Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Jean-Marc Daran"'
Autor:
Else-Jasmijn Hassing, Joran Buijs, Nikki Blankerts, Marijke A. Luttik, Erik A.de Hulster, Jack T. Pronk, Jean-Marc Daran
Publikováno v:
Metabolic Engineering Communications, Vol 13, Iss , Pp e00183- (2021)
Engineered strains of the yeast Saccharomyces cerevisiae are intensively studied as production platforms for aromatic compounds such as hydroxycinnamic acids, stilbenoids and flavonoids. Heterologous pathways for production of these compounds use l-p
Externí odkaz:
https://doaj.org/article/c9a2e59fa0a44416b4ecc36d4cd04d4a
Autor:
Thomas Perli, Aurin M. Vos, Jonna Bouwknegt, Wijb J. C. Dekker, Sanne J. Wiersma, Christiaan Mooiman, Raúl A. Ortiz-Merino, Jean-Marc Daran, Jack T. Pronk
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
NAD (NAD +
Externí odkaz:
https://doaj.org/article/2c7a24206abd492c8d61605236a867e5
Autor:
Mark Levisson, Constantinos Patinios, Sascha Hein, Philip A. de Groot, Jean-Marc Daran, Robert D. Hall, Stefan Martens, Jules Beekwilder
Publikováno v:
Microbial Cell Factories, Vol 17, Iss 1, Pp 1-16 (2018)
Abstract Background Anthocyanins are polyphenolic pigments which provide pink to blue colours in fruits and flowers. There is an increasing demand for anthocyanins, as food colorants and as health-promoting substances. Plant production of anthocyanin
Externí odkaz:
https://doaj.org/article/915e3fb1d6ae4254a995c1d7a9a43c26
Autor:
Francine J. Boonekamp, Sofia Dashko, Marcel van den Broek, Thies Gehrmann, Jean-Marc Daran, Pascale Daran-Lapujade
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
The ability of the yeast Saccharomyces cerevisiae to convert glucose, even in the presence of oxygen, via glycolysis and the fermentative pathway to ethanol has played an important role in its domestication. Despite the extensive knowledge on these p
Externí odkaz:
https://doaj.org/article/b2fb9ac02a314ee393c3a761b83153b8
Autor:
Barbara U. Kozak, Harmen M. van Rossum, Marijke A. H. Luttik, Michiel Akeroyd, Kirsten R. Benjamin, Liang Wu, Simon de Vries, Jean-Marc Daran, Jack T. Pronk, Antonius J. A. van Maris
Publikováno v:
mBio, Vol 5, Iss 5 (2014)
ABSTRACT The energetic (ATP) cost of biochemical pathways critically determines the maximum yield of metabolites of vital or commercial relevance. Cytosolic acetyl coenzyme A (acetyl-CoA) is a key precursor for biosynthesis in eukaryotes and for many
Externí odkaz:
https://doaj.org/article/946bda757b034a43b8cc702e6477923b
Autor:
Helén Olsson, Paul Cachera, Hilde Coumou, Mads L. Jensen, Benjamín J. Sánchez, Tomas Strucko, Marcel van den Broek, Jean-Marc Daran, Michael K. Jensen, Nikolaus Sonnenschein, Michael Lisby, Uffe H. Mortensen
Biological functions are orchestrated by intricate networks of interacting genetic elements. Predicting the interaction landscape remains a challenge for systems biology and the identification of phenotypic maximas would be of great benefit to synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::993ef7c9b9d3674f40a99fd4cf6d6ef9
https://doi.org/10.1101/2022.07.19.500587
https://doi.org/10.1101/2022.07.19.500587
Autor:
Francine J. Boonekamp, Ewout Knibbe, Marcel A. Vieira-Lara, Melanie Wijsman, Marijke A.H. Luttik, Karen van Eunen, Maxime den Ridder, Reinier Bron, Ana Maria Almonacid Suarez, Patrick van Rijn, Justina C. Wolters, Martin Pabst, Jean-Marc Daran, Barbara M. Bakker, Pascale Daran-Lapujade
Publikováno v:
Cell Reports, 39(13):111010. Cell Press
Cell reports, 39(13):111010. CELL PRESS
Cell Reports, 39(13)
Cell reports, 39(13):111010. CELL PRESS
Cell Reports, 39(13)
Although transplantation of single genes in yeast plays a key role in elucidating gene functionality in metazoans, technical challenges hamper humanization of full pathways and processes. Empowered by advances in synthetic biology, this study demonst
A supernumerary designer chromosome for modular in vivo pathway assembly in Saccharomyces cerevisiae
Autor:
Pascale Daran-Lapujade, Sofia Dashko, Jean-Marc Daran, Marcel van den Broek, Eline D. Postma, Shannara K. Taylor Parkins, Lars van Breemen
Publikováno v:
Nucleic Acids Research
Nucleic acids research, 49(3)
Nucleic acids research, 49(3)
The construction of microbial cell factories for sustainable production of chemicals and pharmaceuticals requires extensive genome engineering. UsingSaccharomyces cerevisiae, this study proposes Synthetic Chromosomes (SynChs) as orthogonal expression
Publikováno v:
Metabolic Engineering
Metabolic Engineering, 56
Metabolic Engineering, 56
The organic compound 2-phenylethanol (2PE) has a pleasant floral scent and is intensively used in the cosmetic and food industries. Microbial production of 2PE by phenylalanine bioconversion orde novobiosynthesis from sugar offer sustainable, reliabl
Genetic bases for the metabolism of the DMS precursor S-methylmethionine by Saccharomyces cerevisiae
Autor:
Matthias Eder, Isabelle Sanchez, Carole Camarasa, Jean-Marc Daran, Jean-Luc Legras, Sylvie Dequin
Publikováno v:
Food microbiology. 106
Dimethyl sulfide (DMS) is a sulfur containing volatile that enhances general fruity aroma and imparts aromatic notes in wine. The most important precursor of DMS is S-methylmethionine (SMM), which is synthesized by grapes and can be metabolized by th