Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jean-Marc Kühnel"'
Publikováno v:
Journal of Cellular Physiology. 184:364-372
Folate compound transport into Fisher rat 3T3 (FR3T3) cells at physiological pH occurs predominantly by an acid pH-dependent, mobile carrier system. However, influx of [3H]MTX by this system is 3–4-fold higher at pH 6 than at pH 7.5, the optimum fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd0f5f9b841ce209e865fd584f048fd7
https://doi.org/10.1002/1097-4652(200009)184:3<364::aid-jcp11>3.0.co
https://doi.org/10.1002/1097-4652(200009)184:3<364::aid-jcp11>3.0.co
Autor:
Yves Rolland, Marc A. Schwaller, Genevieve Chapuis, Guy Lewin, Jean-Marc Kühnel, Jacques Ferte
Publikováno v:
Journal of Medicinal Chemistry. 42:478-489
A series of 28 flavonoid derivatives containing a N-benzylpiperazine chain have been synthesized and tested for their ability to modulate multidrug resistance (MDR) in vitro. At 5 microM, most compounds potentiated doxorubicin cytotoxicity on resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fbfe4111a5a025944373a1eb25fa3ef
https://doi.org/10.1021/jm981064b
https://doi.org/10.1021/jm981064b
Publikováno v:
Biochemical and biophysical research communications. 186(3)
Summary Bis-pyridium oximes and methoximes from a newly synthesized series are weak DNA binders (K= 3.104 M−1 under physiological conditions). From the number of binding sites per phosphate, 0.25, the ionic strength dependence of the binding consta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0faadc0a02a0ddba3babad79c77a9acb
https://pubmed.ncbi.nlm.nih.gov/1510682
https://pubmed.ncbi.nlm.nih.gov/1510682