Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jean-Marie Delbos"'
Autor:
Jean-Marie Delbos, Esther Steidl, Tuulia Huhtala, Aurore Sors, Jean-Michel Arrang, Bruno Buisson, Patrick Casara, Outi Kontkanen, Lionel Bert, Valérie Audinot, Pierre Lestage, Olivier Nosjean, Anne-Marie Chollet, Fany Panayi, Dominique Favale
Publikováno v:
European Journal of Pharmacology. 803:11-23
Histaminergic H3 inverse agonists, by stimulating central histamine release, represent attractive drug candidates to treat cognitive disorders. The present studies aimed to describe the mechanistic profile of S 38093 a novel H3 receptors inverse agon
Autor:
Caroline Chemin, Jean-Manuel Péan, Thomas Arnauld, Xavier Declèves, Betty Gourdon, Amélie Moreau, Jean-Marie Delbos
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 129
Oral administration of peptides still remains a challenging issue. We previously pointed out the possibility to target intestinal PepT1 transporter with functionalized PLA-PEG nanoparticles (NPs) formulated by nanoprecipitation, and to improve drug-l
Autor:
Anjali Seth, Jean-Manuel Péan, Alain Laporte, Jean-Marie Delbos, Cécile Poirier, Christine Ménager, Thomas Badier, David Lafargue, Véronique Jeannin, Nathalie Delory
Publikováno v:
European Journal of Pharmaceutical Sciences
European Journal of Pharmaceutical Sciences, 2016, ⟨10.1016/j.ejps.2016.12.022⟩
European Journal of Pharmaceutical Sciences, Elsevier, 2016, ⟨10.1016/j.ejps.2016.12.022⟩
European Journal of Pharmaceutical Sciences, 2016, ⟨10.1016/j.ejps.2016.12.022⟩
European Journal of Pharmaceutical Sciences, Elsevier, 2016, ⟨10.1016/j.ejps.2016.12.022⟩
International audience; Oral administration of low permeable drugs remains a challenge as they do not cross biological membrane efficiently and therefore exhibit a poor bioavailability. Herein, the effect of magnetic retention on the circulation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2116892e5a815aab40108c21089a1641
https://hal.sorbonne-universite.fr/hal-01427399
https://hal.sorbonne-universite.fr/hal-01427399
Autor:
Jonathan Stauber, Fabien Pamelard, Jean-Marie Delbos, Gregory Hamm, François Bouzom, Raphael Legouffe, David Bonnel
Publikováno v:
Journal of Proteomics. 75:4952-4961
In order to quantify small molecules at the early stage of drug discovery, we developed a quantitation approach based on mass spectrometry imaging (MSI) using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS)
Autor:
Bernard Testa, Joachim M. Mayer, Marianne Reist, Jean-Marie Delbos, Pierre-Alain Carrupt, Marc-Etienne Castella, Bernard Walther, Claire Boursier-Neyret, Jean-Jacques Turban
Publikováno v:
Pharmaceutical Research, Vol. 23, No 7 (2006) pp. 1543-1553
PURPOSE: The aims of the study are to develop and evaluate an in vitro rat intestine segmental perfusion model for the prediction of the oral fraction absorbed of compounds and to assess the ability of the model to study intestinal metabolism. METHOD
Autor:
Olivier Lacombe, John F. Woodley, Georges Houin, Claire Boursier-Neyret, Claude Solleux, Jean-Marie Delbos
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 23(4-5)
The small intestine is the major site of drug absorption. Some reports in the literature have evoked the concept of “absorption windows” in the small intestine: are there specific regions where drug absorption is significantly higher than others?
Autor:
Géraldine Carrot, Jean-Marie Delbos, Francois Lefoulon, Thomas Arnauld, Olivier Loreau, Eric Doris, Julien Ogier, Claire Boursier, Antoine Lhumeau
Publikováno v:
Organic & Biomolecular Chemistry. 8:3902
A new drug carrier system based on self-assembly and polymerization of polydiacetylenic amphiphiles is described. Although classical amphiphiles can help in solubilizing hydrophobic molecules upon self-arrangement into a variety of nanometric structu
Autor:
Alain Le Pape, Jean-Manuel Pean, Michèle German-Fattal, Caroline Chemin, Jean-Marie Delbos, Patrick Couvreur, Patrick Wüthrich
Publikováno v:
Journal of Liposome Research. :090730043007050-11
S12363 is a potent therapeutic agent with a strong in vitro activity against a variety of tumor types but also a high in vivo toxicity. Loading of this drug into long-circulating liposomes is expected to enhance its therapeutic index. Pharmacokinetic