Zobrazeno 1 - 10
of 242
pro vyhledávání: '"Jean-Louis Guénet"'
Publikováno v:
Genetics and Molecular Biology, Vol 28, Iss 2, Pp 201-204 (2005)
The Paralysé mutation is a spontaneous neuromuscular mutation, first observed in 1980 at the Pasteur Institute, which is transmitted by the autosomal recessive par allele. Affected homozygote par/par mice rarely survive beyond 16 days of age and at
Externí odkaz:
https://doaj.org/article/243bd168fda94ca2971b8f3d90fbd45f
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 3, Pp 447-458 (2001)
The frissonnant (fri) mutation is an autosomic recessive mutation which spontaneously appeared in the stock of C3H mice. fri mutant mice have locomotor instability and rapid tremor. Since tremor ceases when mutant mice have sleep or are anaesthetized
Externí odkaz:
https://doaj.org/article/fb8494878ed04c85a8646ae98fdd2124
Autor:
Georg Steffes, Beatriz Lorente-Cánovas, Selina Pearson, Rachael H Brooker, Sarah Spiden, Amy E Kiernan, Jean-Louis Guénet, Karen P Steel
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e51065 (2012)
Mutanlallemand (mtl) and Belly Spot and Deafness (bsd) are two new spontaneous alleles of the Lmx1a gene in mice. Homozygous mutants show head tossing and circling behaviour, indicative of vestibular defects, and they have short tails and white belly
Externí odkaz:
https://doaj.org/article/463643acdb0c45af869718d1e1c8efc9
Autor:
Fabian Runkel, Maik Hintze, Sebastian Griesing, Marion Michels, Birgit Blanck, Kiyoko Fukami, Jean-Louis Guénet, Thomas Franz
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39203 (2012)
BACKGROUND: Inositol 1,4,5trisphosphate (IP(3)) and diacylglycerol (DAG) are important intracellular signalling molecules in various tissues. They are generated by the phospholipase C family of enzymes, of which phospholipase C delta (PLCD) forms one
Externí odkaz:
https://doaj.org/article/190013592a114fa69053ca422da8af41
A mutation in the gene encoding mitochondrial Mg²+ channel MRS2 results in demyelination in the rat.
Autor:
Takashi Kuramoto, Mitsuru Kuwamura, Satoko Tokuda, Takeshi Izawa, Yoshifumi Nakane, Kazuhiro Kitada, Masaharu Akao, Jean-Louis Guénet, Tadao Serikawa
Publikováno v:
PLoS Genetics, Vol 7, Iss 1, p e1001262 (2011)
The rat demyelination (dmy) mutation serves as a unique model system to investigate the maintenance of myelin, because it provokes severe myelin breakdown in the central nervous system (CNS) after normal postnatal completion of myelination. Here, we
Externí odkaz:
https://doaj.org/article/32f36d506792456791f4c80dbbe0fd47
Autor:
Tomoji Mashimo, Ouadah Hadjebi, Fabiola Amair-Pinedo, Toshiko Tsurumi, Francina Langa, Tadao Serikawa, Constantino Sotelo, Jean-Louis Guénet, Jose Luis Rosa
Publikováno v:
PLoS Genetics, Vol 5, Iss 12, p e1000784 (2009)
The HERC gene family encodes proteins with two characteristic domains: HECT and RCC1-like. Proteins with HECT domains have been described to function as ubiquitin ligases, and those that contain RCC1-like domains have been reported to function as GTP
Externí odkaz:
https://doaj.org/article/880f18f25df347529906118c33c6e8fa
Autor:
Jean-Louis Guénet
Publikováno v:
Périodiques Scientifiques en Édition Électronique.
Using modern DNA engineering techniques, geneticists are now able to precisely alter the genomic structure of domestic animals and, in order to describe these kinds of changes, it has become common to speak of " gene or genomic editing". In most case
Autor:
Fernando Benavides, Jean-Louis Guénet
Publikováno v:
Experimental Design and Reproducibility in Preclinical Animal Studies ISBN: 9783030661465
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1db133bde9efe7f87856ed89a171fec6
https://doi.org/10.1007/978-3-030-66147-2_2
https://doi.org/10.1007/978-3-030-66147-2_2
Autor:
John DiGiovanni, Gyu Song, Lars Mecklenburg, Alexsandra Espejo, Richard D. Wood, Jean Louis Guénet, Jean Jaubert, Marcela Del Rio, Donna F. Kusewitt, Claudio J. Conti, Fernando Benavides, Lucía Martínez-Santamaría, Sharon Y.R. Dent, Eleonora Napoli, Cecilia R Giulivi, Carlos J. Perez, Brian M. Iritani, Mark T. Bedford
Publikováno v:
Journal of Investigative Dermatology
Journal of Investigative Dermatology, Nature Publishing Group, 2015, 135 (12), pp.3133-3143. ⟨10.1038/jid.2015.314⟩
The Journal of investigative dermatology
The Journal of investigative dermatology, vol 135, iss 12
Journal of Investigative Dermatology, 2015, 135 (12), pp.3133-3143. ⟨10.1038/jid.2015.314⟩
Journal of Investigative Dermatology, Nature Publishing Group, 2015, 135 (12), pp.3133-3143. ⟨10.1038/jid.2015.314⟩
The Journal of investigative dermatology
The Journal of investigative dermatology, vol 135, iss 12
Journal of Investigative Dermatology, 2015, 135 (12), pp.3133-3143. ⟨10.1038/jid.2015.314⟩
International audience; Here we describe a spontaneous mutation in the Zdhhc13 (zinc finger, DHHC domain containing 13) gene (also called Hip14l), one of 24 genes encoding palmitoyl acyltransferase (PAT) enzymes in the mouse. This mutation (Zdhhc13lu