Zobrazeno 1 - 10
of 289
pro vyhledávání: '"Jean-Jacques Martin"'
Autor:
Stefanie Smolders, Stéphanie Philtjens, David Crosiers, Anne Sieben, Elisabeth Hens, Bavo Heeman, Sara Van Mossevelde, Philippe Pals, Bob Asselbergh, Roberto Dos Santos Dias, Yannick Vermeiren, Rik Vandenberghe, Sebastiaan Engelborghs, Peter Paul De Deyn, Jean-Jacques Martin, Patrick Cras, Wim Annaert, Christine Van Broeckhoven, BELNEU consortium
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-15 (2021)
Abstract Dementia with Lewy bodies (DLB) and Parkinson’s disease (PD) are clinically, pathologically and etiologically disorders embedded in the Lewy body disease (LBD) continuum, characterized by neuronal α-synuclein pathology. Rare homozygous an
Externí odkaz:
https://doaj.org/article/0fced290715347dcbcc51313cf18c4b6
Autor:
Federica Perrone, Maria Bjerke, Elisabeth Hens, Anne Sieben, Maarten Timmers, Arne De Roeck, Rik Vandenberghe, Kristel Sleegers, Jean-Jacques Martin, Peter P. De Deyn, Sebastiaan Engelborghs, Julie van der Zee, Christine Van Broeckhoven, Rita Cacace, on behalf of the BELNEU Consortium
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2020)
Abstract Background Alzheimer’s disease (AD) mutations in amyloid precursor protein (APP) and presenilins (PSENs) could potentially lead to the production of longer amyloidogenic Aβ peptides. Amongst these, Aβ1–43 is more prone to aggregation a
Externí odkaz:
https://doaj.org/article/3a66eaa6876e44d293dc52f63c72776e
Autor:
Joery Goossens, Maria Bjerke, Sara Van Mossevelde, Tobi Van den Bossche, Johan Goeman, Bart De Vil, Anne Sieben, Jean-Jacques Martin, Patrick Cras, Peter Paul De Deyn, Christine Van Broeckhoven, Julie van der Zee, Sebastiaan Engelborghs
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-10 (2018)
Abstract Background We explored the diagnostic performance of cerebrospinal fluid (CSF) biomarkers in allowing differentiation between frontotemporal lobar degeneration (FTLD) and Alzheimer’s disease (AD), as well as between FTLD pathological subty
Externí odkaz:
https://doaj.org/article/f8f4e71637f14a918acbcd4e30b0dd02
Autor:
Anne Sieben, Sara Van Mossevelde, Eline Wauters, Sebastiaan Engelborghs, Julie van der Zee, Tim Van Langenhove, Patrick Santens, Marleen Praet, Paul Boon, Marijke Miatton, Sofie Van Hoecke, Mathieu Vandenbulcke, Rik Vandenberghe, Patrick Cras, Marc Cruts, Peter Paul De Deyn, Christine Van Broeckhoven, Jean-Jacques Martin
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-13 (2018)
Abstract Background In this paper, we describe the clinical and neuropathological findings of nine members of the Belgian progranulin gene (GRN) founder family. In this family, the loss-of-function mutation IVS1 + 5G > C was identified in 2006. In 20
Externí odkaz:
https://doaj.org/article/62394803736045fe8e421489ba4a07da
Autor:
Alain D. Dekker, Yannick Vermeiren, Maria Carmona‐Iragui, Bessy Benejam, Laura Videla, Ellen Gelpi, Tony Aerts, Debby Van Dam, Susana Fernández, Alberto Lleó, Sebastian Videla, Anne Sieben, Jean‐Jacques Martin, Netherlands Brain Bank, Rafael Blesa, Juan Fortea, Peter P. De Deyn
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 10, Iss 1, Pp 99-111 (2018)
Abstract Introduction People with Down syndrome (DS) are at high risk for Alzheimer's disease (AD). Defects in monoamine neurotransmitter systems are implicated in DS and AD but have not been comprehensively studied in DS. Methods Noradrenaline, adre
Externí odkaz:
https://doaj.org/article/d4ab168ebe3f432eb3c4e7d2baaea7d3
Autor:
Joery Goossens, Maria Bjerke, Hanne Struyfs, Ellis Niemantsverdriet, Charisse Somers, Tobi Van den Bossche, Sara Van Mossevelde, Bart De Vil, Anne Sieben, Jean-Jacques Martin, Patrick Cras, Johan Goeman, Peter Paul De Deyn, Christine Van Broeckhoven, Julie van der Zee, Sebastiaan Engelborghs
Publikováno v:
Alzheimer’s Research & Therapy, Vol 9, Iss 1, Pp 1-7 (2017)
Abstract Background The Alzheimer’s disease (AD) cerebrospinal fluid (CSF) biomarkers Aβ1–42, t-tau, and p-tau181 overlap with other diseases. New tau modifications or epitopes, such as the non-phosphorylated tau fraction (p-taurel), may improve
Externí odkaz:
https://doaj.org/article/739dc84822e24a58a0682c69e1703657
Autor:
Lukas J. Schnitzler, Tobias Schreckenbach, Aleksandra Nadaj-Pakleza, Werner Stenzel, Elisabeth J. Rushing, Philip Van Damme, Andreas Ferbert, Susanne Petri, Christian Hartmann, Antje Bornemann, Andreas Meisel, Jens A. Petersen, Thomas Tousseyn, Dietmar R. Thal, Jens Reimann, Peter De Jonghe, Jean-Jacques Martin, Peter Y. Van den Bergh, Jörg B. Schulz, Joachim Weis, Kristl G. Claeys
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 12, Iss 1, Pp 1-12 (2017)
Abstract Background Sporadic late-onset nemaline myopathy (SLONM) is a rare, late-onset muscle disorder, characterized by the presence of nemaline rods in muscle fibers. Phenotypic characterization in a large cohort and a comprehensive overview of SL
Externí odkaz:
https://doaj.org/article/d683de3e2eeb4e0290c805d869e0301b
Autor:
Jorne Laton, Jeroen Van Schependom, Joery Goossens, Wietse Wiels, Anne Sieben, Peter Paul De Deyn, Johan Goeman, Johannes Streffer, Julie van der Zee, Jean-Jacques Martin, Christine Van Broeckhoven, Maarten De Vos, Maria Bjerke, Guy Nagels, Sebastiaan Engelborghs
Publikováno v:
Journal of Alzheimer's disease
Journal of Alzheimer's disease : JAD, 90(4), 1739-1747. IOS Press
Journal of Alzheimer's disease : JAD, 90(4), 1739-1747. IOS Press
BACKGROUND: Distinguishing between Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD) results in poor diagnostic accuracy. OBJECTIVE: To investigate the utility of electroencephalography (EEG)-based biomarkers in comparison and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6093ef20e4b625800927b53a1bad36
https://lirias.kuleuven.be/handle/20.500.12942/712826
https://lirias.kuleuven.be/handle/20.500.12942/712826
Autor:
Charlotte E. Teunissen, Jean-Jacques Martin, Maarten Timmers, Patrick Cras, Yannick Vermeiren, Naomi De Roeck, Anne Sieben, Maria Bjerke, Charisse Somers, Christine Van Broeckhoven, Bart De Vil, Peter Paul De Deyn, Sebastiaan Engelborghs, Eline A.J. Willemse
Publikováno v:
Willemse, E A J, Sieben, A, Somers, C, Vermeiren, Y, de Roeck, N, Timmers, M, van Broeckhoven, C, de Vil, B, Cras, P, de Deyn, P P, Martin, J-J, Teunissen, C E, Engelborghs, S & Bjerke, M 2021, ' Neurogranin as biomarker in CSF is non-specific to Alzheimer's disease dementia ', Neurobiology of Aging, vol. 108, pp. 99-109 . https://doi.org/10.1016/j.neurobiolaging.2021.08.002
Neurobiology of aging
Neurobiology of Aging, 108, 99-109. Elsevier Inc.
Neurobiology of aging 108 (2021)
Neurobiology of aging, 108, 99-109
Neurobiology of aging
Neurobiology of Aging, 108, 99-109. Elsevier Inc.
Neurobiology of aging 108 (2021)
Neurobiology of aging, 108, 99-109
We aimed to evaluate the specificity of neurogranin (Ng) for Alzheimer's disease (AD) in a dementia cohort. Cerebrospinal fluid (CSF) Ng was measured (ELISA) in two independent cohorts: (1) clinical (n = 116; age 72±11 years): AD, non-AD (+high T-ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a368df0a6a0f9d59c5492515949b994
https://research.vumc.nl/en/publications/7401124c-d959-45c0-a55b-156eb7648d89
https://research.vumc.nl/en/publications/7401124c-d959-45c0-a55b-156eb7648d89
Autor:
Robrecht Raedt, Peter Paul De Deyn, Dimitri Vanhauwaert, Tim Van Langenhove, Céline Cousaert, Paul Boon, Anne Sieben, Katia De Meulemeester, Helena Gossye, Maria Bjerke, Marleen Praet, Jean-Jacques Martin, Patrick Santens, Sebastiaan Engelborghs, Christine Van Broeckhoven, Ken R. Bracke, Yannick Vermeiren
Publikováno v:
Journal of Neuropathology and Experimental Neurology, 80(4), 313-324
Journal of Neuropathology and Experimental Neurology 80 (2021) 4
Journal of neuropathology and experimental neurology, 80(4), 313-324. Oxford University Press
Journal of neuropathology and experimental neurology
Journal of Neuropathology and Experimental Neurology 80 (2021) 4
Journal of neuropathology and experimental neurology, 80(4), 313-324. Oxford University Press
Journal of neuropathology and experimental neurology
Hippocampal sclerosis (HS) is a common neuropathological finding and has been associated with advanced age, TDP-43 proteinopathy, and cerebrovascular pathology. We analyzed neuropathological data of an autopsy cohort of early-onset frontotemporal dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5c836ffba3f34c0c8fd57fee91ba617
https://biblio.vub.ac.be/vubir/(fbf56d1f-6e71-472f-982f-80c5cec9d5e0).html
https://biblio.vub.ac.be/vubir/(fbf56d1f-6e71-472f-982f-80c5cec9d5e0).html