Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Jean-Luc Plantier"'
Autor:
Toufik Abache, Alexandre Fontayne, Dominique Grenier, Emilie Jacque, Alain Longue, Anne-Sophie Dezetter, Béatrice Souilliart, Guillaume Chevreux, Damien Bataille, Sami Chtourou, Jean-Luc Plantier
Publikováno v:
Haematologica, Vol 105, Iss 9 (2019)
Rendering coagulation factor X sensitive to thrombin was proposed as a strategy that can bypass the need for factor VIII. In this paper, this non-replacement strategy was evaluated in vitro and in vivo in its ability to correct factor VIII but also f
Externí odkaz:
https://doaj.org/article/3c7f6950972a4ce1a68112eb78c086be
Publikováno v:
Haemophilia
Introduction/Aim Eptacog beta is a recombinant activated human factor VII approved to treat and control bleeding in haemophilia A and B patients with inhibitors. Emicizumab is a factor VIIIa mimetic antibody approved for prophylactic treatment of hae
Autor:
Anne-Sophie Dezetter, Damien Bataille, Béatrice Souilliart, Alain Longue, Toufik Abache, Dominique Grenier, Emilie Jacque, Guillaume Chevreux, Sami Chtourou, Alexandre Fontayne, Jean-Luc Plantier
Publikováno v:
Haematologica
Rendering coagulation factor X sensitive to thrombin was proposed as a strategy to bypass the need for factor VIII. In this study, this nonreplacement strategy was evaluated in vitro and in vivo for its ability to correct factor VIII but also factor
Publikováno v:
Thrombosis Research. 167:88-95
Antithrombin (AT) binds in vitro and in vivo to endothelial cells through various receptors, including heparan sulphate glycosaminoglycan (HSPG) that could modulate the AT activity. A thrombin generation assay (TGA) was set up at the surface of HUVEC
Autor:
Veronique Duretz, Sean Evans, Michael Recht, Robert F. Sidonio, Michael U. Callaghan, Daniel Bonzo, Cédric Hermans, Steven W. Pipe, Jean Luc Plantier, Ian S Mitchell, Jerry A Grandoni
Publikováno v:
Blood. 136:41-42
Introduction Eptacog beta [Sevenfact®, coagulation factor VIIa (recombinant)-jncw] (HEMA Biologics and LFB) is a human rFVIIa variant indicated for the treatment and control of bleeding events (BEs) in adults and adolescents with hemophilia A or B a
Autor:
Jean-Luc Plantier, Alexandre Sebestyen, Vincent Richard, Alexandre Fontayne, Toufik Abache, Fabien Doguet, Elsa P. Bianchini, Yasmine Bourti, Fabienne Tamion, Delphine Borgel
Publikováno v:
British Journal of Haematology
British Journal of Haematology, Wiley, 2018, 180 (5), pp.715-720. ⟨10.1111/bjh.15091⟩
British Journal of Haematology, 2018, 180 (5), pp.715-720. ⟨10.1111/bjh.15091⟩
British Journal of Haematology, Wiley, 2018, 180 (5), pp.715-720. ⟨10.1111/bjh.15091⟩
British Journal of Haematology, 2018, 180 (5), pp.715-720. ⟨10.1111/bjh.15091⟩
International audience; Heparin anticoagulation followed by protamine reversal is commonly used in cardiopulmonary bypass (CPB). As an alternative to protamine, a recombinant inactive antithrombin (riAT) was designed as an antidote to heparin and was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0842c250ae2e982810f279eafaeb9093
https://www.hal.inserm.fr/inserm-02296615/file/Bianchini_et_al-2018-British_Journal_of_Haematology.pdf
https://www.hal.inserm.fr/inserm-02296615/file/Bianchini_et_al-2018-British_Journal_of_Haematology.pdf
Autor:
Marc Delcourt, Jean-Luc Pellequer, Jean-Luc Plantier, Didier Saboulard, Claude Negrier, Shu-wen W. Chen
Publikováno v:
Thrombosis and Haemostasis
Thrombosis and Haemostasis, 2017, 106 (07), pp.121-131. ⟨10.1160/TH10-09-0572⟩
Thrombosis and Haemostasis, Schattauer, 2017, 106 (07), pp.121-131. ⟨10.1160/TH10-09-0572⟩
Thrombosis and Haemostasis, 2017, 106 (07), pp.121-131. ⟨10.1160/TH10-09-0572⟩
Thrombosis and Haemostasis, Schattauer, 2017, 106 (07), pp.121-131. ⟨10.1160/TH10-09-0572⟩
SummaryThe factor VIII (FVIII) is a cofactor of the coagulation cascade. The FVIII C2 domain is a critical domain that participates in the interactions with the von Willebrand factor and the phospholipidic surfaces. To assess the importance of each r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54dabd6fed97397aa1b9685140bf4d4e
https://hal.univ-grenoble-alpes.fr/hal-03244084
https://hal.univ-grenoble-alpes.fr/hal-03244084
Autor:
François Saller, Anne-Lise Marie, Toufik Abache, Delphine Borgel, Rémi Urbain, Nguyet Thuy Tran, Myriam Taverna, Stéphane Pautus, Jean-Luc Plantier, Elsa P. Bianchini
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 111:64-70
With the aim to determine the binding affinity of a new generation of recombinant antithrombin (AT) toward heparin, we developed a dynamic equilibrium-affinity capillary electrophoresis (DE-ACE) method. This method allows the determination of an AT-h
Publikováno v:
Biologicals : journal of the International Association of Biological Standardization. 44(4)
Albumin displays several important functions for homeostasis amongst which the maintenance of the plasma redox-state. The study aim was to compare the redox state of pharmaceutical human albumin preparations since it reflects the oxidation-reduction
Autor:
Rémi Urbain, N. Thuy Tran, François Saller, Jean-Luc Plantier, Myriam Taverna, Elena Domínguez-Vega, Anne-Lise Marie, Delphine Borgel, Govert W. Somsen
Publikováno v:
Marie, A L, Dominguez Vega, E, Saller, F, Plantier, J-L, Urbain, R, Borgel, D, Tran, N T, Somsen, G W & Taverna, M 2016, ' Characterization of conformers and dimers of antithrombin by capillary elctrophoresis-quadrupole-time-of-flight mass spectrometry. ', Analytica Chimica Acta, vol. 947, pp. 58-65 . https://doi.org/10.1016/j.aca.2016.10.016
Analytica Chimica Acta, 947, 58-65. Elsevier
Analytica Chimica Acta, 947, 58-65. Elsevier
Antithrombin (AT) is a plasma glycoprotein which possesses anticoagulant and anti-inflammatory properties. AT exhibits various forms, among which are native, latent and heterodimeric ones. We studied the potential of capillary electrophoresis-mass sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa2bc21827c030c76db66800c188bbd
https://research.vu.nl/en/publications/f478f304-99f7-4a6d-bbf4-6c554de00b49
https://research.vu.nl/en/publications/f478f304-99f7-4a6d-bbf4-6c554de00b49