Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Jean-Louis Pujol"'
Autor:
Jean-Louis Pujol, MD, PhD, Grégoire Mercier, MD, PhD, Maria Vasile, MCS, Isabelle Serre, MD, PhD, Hélène Vernhet-Kovacsik, MD, PhD, Sébastien Bommart, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 4, Iss 6, Pp 100526- (2023)
Guidelines for optimal timing of lung cancer diagnosis and treatment have been implemented in many countries, but the effect of fast-track interventions on the shortening of time interval is still debatable. In this study, the delay from the first sp
Externí odkaz:
https://doaj.org/article/be5fa10ccb474503a25308361debcf48
Autor:
Jean-Louis Pujol, MD, PhD, Johan Vansteenkiste, MD, PhD, Luis Paz-Ares Rodríguez, MD, PhD, Vanesa Gregorc, MD, Julien Mazieres, MD, PhD, Mark Awad, MD, PhD, Pasi A. Jänne, MD, PhD, Michael Chisamore, PhD, Anwar M. Hossain, MStat, Yanyun Chen, PhD, J. Thaddeus Beck, MD, FACP
Publikováno v:
JTO Clinical and Research Reports, Vol 2, Iss 11, Pp 100234- (2021)
Introduction: Abemaciclib is an oral, selective small-molecule CDK 4 and 6 inhibitor. In preclinical models, abemaciclib synergized with programmed cell death protein-1 blockade to enhance antitumor efficacy. Here, we report the safety and anticancer
Externí odkaz:
https://doaj.org/article/c9caff189596499fa7e9767a030f2c97
Autor:
Elodie Negre, MD, Amandine Coffy, BSc, Alexandra Langlais, BSc, Jean-Pierre Daures, MD, PhD, Armelle Lavole, MD, Elisabeth Quoix, MD, PhD, Olivier Molinier, MD, Laurent Greillier, MD, PhD, Clarisse Audigier-Valette, MD, Denis Moro-Sibilot, MD, PhD, Virginie Westeel, MD, PhD, Franck Morin, PhD, Benoît Roch, MD, Jean-Louis Pujol, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 1, Iss 1, Pp 100016- (2020)
Introduction: This study aimed at generating a new simplified prognostic score (SPS) using common clinical and biological variables to discriminate a limited number of subgroups of patients with SCLC differing by their overall survival (OS). Methods:
Externí odkaz:
https://doaj.org/article/1cc090aaaba44673962212a5da2c6435
Autor:
Jean-Louis Pujol, Amandine Coffy, Andrea Camerini, Athanasios Kotsakis, Manlio Mencoboni, Milena Gusella, Felice Pasini, Aldo Pezzuto, Giuseppe Luigi Banna, Cemil Bilir, Epaminontas Samantas, Fabrice Barlesi, Benoît Roch, Aude Guillou, Jean-Pierre Daurès
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220988 (2019)
IntroductionSeveral non-comparative phase II studies have evaluated metronomic oral vinorelbine (MOV) in metastatic non-small cell lung cancer (NSCLC) but the small size of each study limits their conclusions.PurposeTo perform an individual patient-d
Externí odkaz:
https://doaj.org/article/b5339a305a1c47c1b98a8dc3e327c8f9
Autor:
Guillaume Herbreteau, Alexandra Langlais, Laurent Greillier, Clarisse Audigier-Valette, Lionel Uwer, José Hureaux, Denis Moro-Sibilot, Florian Guisier, Delphine Carmier, Jeannick Madelaine, Josiane Otto, Pierre-Jean Souquet, Valérie Gounant, Patrick Merle, Olivier Molinier, Aldo Renault, Audrey Rabeau, Franck Morin, Marc G Denis, Jean-Louis Pujol
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 12, p 3861 (2020)
Background: The IFCT-1603 trial evaluated atezolizumab in small cell lung cancer (SCLC). The purpose of the present study was to determine whether circulating tumor DNA (ctDNA), prospectively collected at treatment initiation, was associated with the
Externí odkaz:
https://doaj.org/article/858798049fc34b94b1313b6dc5af7b01
Autor:
Fatéméh Dubois, Maureen Keller, Julien Hoflack, Elodie Maille, Martine Antoine, Virginie Westeel, Emmanuel Bergot, Elisabeth Quoix, Armelle Lavolé, Laurence Bigay-Game, Jean-Louis Pujol, Alexandra Langlais, Franck Morin, Gérard Zalcman, Guénaëlle Levallet
Publikováno v:
Cancers, Vol 11, Iss 12, p 1835 (2019)
RASSF1 gene methylation predicts longer disease-free survival (DFS) and overall survival (OS) in patients with early-stage non-small-cell lung cancer treated using paclitaxel-based neo-adjuvant chemotherapy compared to patients receiving a gemcitabin
Externí odkaz:
https://doaj.org/article/366b494eb7834db3b05d12b871fc41a0
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197605 (2018)
OBJECTIVE:Treatment failures in advanced lung cancer are frequent events affecting patients during or after first-line chemotherapy. International guidelines recommend second-line chemotherapy. However, around one half of patients who experience dise
Externí odkaz:
https://doaj.org/article/d55fe70d9cde4b6bb626163d4a422cad
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128836 (2015)
Human epididymis secretory protein 4 (HE4) is a secreted glycosylated protein encoded by the WAP four-disulfide core domain 2 (WFDC2) gene, located on a chromosome 20 segment that is frequently amplified in many cancers. This study aimed at determini
Externí odkaz:
https://doaj.org/article/cd2cd8ce6d1f4357a97f28054ac7a20c
Autor:
Pierre, Mordant, Solenn, Brosseau, Bernard, Milleron, Nicola, Santelmo, Séverine, Fraboulet-Moreau, Benjamin, Besse, Alexandra, Langlais, Dominique, Gossot, Pascal-Alexandre, Thomas, Jean-Louis, Pujol, Charles, Ricordel, Jeannick, Madelaine, Régine, Lamy, Clarisse, Audigier-Valette, Pascale, Missy, Hélène, Blons, Fabrice, Barlesi, Virginie, Westeel
Publikováno v:
Clinical Lung Cancer
Clinical Lung Cancer, 2023, 24 (1), pp.1-10. ⟨10.1016/j.cllc.2022.08.013⟩
Clinical Lung Cancer, 2023, 24 (1), pp.1-10. ⟨10.1016/j.cllc.2022.08.013⟩
International audience; INTRODUCTION: Molecular profile of resected stage I-II non-small cell lung cancer (NSCLC) would help refine prognosis and personalize induction or adjuvant strategies. We sought to report the molecular profile of resected stag
Autor:
Gérard Zalcman, Jacques Camonis, Denis Moro-Sibilot, Jean-Louis Pujol, Isabelle Rouquette, Fatéméh Dubois, Didier Debieuvre, Elisabeth Quoix, Marie Wislez, Virginie Westeel, Franck Morin, Jérôme Levallet, Elisabeth Brambilla, Florence de Fraipont, Michelle Beau-Faller, Adriana O. Santos, Christian Creveuil, Martine Antoine, Emmanuel Bergot, Guénaëlle Levallet
PDF file - 56K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb8e04f3d01f15d1d9503653c3f0114
https://doi.org/10.1158/1535-7163.22497352
https://doi.org/10.1158/1535-7163.22497352