Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jean-Marc Girodeau"'
Autor:
R. M. Mcmillan, Pierre Andre Raymond Bruneau, John F. Kingston, T. Geoffrey C. Bird, Graham Charles Crawley, Martin Paul Edwards, Jean Marc Girodeau, S. J. Foster
Publikováno v:
Journal of medicinal chemistry. 34(7)
(Methoxyalkyl)thiazoles are novel 5-lipoxygenase (5-LPO) inhibitors that are neither redox agents nor iron chelators. Consideration of a hypothetical model of the enzyme active site led to this series which is exemplified by 1-[3-(naphth-2-ylmethoxy)
Publikováno v:
Helvetica Chimica Acta. 63:2096-2111
A number of functionalized and chiral macrocyclic polyethers have been synthesized by condensation of the dithallium alcoholate of (R,R)-(+)-tartaric acid derivatives with α, ω-dihalides. In this way for instance, the tetracarboxylic [18]-O6 macroc
Publikováno v:
Chemischer Informationsdienst. 17
Publikováno v:
The Journal of antibiotics. 37(2)
Lividamine and paromamine were converted into two key intermediate ethylenic aldehydes 10a and 10b. Reductive amination of the two aldehydes yielded the protected sisamine 11a and the three analogs 11b, 12a and 12b. These four derivatives were deprot
Publikováno v:
Chemischer Informationsdienst. 12
Das Di-Tl-Salz (Ib) des (R,R)-Weinsaurediamids (Ia) reagiert mit dem Diiodid (II) unter Bildung des makrocyclischen Polyethers (IIIa) (daneben wenig des Trimeren (IV)); analog wird aus dem Bisamid (Ic) uber (Id) mit (II) das Analoge (IIIb) erhalten.
Publikováno v:
Chemischer Informationsdienst. 7
Publikováno v:
Angewandte Chemie. 87:813-814
Publikováno v:
Angewandte Chemie International Edition in English. 14:764-764