Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Jean-Marc Daran"'
Autor:
Else-Jasmijn Hassing, Joran Buijs, Nikki Blankerts, Marijke A. Luttik, Erik A.de Hulster, Jack T. Pronk, Jean-Marc Daran
Publikováno v:
Metabolic Engineering Communications, Vol 13, Iss , Pp e00183- (2021)
Engineered strains of the yeast Saccharomyces cerevisiae are intensively studied as production platforms for aromatic compounds such as hydroxycinnamic acids, stilbenoids and flavonoids. Heterologous pathways for production of these compounds use l-p
Externí odkaz:
https://doaj.org/article/c9a2e59fa0a44416b4ecc36d4cd04d4a
Autor:
Thomas Perli, Aurin M. Vos, Jonna Bouwknegt, Wijb J. C. Dekker, Sanne J. Wiersma, Christiaan Mooiman, Raúl A. Ortiz-Merino, Jean-Marc Daran, Jack T. Pronk
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
NAD (NAD +
Externí odkaz:
https://doaj.org/article/2c7a24206abd492c8d61605236a867e5
Autor:
Mark Levisson, Constantinos Patinios, Sascha Hein, Philip A. de Groot, Jean-Marc Daran, Robert D. Hall, Stefan Martens, Jules Beekwilder
Publikováno v:
Microbial Cell Factories, Vol 17, Iss 1, Pp 1-16 (2018)
Abstract Background Anthocyanins are polyphenolic pigments which provide pink to blue colours in fruits and flowers. There is an increasing demand for anthocyanins, as food colorants and as health-promoting substances. Plant production of anthocyanin
Externí odkaz:
https://doaj.org/article/915e3fb1d6ae4254a995c1d7a9a43c26
Autor:
Francine J. Boonekamp, Sofia Dashko, Marcel van den Broek, Thies Gehrmann, Jean-Marc Daran, Pascale Daran-Lapujade
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
The ability of the yeast Saccharomyces cerevisiae to convert glucose, even in the presence of oxygen, via glycolysis and the fermentative pathway to ethanol has played an important role in its domestication. Despite the extensive knowledge on these p
Externí odkaz:
https://doaj.org/article/b2fb9ac02a314ee393c3a761b83153b8
Autor:
Helén Olsson, Paul Cachera, Hilde Coumou, Mads L. Jensen, Benjamín J. Sánchez, Tomas Strucko, Marcel van den Broek, Jean-Marc Daran, Michael K. Jensen, Nikolaus Sonnenschein, Michael Lisby, Uffe H. Mortensen
Biological functions are orchestrated by intricate networks of interacting genetic elements. Predicting the interaction landscape remains a challenge for systems biology and the identification of phenotypic maximas would be of great benefit to synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::993ef7c9b9d3674f40a99fd4cf6d6ef9
https://doi.org/10.1101/2022.07.19.500587
https://doi.org/10.1101/2022.07.19.500587
Autor:
Francine J. Boonekamp, Ewout Knibbe, Marcel A. Vieira-Lara, Melanie Wijsman, Marijke A.H. Luttik, Karen van Eunen, Maxime den Ridder, Reinier Bron, Ana Maria Almonacid Suarez, Patrick van Rijn, Justina C. Wolters, Martin Pabst, Jean-Marc Daran, Barbara M. Bakker, Pascale Daran-Lapujade
Publikováno v:
Cell Reports, 39(13):111010. Cell Press
Cell reports, 39(13):111010. CELL PRESS
Cell Reports, 39(13)
Cell reports, 39(13):111010. CELL PRESS
Cell Reports, 39(13)
Although transplantation of single genes in yeast plays a key role in elucidating gene functionality in metazoans, technical challenges hamper humanization of full pathways and processes. Empowered by advances in synthetic biology, this study demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f6c37ae17abceac71463ceb4835f8a8
https://research.rug.nl/en/publications/fd1fea1c-43e9-4bf4-94c3-16cc1942d876
https://research.rug.nl/en/publications/fd1fea1c-43e9-4bf4-94c3-16cc1942d876
A supernumerary designer chromosome for modular in vivo pathway assembly in Saccharomyces cerevisiae
Autor:
Pascale Daran-Lapujade, Sofia Dashko, Jean-Marc Daran, Marcel van den Broek, Eline D. Postma, Shannara K. Taylor Parkins, Lars van Breemen
Publikováno v:
Nucleic Acids Research
Nucleic acids research, 49(3)
Nucleic acids research, 49(3)
The construction of microbial cell factories for sustainable production of chemicals and pharmaceuticals requires extensive genome engineering. UsingSaccharomyces cerevisiae, this study proposes Synthetic Chromosomes (SynChs) as orthogonal expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d33dff09d914ea458a9eaf5d328a57ae
https://doi.org/10.1093/nar/gkaa1167
https://doi.org/10.1093/nar/gkaa1167
Publikováno v:
Metabolic Engineering
Metabolic Engineering, 56
Metabolic Engineering, 56
The organic compound 2-phenylethanol (2PE) has a pleasant floral scent and is intensively used in the cosmetic and food industries. Microbial production of 2PE by phenylalanine bioconversion orde novobiosynthesis from sugar offer sustainable, reliabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ab1c609c89af6ff977669c933a20d9
https://doi.org/10.1016/j.ymben.2019.09.011
https://doi.org/10.1016/j.ymben.2019.09.011
Genetic bases for the metabolism of the DMS precursor S-methylmethionine by Saccharomyces cerevisiae
Autor:
Matthias Eder, Isabelle Sanchez, Carole Camarasa, Jean-Marc Daran, Jean-Luc Legras, Sylvie Dequin
Publikováno v:
Food microbiology. 106
Dimethyl sulfide (DMS) is a sulfur containing volatile that enhances general fruity aroma and imparts aromatic notes in wine. The most important precursor of DMS is S-methylmethionine (SMM), which is synthesized by grapes and can be metabolized by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c59e663759d5b7616b241b9c15ec0c
https://pubmed.ncbi.nlm.nih.gov/35690444
https://pubmed.ncbi.nlm.nih.gov/35690444
Publikováno v:
FEMS Yeast Research
FEMS Yeast Research, 21(6)
Perli, T, Borodina, I & Daran, J-M 2021, ' Engineering of molybdenum-cofactor-dependent nitrate assimilation in Yarrowia lipolytica ', FEMS Yeast Research, vol. 21, no. 6, foab050 . https://doi.org/10.1093/femsyr/foab050
FEMS Yeast Research, 21(6)
Perli, T, Borodina, I & Daran, J-M 2021, ' Engineering of molybdenum-cofactor-dependent nitrate assimilation in Yarrowia lipolytica ', FEMS Yeast Research, vol. 21, no. 6, foab050 . https://doi.org/10.1093/femsyr/foab050
Engineering a new metabolic function in a microbial host can be limited by the availability of the relevant cofactor. For instance, in Yarrowia lipolytica, the expression of a functional nitrate reductase is precluded by the absence of molybdenum cof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89625da3fe1426cf6eb9bc8062b57b6a
https://doi.org/10.1093/femsyr/foab050
https://doi.org/10.1093/femsyr/foab050