Anita Saraf, Jean-Marie Garnier, Mitsuji Maruhashi, Laurence Florens, Michael P. Washburn, Olivier Pourquié

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)

Retinoic acid (RA) regulates the maintenance of somitogenesis symmetry. Here, the authors use a proteomic approach to identify a protein complex of Wdr5, Hdac1, Hdac2 that act together with RA and coactivator Rere/Atrophin2 and a histone methyltransf

Externí odkaz: https://doaj.org/article/c0924751d1f6443c91a937ddd9181ef0

TAF8 regions important for TFIID lobe B assembly or for TAF2 interactions are required for embryonic stem cell survival

Autor: Laszlo Tora, Elisabeth Scheer, Jean-Marie Garnier, Frank Ruffenach, Imre Berger, Jie Luo, Jeff Ranish, Andrea Bernardini, Kapil Gupta, Isabelle Kolb-Cheynel

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2021, 297, ⟨10.1016/j.jbc.2021.101288⟩
The Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2021, pp.101288. ⟨10.1016/j.jbc.2021.101288⟩
Journal of Biological Chemistry, 2021, 297, ⟨10.1016/j.jbc.2021.101288⟩
Scheer, E, Luo, J, Bernardini, A, Ruffenach, F, Garnier, J-M, Kolb-Cheynel, I, Gupta, K, Berger, I, Ranish, J & Tora, L 2021, ' TAF8 regions important for TFIID lobe B assembly or for TAF2 interactions are required for embryonic stem cell survival ', Journal of Biological Chemistry, vol. 297, no. 5, 101288 . https://doi.org/10.1016/j.jbc.2021.101288

International audience; The human general transcription factor TFIID is composed of the TATA-binding protein (TBP) and 13 TBP-associated factors (TAFs). In eukaryotic cells, TFIID is thought to nucleate RNA polymerase II (Pol II) preinitiation comple

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::995cfc0af4001245182a9892156c74bb
https://hal.archives-ouvertes.fr/hal-03409582

Differentiation of the human PAX7-positive myogenic precursors/satellite cell lineage in vitro

Autor: Arielle Hall, Olivier Tassy, Emanuela Gussoni, Jyoti Rao, Svetlana Gapon, Aurore Hick, Olivier Pourquié, Erica Wagner, Ziad Al Tanoury, Bénédicte Gobert, Jean-Marie Garnier

Publikováno v: Development
Development, 2020, 147 (12), ⟨10.1242/dev.187344⟩

Satellite cells (SC) are muscle stem cells which can regenerate adult muscles upon injury. Most SC originate from PAX7-positive myogenic precursors set aside during development. While myogenesis has been studied in mouse and chicken embryos, little i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9c8370b2144bdd931e0927994651b7d
https://doi.org/10.1242/dev.187344

A no-stop mutation in MAGEB4 is a possible cause of rare X-linked azoospermia and oligozoospermia in a consanguineous Turkish family

Autor: Moncef Benkhalifa, Stéphane Viville, Sabine Kliesch, Nicolas Charlet-Berguerand, Munevver Serdarogullari, Angeline Gaucherot, Isabelle Aknin, Ozlem Okutman, Frank Tüttelmann, Viviana Herbepin, Mustafa Bahceci, Meral Gultomruk, Ellen Goossens, Jean Marie Garnier, Valérie Lamour, Yoni Baert, Jean Muller, Emre Bakircioglu, Valerie Skory, Marius Teletin, Albrecht Röpke

Publikováno v: Journal of Assisted Reproduction and Genetics
Journal of Assisted Reproduction and Genetics, Springer Verlag, 2017, 34 (5), pp.683-694. ⟨10.1007/s10815-017-0900-z⟩
Journal of Assisted Reproduction and Genetics, 2017, 34 (5), pp.683-694. ⟨10.1007/s10815-017-0900-z⟩

PURPOSE: The purpose of this study was to identify mutations that cause non-syndromic male infertility using whole exome sequencing of family cases. METHODS: We recruited a consanguineous Turkish family comprising nine siblings with male triplets; tw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52fa96f08dd57f5a681ab1fecadd8899
https://doi.org/10.1007/s10815-017-0900-z

Co-translational assembly of mammalian nuclear multisubunit complexes

Autor: Sascha Conic, Paul Bardot, Simona Capponi, Florian Mueller, Jean-Marie Garnier, Pooja Mukherjee, Doulaye Dembélé, Ivanka Kamenova, Farrah El-Saafin, Laszlo Tora, H. T. Marc Timmers, Stéphane D. Vincent

Publikováno v: Nature Communications
Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-09749-y⟩
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-09749-y⟩
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)

Cells dedicate significant energy to build proteins often organized in multiprotein assemblies with tightly regulated stoichiometries. As genes encoding subunits assembling in a multisubunit complex are dispersed in the genome of eukaryotes, it is un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef7ce86e83a73a7b0b8df132833c32f
https://hal.science/hal-02130219/document