Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Jean-Léon Thomas"'
Autor:
Maïté Verreault, Irma Segoviano Vilchis, Shai Rosenberg, Nolwenn Lemaire, Charlotte Schmitt, Jérémy Guehennec, Louis Royer‐Perron, Jean‐Léon Thomas, TuKiet T. Lam, Florent Dingli, Damarys Loew, François Ducray, Sophie Paris, Catherine Carpentier, Yannick Marie, Florence Laigle‐Donadey, Audrey Rousseau, Natascha Pigat, Florence Boutillon, Franck Bielle, Karima Mokhtari, Stuart J. Frank, Aurélien deReyniès, Khê Hoang‐Xuan, Marc Sanson, Vincent Goffin, Ahmed Idbaih
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 7, Pp n/a-n/a (2022)
Abstract Objective New therapeutic approaches are needed to improve the prognosis of glioblastoma (GBM) patients. Methods With the objective of identifying alternative oncogenic mechanisms to abnormally activated epidermal growth factor receptor (EGF
Externí odkaz:
https://doaj.org/article/eda0001ce8334a88897701a1bbcf3626
Autor:
Ligia Simoes Braga Boisserand, Seyoung Lee, Jean Bouchart, Luiz Henrique Medeiros Geraldo, Basavaraju Sanganahalli, Anne Eichmann, Lauren H Sansing, Helene Benveniste, Fahmeed Hyder, Jean-Léon Thomas
Publikováno v:
Stroke. 54
Meningeal lymphatic vessels (MLVs) promote clearance and immune surveillance of central nervous system (CNS) 1 tissue. Vascular Endothelium Growth Factor-C (VEGF-C) regulates meningeal lymphatic growth and has shown therapeutic potential for neurolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16a1aeee9f22112f992b6a76d731b530
https://doi.org/10.1161/str.54.suppl_1.wmp110
https://doi.org/10.1161/str.54.suppl_1.wmp110
Autor:
Jinah Han, Charles-Félix Calvo, Tae Hyuk Kang, Kasey L. Baker, June-Hee Park, Carlos Parras, Marine Levittas, Ulrick Birba, Laurence Pibouin-Fragner, Pascal Fragner, Kaya Bilguvar, Ronald S. Duman, Harri Nurmi, Kari Alitalo, Anne C. Eichmann, Jean-Léon Thomas
Publikováno v:
Cell Reports, Vol 10, Iss 7, Pp 1158-1172 (2015)
Neural stem cells (NSCs) continuously produce new neurons within the adult mammalian hippocampus. NSCs are typically quiescent but activated to self-renew or differentiate into neural progenitor cells. The molecular mechanisms of NSC activation remai
Externí odkaz:
https://doaj.org/article/315ad1d0e24c4d85a80af7b8470c6a50
Autor:
Christelle Damon-Soubeyrand, Antonino Bongiovanni, Areski Chorfa, Chantal Goubely, Nelly Pirot, Luc Pardanaud, Laurence Pibouin-Fragner, Caroline Vachias, Stéphanie Bravard, Rachel Guiton, Jean-Léon Thomas, Fabrice Saez, Ayhan Kocer, Meryem Tardivel, Joël R. Drevet, Joelle Henry-Berger
Long considered an accessory tubule of the male reproductive system, the epididymis is proving to be a key determinant of male fertility. In addition to its secretory role in ensuring functional maturation and survival of spermatozoa, the epididymis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05174a2d93517ca9b493a515817c9eb8
https://doi.org/10.1101/2022.08.26.505406
https://doi.org/10.1101/2022.08.26.505406
Publikováno v:
Medecine sciences : M/S. 35(1)
The considerable metabolic activity of the central nervous system (CNS) requires an efficient system of tissue drainage and detoxification. The CNS is however devoid of lymphatic vessels, a vasculature ensuring interstitial fluid drainage and immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4c053f84f06ba2e4ffceee3a2b0fe5d1
https://pubmed.ncbi.nlm.nih.gov/30672459
https://pubmed.ncbi.nlm.nih.gov/30672459
Autor:
Sowmya, Sekizar, Abdelkrim, Mannioui, Loris, Azoyan, Catherine, Colin, Jean-Léon, Thomas, David, Du Pasquier, Michel, Mallat, Bernard, Zalc
Publikováno v:
Developmental neuroscience. 37(3)
We have generated a Xenopus laevis transgenic line, MBP-GFP-NTR, allowing conditional ablation of myelin-forming oligodendrocytes. In this transgenic line the transgene is driven by the proximal portion of the myelin basic protein regulatory sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b08fe103090a7b2027e3402498d2071a
https://pubmed.ncbi.nlm.nih.gov/25896276
https://pubmed.ncbi.nlm.nih.gov/25896276
Autor:
Jean-Léon Thomas
Publikováno v:
The FASEB Journal. 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b906a64fa27b48f7d31f7dee9b7175d0
https://doi.org/10.1096/fasebj.21.5.a197-a
https://doi.org/10.1096/fasebj.21.5.a197-a
Publikováno v:
Journal of cell science. 107
Lately, we have identified two polypeptides of 92–94 kDa (GRL1) and 45–60 kDa (GRL2), expressed in cytoplasmic granules of chicken granulocytes and thrombocytes. Here, we report that GRL1 and GRL2 are widely distributed in all exocrine and severa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be167f09b9615da5c251beb98b71fdb
https://pubmed.ncbi.nlm.nih.gov/7929636
https://pubmed.ncbi.nlm.nih.gov/7929636
Autor:
Jean-Léon Thomas, Catherine Corbel
Publikováno v:
Developmental and comparative immunology. 14(4)
In this article, we describe a-chicken T helper-activated cell line, III-C5, which is non-antigen-specific but IL-2-dependent. By virtue of its absolute requirement for IL-2, the III-C5 cell line is a useful tool for quantifying IL-2 production by an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100ee28d505fb3026e1857e83f5e537f
https://pubmed.ncbi.nlm.nih.gov/2150822
https://pubmed.ncbi.nlm.nih.gov/2150822
Publikováno v:
Europe PubMed Central
We have identified a glycoprotein (BEN) of 95 –100 ×103Mr using a monoclonal antibody. This protein is transiently expressed at the cell surface of the peripherally projecting neurons, i.e. motoneurons of the spinal cord and cranial nuclei, sensor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d540ee7e8efd3d68f268f3338f82da17
http://europepmc.org/abstract/med/2226198
http://europepmc.org/abstract/med/2226198