Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jean-Louis Palgen"'
Autor:
Evgueni Jacob, Angélique Perrillat-Mercerot, Jean-Louis Palgen, Adèle L’Hostis, Nicoletta Ceres, Jean-Pierre Boissel, Jim Bosley, Claudio Monteiro, Riad Kahoul
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-21 (2023)
Abstract Background Over the past several decades, metrics have been defined to assess the quality of various types of models and to compare their performance depending on their capacity to explain the variance found in real-life data. However, avail
Externí odkaz:
https://doaj.org/article/c6d6264f33964736972803ca1fa4a9c7
Autor:
Adèle L’Hostis, Jean-Louis Palgen, Angélique Perrillat-Mercerot, Emmanuel Peyronnet, Evgueni Jacob, James Bosley, Michaël Duruisseaux, Raphaël Toueg, Lucile Lefèvre, Riad Kahoul, Nicoletta Ceres, Claudio Monteiro
Publikováno v:
npj Systems Biology and Applications, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract Lung adenocarcinoma (LUAD) is associated with a low survival rate at advanced stages. Although the development of targeted therapies has improved outcomes in LUAD patients with identified and specific genetic alterations, such as activating
Externí odkaz:
https://doaj.org/article/3e54093f844f49948535eddc19fa9f5f
Autor:
Hippolyte Darré, Perrine Masson, Arnaud Nativel, Laura Villain, Diane Lefaudeux, Claire Couty, Bastien Martin, Evgueni Jacob, Michaël Duruisseaux, Jean-Louis Palgen, Claudio Monteiro, Adèle L’Hostis
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 704 (2024)
Mutationsin epidermal growth factor receptor (EGFR) are found in approximately 48% of Asian and 19% of Western patients with lung adenocarcinoma (LUAD), leading to aggressive tumor growth. While tyrosine kinase inhibitors (TKIs) like gefitinib and os
Externí odkaz:
https://doaj.org/article/e5edff8536c445b9bec0eb00a9ed4bd5
Autor:
Curtis Cai, Jerome Samir, Mehdi R. Pirozyan, Thiruni N. Adikari, Money Gupta, Preston Leung, Brendan Hughes, Willem Van der Byl, Simone Rizzetto, Auda Elthala, Elizabeth Keoshkerian, Jean-Louis Palgen, Timothy Peters, Thi H. O. Nguyen, Raymond Louie, Katherine Kedzierska, Silvana Gaudieri, Rowena A. Bull, Andrew R. Lloyd, Fabio Luciani
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The early immune response following exposure to HCV is not fully explored. Here the authors use single cell analysis and immune profiling to relate the infection sequence and immune response to early HCV infection showing that exhausted phenotypes of
Externí odkaz:
https://doaj.org/article/588f772ffcbf4737b2226e6c72bd6b81
Autor:
Antoine Rousseau, Oscar Haigh, Roger Legrand, Jean-Louis Palgen, Julien Lemaitre, Claire Deback, Noémie Oziol, Patrick Lomonte, Marc Labetoulle
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Primary infection with herpes simplex type 1 (HSV-1) occurring around the mouth and nose switches rapidly to lifelong latent infection in sensitive trigeminal ganglia (TG) neurons. Sporadic reactivation of these latent reservoirs later in li
Externí odkaz:
https://doaj.org/article/759feb6d36e04fe28cf79e556fcd4273
Autor:
Yanis Feraoun, Jean-Louis Palgen, Candie Joly, Nicolas Tchitchek, Ernesto Marcos-Lopez, Nathalie Dereuddre-Bosquet, Anne-Sophie Gallouet, Vanessa Contreras, Yves Lévy, Frédéric Martinon, Roger Le Grand, Anne-Sophie Beignon
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Innate immunity modulates adaptive immunity and defines the magnitude, quality, and longevity of antigen-specific T- and B- cell immune memory. Various vaccine and administration factors influence the immune response to vaccination, including the rou
Externí odkaz:
https://doaj.org/article/4e8d67227a834e9ea0caf0bc8cc56a37
Autor:
Jean-Louis Palgen, Yanis Feraoun, Gaëlle Dzangué-Tchoupou, Candie Joly, Frédéric Martinon, Roger Le Grand, Anne-Sophie Beignon
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Most vaccines require multiple doses to induce long-lasting protective immunity in a high frequency of vaccines, and to ensure strong both individual and herd immunity. Repetitive immunogenic stimulations not only increase the intensity and durabilit
Externí odkaz:
https://doaj.org/article/1fdda03a6e724539992f0e1fc027b389
Autor:
Nicolas Huot, Philippe Rascle, Caroline Petitdemange, Vanessa Contreras, Jean-Louis Palgen, Christiane Stahl-Hennig, Roger Le Grand, Anne-Sophie Beignon, Beatrice Jacquelin, Michaela Müller-Trutwin
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Natural killer (NK) cells play essential roles in immunity to viruses and tumors. Their function is genetically determined but also modulated by environmental factors. The distribution and functional regulation of these cells vary depending on the ti
Externí odkaz:
https://doaj.org/article/74cb0d2463a34ce1b9a869ea2cf83272
Autor:
Adèle L'Hostis, Jean-Louis Palgen, Angélique Perrillat-Mercerot, Emmanuel Peyronnet, Evgueni Jacob, James R. Bosley, Michaël Duruisseaux, Raphaël Toueg, Lucile Lefèvre, Riad Kahoul, Nicoletta Ceres, Claudio Monteiro
Lung adenocarcinoma (LUAD) is associated with a low survival rate at advanced stages. Although the development of targeted therapies has improved the survival of LUAD patients with identified and specific genetic alterations, such as mutations on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83a4196c81bb29689085789ae8f8c3a0
https://doi.org/10.21203/rs.3.rs-2405647/v1
https://doi.org/10.21203/rs.3.rs-2405647/v1
Autor:
Evgueni Jacob, Angélique Perrillat-Mercerot, Jean-Louis Palgen, Adèle L’Hostis, Nicoletta Ceres, Jean-Pierre Boissel, Jim Bosley, Claudio Monteiro, Riad Kahoul
Over the past several decades, metrics have been defined to assess the quality of various types of models and to compare their performance depending on their capacity to explain the variance found in real-life data. However, available validation meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87511a0f055355da9c781ea980b397ab
https://doi.org/10.1101/2022.09.08.507079
https://doi.org/10.1101/2022.09.08.507079