Zobrazeno 1 - 10 of 43 pro vyhledávání: '"Jean-Luc Rummens"'
1
Akademický článek
Comprehensive antibody and cytokine profiling in hospitalized COVID-19 patients in relation to clinical outcomes in a large Belgian cohort
Autor: Pieter Ruytinx, Patrick Vandormael, Judith Fraussen, Zoë Pieters, Stef Thonissen, Niels Hellings, Piet Stinissen, Ina Callebaut, Joris Penders, Karolien Vanhove, Davy Kieffer, Jean-Luc Rummens, Tom Valkenborgh, Peter Messiaen, Björn Stessel, Dieter Mesotten, Veerle Somers
Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract The immune response in patients with Coronavirus Disease 2019 (COVID-19) is highly variable and is linked to disease severity and mortality. However, antibody and cytokine responses in the early disease stage and their association with disea
Externí odkaz: https://doaj.org/article/0b50942c8d8e4e2086c9b438243cdb49
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2
Akademický článek
Whole-genome sequencing reveals progressive versus stable myeloma precursor conditions as two distinct entities
Autor: Bénedith Oben, Guy Froyen, Kylee H. Maclachlan, Daniel Leongamornlert, Federico Abascal, Binbin Zheng-Lin, Venkata Yellapantula, Andriy Derkach, Ellen Geerdens, Benjamin T. Diamond, Ingrid Arijs, Brigitte Maes, Kimberly Vanhees, Malin Hultcrantz, Elisabet E. Manasanch, Dickran Kazandjian, Alexander Lesokhin, Ahmet Dogan, Yanming Zhang, Aneta Mikulasova, Brian Walker, Gareth Morgan, Peter J. Campbell, Ola Landgren, Jean-Luc Rummens, Niccolò Bolli, Francesco Maura
Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The factors that are associated with myeloma precursor condition progression are not well understood. Here the authors find that monoclonal gammopathies of undetermined significance and smoldering myelomas that did not progress to multiple myelomas h
Externí odkaz: https://doaj.org/article/cf7b932cecac4fc1b4e380aa66de4cb0
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3
Akademický článek
Raising to the Challenge: Building a Federated Biobank to Accelerate Translational Research—The University Biobank Limburg
Autor: Loes Linsen, Kimberly Vanhees, Evi Vanoppen, Kim Ulenaers, Suzanne Driessens, Joris Penders, Veerle Somers, Piet Stinissen, Jean-Luc Rummens
Publikováno v: Frontiers in Medicine, Vol 6 (2019)
Irreproducibility of research results is one of the major contributing factors to the failure of translating basic research results into tangible bedside progress. To address this, the University Biobank Limburg (UBiLim) was founded by a collaboratio
Externí odkaz: https://doaj.org/article/5883906b1df14040836639746a84a71c
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4
Akademický článek
Validation and Application of a Custom-Designed Targeted Next-Generation Sequencing Panel for the Diagnostic Mutational Profiling of Solid Tumors.
Autor: Guy Froyen, An Broekmans, Femke Hillen, Karin Pat, Ruth Achten, Jeroen Mebis, Jean-Luc Rummens, Johan Willemse, Brigitte Maes
Publikováno v: PLoS ONE, Vol 11, Iss 4, p e0154038 (2016)
The inevitable switch from standard molecular methods to next-generation sequencing for the molecular profiling of tumors is challenging for most diagnostic laboratories. However, fixed validation criteria for diagnostic accreditation are not in plac
Externí odkaz: https://doaj.org/article/04e6382cd94b408783919ffa931c36bf
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5
Combinational Therapy of Cardiac Atrial Appendage Stem Cells and Pyridoxamine: The Road to Cardiac Repair?
Autor: Jean-Luc Rummens, Hanne Beliën, Marc Hendrikx, Annelies Bronckaers, Virginie Bito, Sibren Haesen, Sarah D'Haese, Maxim Verboven, Dorien Deluyker, Lize Evens
Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 17
International Journal of Molecular Sciences, Vol 22, Iss 9266, p 9266 (2021)
Myocardial infarction (MI) occurs when the coronary blood supply is interrupted. As a consequence, cardiomyocytes are irreversibly damaged and lost. Unfortunately, current therapies for MI are unable to prevent progression towards heart failure. As t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42bdc5a6ce85c5d19acbcde65c37d335
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6
Muscle wasting after coronary artery bypass graft surgery: impact on post-operative clinical status and effect of exercise-based rehabilitation
Autor: Kenneth Verboven, Paul Dendale, Jean-Luc Rummens, Hajar Boujemaa, Ines Frederix, Dominique Hansen, Bert O. Eijnde, Marc Hendrikx
Publikováno v: Acta cardiologica
Background:Coronary artery bypass graft (CABG) surgery is known to induce significant muscle wasting. It remains to be investigated whether muscle wasting after CABG surgery relates to a worse clinical status at entry of rehabilitation and exercise-b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc1fd8d0820bae94ba72d2a1da4a84c
https://doi.org/10.1080/00015385.2019.1598035
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7
Whole-genome sequencing reveals progressive versus stable myeloma precursor conditions as two distinct entities
Autor: Kylee H Maclachlan, Brigitte Maes, Aneta Mikulasova, Guy Froyen, Ahmet Dogan, Federico Abascal, Andriy Derkach, Peter J. Campbell, Benjamin Diamond, Binbin Zheng-Lin, Ellen Geerdens, Kimberly Vanhees, Jean Luc Rummens, Bénedith Oben, Gareth J. Morgan, Francesco Maura, Ola Landgren, Niccolo Bolli, Ingrid Arijs, Malin Hultcrantz, Elisabet E. Manasanch, Daniel Leongamornlert, Venkata Yellapantula, Brian A Walker, Dickran Kazandjian, Yanming Zhang, Alexander M. Lesokhin
Publikováno v: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Multiple myeloma (MM) is consistently preceded by precursor conditions recognized clinically as monoclonal gammopathy of undetermined significance (MGUS) or smoldering myeloma (SMM). We interrogate the whole genome sequence (WGS) profile of 18 MGUS a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3631e392abe51c275402a648eb8794
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8
Advanced Glycation End Products Impair Cardiac Atrial Appendage Stem Cells Properties
Autor: Dorien Deluyker, Lize Evens, Marc Hendrikx, Ellen Heeren, Virginie Bito, Jean-Luc Rummens, Annelies Bronckaers
Publikováno v: Journal of Clinical Medicine, Vol 10, Iss 2964, p 2964 (2021)
Journal of Clinical Medicine
Volume 10
Issue 13
Background: During myocardial infarction (MI), billions of cardiomyocytes are lost. The optimal therapy should effectively replace damaged cardiomyocytes, possibly with stem cells able to engraft and differentiate into adult functional cardiomyocytes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7d72c10dc53ed99b363ae80eacd7634
http://hdl.handle.net/1942/36311
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10
Differentiation of Human Cardiac Atrial Appendage Stem Cells into Adult Cardiomyocytes: A Role for the Wnt Pathway?
Autor: Annick Daniëls, Loes Linsen, Leen Willems, Virginie Bito, Marc Hendrikx, Yanick Fanton, Karen Hensen, Lize Evens, Jean-Luc Rummens, Jeroen Declercq
Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 11
International Journal of Molecular Sciences, Vol 21, Iss 3931, p 3931 (2020)
Human cardiac stem cells isolated from atrial appendages based on aldehyde dehydrogenase activity (CASCs) can be expanded in vitro and differentiate into mature cardiomyocytes. In this study, we assess whether Wnt activation stimulates human CASC pro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ba4eb9fb7029f8b62b747ed79cfd94
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