Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jean-Louis A. Parmasad"'
Autor:
Jean-Louis A. Parmasad, Konrad M. Ricke, Benjamin Nguyen, Morgan G. Stykel, Brodie Buchner-Duby, Amanda Bruce, Haley M. Geertsma, Eric Lian, Nathalie A. Lengacher, Steve M. Callaghan, Alvin Joselin, Julianna J. Tomlinson, Michael G. Schlossmacher, William L. Stanford, Jiyan Ma, Patrik Brundin, Scott D. Ryan, Maxime W. C. Rousseaux
Publikováno v:
Cell Death and Disease, Vol 15, Iss 4, Pp 1-13 (2024)
Abstract Parkinson’s disease (PD) is a debilitating neurodegenerative disease characterized by the loss of midbrain dopaminergic neurons (DaNs) and the abnormal accumulation of α-Synuclein (α-Syn) protein. Currently, no treatment can slow nor hal
Externí odkaz:
https://doaj.org/article/3314777d4067426182b748c43099f849
Autor:
Terry R. Suk, Trina T. Nguyen, Zoe A. Fisk, Miso Mitkovski, Haley M. Geertsma, Jean-Louis A. Parmasad, Meghan M. Heer, Steve M. Callaghan, Nils Brose, Marilyn Tirard, Maxime W.C. Rousseaux
Publikováno v:
bioRxiv
SUMOylation is an evolutionarily conserved and essential mechanism whereby Small Ubiquitin Like Modifiers, or SUMO proteins (Sumo in mice), are covalently bound to protein substrates in a highly dynamic and reversible manner. SUMOylation is involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0d0b3b17bab0dd3d7e8ba5f4db053d
https://doi.org/10.1101/2022.09.09.507035
https://doi.org/10.1101/2022.09.09.507035
Autor:
Kyra Horsthuis, Konrad M. Ricke, Haley M. Geertsma, Zoe Fisk, Terry R. Suk, Maxime W.C. Rousseaux, Jean-Louis A. Parmasad, Steve M. Callaghan
BackgroundA growing body of evidence suggests that nuclear alpha-synuclein (αSyn) plays a role in the pathogenesis of Parkinson’s disease (PD). However, this question has been difficult to address as controlling the localization of αSyn in experi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c7abd24cf1ec676d82ee6b8a8fd599f
https://doi.org/10.1101/2021.10.13.464123
https://doi.org/10.1101/2021.10.13.464123