Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Jean-Luc Jestin"'
Autor:
Pablo Guardado-Calvo, Eduardo A Bignon, Eva Stettner, Scott Allen Jeffers, Jimena Pérez-Vargas, Gerard Pehau-Arnaudet, M Alejandra Tortorici, Jean-Luc Jestin, Patrick England, Nicole D Tischler, Félix A Rey
Publikováno v:
PLoS Pathogens, Vol 12, Iss 10, p e1005813 (2016)
Hantaviruses are zoonotic viruses transmitted to humans by persistently infected rodents, giving rise to serious outbreaks of hemorrhagic fever with renal syndrome (HFRS) or of hantavirus pulmonary syndrome (HPS), depending on the virus, which are as
Externí odkaz:
https://doaj.org/article/aff89a5f7320477bbd967b158f670a81
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 7, Iss 9, p e201305001 (2013)
There is a need for rules allowing three-dimensional structure information to be derived from protein sequences. In this work, consideration of an elementary protein folding step allows protein sub-sequences which optimize folding to be derived for a
Externí odkaz:
https://doaj.org/article/b4407ef5f32a456db26d66e9529609be
Autor:
Jean-Luc Jestin
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 2, Iss 3 (2012)
A general strategy for the isolation of catalysts for given chemical reactions was designed. A first link between genes and their corresponding proteins was established by phage display: using Darwin's principles on evolution based on selection and a
Externí odkaz:
https://doaj.org/article/38208c44da554f7c8e386596541feccb
Autor:
Jean-Luc Jestin, Bernard Caudron
Publikováno v:
Journal of Biophysical Chemistry
Journal of Biophysical Chemistry, 2014, 05 (01), pp.5-12. ⟨10.4236/jbpc.2014.51002⟩
Journal of Biophysical Chemistry, 2014, 05 (01), pp.5-12. ⟨10.4236/jbpc.2014.51002⟩
International audience; Using a statistical analysis on beta-sheet structures from the Protein Data Bank, characteristic angles within beta-strands were correlated to the nature of the side chains. The twists were computed from the atomic coordinates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c022941d433861602aa60599c10db1d3
https://doi.org/10.4236/jbpc.2014.51002
https://doi.org/10.4236/jbpc.2014.51002
Publikováno v:
Applied Mathematics. :79-89
A general and elementary protein folding step was described in a previous article. Energy conservation during this folding step yielded an equation with remarkable solutions over the field of rational numbers. Sets of sequences optimized for folding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e51b359ea05c807ecd02d9d0459d0a28
https://doi.org/10.4236/am.2014.51009
https://doi.org/10.4236/am.2014.51009
Autor:
Pierre Lafaye, Laurence Damier-Piolle, Félix A. Rey, Alexander W. Tarr, Jane A. McKeating, Richard J. C. Brown, Luke W. Meredith, Jean-Luc Jestin, Annalisa Meola, Richard A. Urbanowicz, Thomas Krey, Jonathan K. Ball
Publikováno v:
Hepatology. 58:932-939
Severe liver disease caused by chronic hepatitis C virus is the major indication for liver transplantation. Despite recent advances in antiviral therapy, drug toxicity and unwanted side effects render effective treatment in liver-transplanted patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5851fde0afa4bd6403a3bb50328fa3e2
https://doi.org/10.1002/hep.26430
https://doi.org/10.1002/hep.26430
Autor:
Dorothée Moisy, Florence Baudin, Jean-Luc Jestin, Yves Jacob, Brı́d M. Laoide, Nadia Naffakh, Sergiy V. Avilov, Xingyi Ge
Publikováno v:
Journal of Virology; Vol 86
Influenza virus has evolved replication strategies that hijack host cell pathways. To uncover interactions between viral macromolecules and host proteins, we applied a phage display strategy. A library of human cDNA expression products displayed on f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce340956b02486adc6f63b26f88824ae
https://doi.org/10.1128/jvi.00789-12
https://doi.org/10.1128/jvi.00789-12
Autor:
Antonin Guilloux, Jean-Luc Jestin
Publikováno v:
Biosystems. 109:141-144
Why is the genetic code the way it is? Concepts from fields as diverse as molecular evolution, classical chemistry, biochemistry and metabolism have been used to define selection pressures most likely to be involved in the shaping of the genetic code
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b184be2d3663d39c5c09999375385eb8
https://doi.org/10.1016/j.biosystems.2012.03.001
https://doi.org/10.1016/j.biosystems.2012.03.001
Autor:
Jean-Luc Jestin, Sophie Vichier-Guerre
Publikováno v:
Molecular Biotechnology. 46:58-62
Phage display establishes a link between a polypeptide and its corresponding gene. It has been much used for the isolation of proteins binding to chosen molecular targets. A second link was designed more recently between a phage-displayed enzyme and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1c53d34fcdc12a0b4f174e97c703ab
https://doi.org/10.1007/s12033-010-9275-4
https://doi.org/10.1007/s12033-010-9275-4
Autor:
Jean-Luc Jestin, Fariborz Bahrami
Publikováno v:
Biochimie. 90:1796-1799
Genome annotations result generally from large sequence alignments by bioinformatics. Large scale biochemical data are more difficult to obtain. They derive for example from directed protein evolution experiments by selection. A previously reported d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de55c54f7bf60f4b0307f6e1160c3f24
https://doi.org/10.1016/j.biochi.2008.07.006
https://doi.org/10.1016/j.biochi.2008.07.006