Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jean-Jacques Curgy"'
Publikováno v:
International Journal of Peptide and Protein Research. 39:300-307
Total mRNA were extracted from brain of Nereis diversicolor (Annelida, Polychaeta) and were translated in vitro or in ovo. The newly synthesized polypeptides were analyzed through electrophoresis of immunoprecipitated products or the Western blotting
Autor:
Jean Coll, Eric Adriaenssens, Nathalie Spruyt, Guy Cathala, Anthony Daccache, Thierry Forné, Thierry Dugimont, Céline Genton, Hubert Hondermarck, Jean-Jacques Curgy, Nathalie Berteaux, Nathalie Aptel
Publikováno v:
Molecular and Cellular Biology. 28:6731-6745
The H19/IGFf2 locus belongs to a large imprinted domain located on human chromosome 11p15.5 (homologue to mouse distal chromosome 7). The H19 gene is expressed from the maternal allele, while IGF2 is paternally expressed. Natural antisense transcript
Autor:
Thierry Dugimont, Didier Monté, Hubert Hondermarck, Eric Adriaenssens, Jean Coll, Jean-Jacques Curgy, Séverine Lottin, Nathalie Berteaux, Brigitte Quatannens, Sébastien Pinte
Publikováno v:
Journal of Biological Chemistry. 280:29625-29636
The imprinted H19 gene has riboregulatory functions. We show here that H19 transcription is up-regulated during the S-phase of growth-stimulated cells and that the H19 promoter is activated by E2F1 in breast cancer cells. H19 repression by pRb and E2
Autor:
Claire Montpellier, Thierry Dupressoir, Nathalie Berteaux, Jean Coll, Thierry Dugimont, Eric Adriaenssens, Jean Jacques Curgy, Séverine Lottin
Publikováno v:
Carcinogenesis. 23:1885-1895
The maternally expressed H19 gene is transcribed as an untranslated RNA that serves as a riboregulator. We have previously reported that this transcript accumulates in epithelial cells in approximately 10% of breast cancers. To gain further insight o
Autor:
Nathalie Berteaux, Eric Adriaenssens, Jean-Philippe Peyrat, Jean-Jacques Curgy, Véronique Fafeur, William Fauquette, Louis Hornez, Jean Coll, Xuefen Le Bourhis, Thierry Dugimont, Hubert Hondermarck, Séverine Lottin
Publikováno v:
Experimental Cell Research. 275:215-229
The H19 gene is an imprinted gene expressed from the maternal allele. It is known to function as an RNA molecule. We previously reported that in breast adenocarcinoma, H19 is often overexpressed in stromal cells and preferentially located at the epit
Autor:
Morad Roudbaraki, Jean-Jacques Curgy, Eric Adriaenssens, Jérôme Lemoine, Thierry Dugimont, Séverine Lottin, Xavier Czeszak, Jean Coll, Hubert Hondermarck, Anne-Sophie Vercoutter-Edouart
Publikováno v:
Oncogene. 21:1625-1631
Classically, the functional product of coding genes is a protein whose synthesis is directed by an mRNA-template. However, in the last few years several genes yielding an mRNA-like non-coding RNA as a functional product have been identified. In most
Autor:
W Fauquette, J P Dupouy, Jean-Jacques Curgy, Jean Coll, Thierry Dugimont, B Boilly, Séverine Lottin, Eric Adriaenssens
Publikováno v:
Oncogene. 18:4460-4473
H19 is an imprinted and developmentally regulated gene whose product remains apparently untranslated. In a previous study on breast adenocarcinomas, we reported that overexpression of the H19 gene was significantly correlated with the presence of ste
Autor:
Alice Delobelle, Jean-Jacques Curgy, Alain Leprêtre, Séverine Lottin, Fatima Bouali, Domitille Bolle, Jean Coll, Thierry Dugimont, Eric Adriaenssens, Lionel Dumont
Publikováno v:
The American Journal of Pathology. 153:1597-1607
In a previous study we described the expression of the H19 gene by in situ hybridization (ISH) in normal breast and in benign or malignant breast tumors (Dugimont T, Curgy JJ, Wernert N, Delobelle A. Raes MB, Joubel A, Stehelin D, Coll J: Biol Cell 1
Autor:
Claire Montpellier, Christian Lagrou, Jean-Jacques Curgy, Violetta Iotsova, Lionel Dumont, Jean Coll, Séverine Lottin, Eric Adriaenssens, Dominique Stehelin, Thierry Dugimont
Publikováno v:
Oncogene. 16:2395-2401
The developmentally regulated H19 gene displays several remarkable properties: expression of an apparently non-translated mRNA, genomic imprinting (maternal allele only expressed), relaxation of the imprinting and/or epigenetic lesions demonstrated i
Autor:
Anne Delobelle, Anita Joubel, Jean Coll, Thierry Dugimont, Jean-Jacques Curgy, Marie-Berthe Raes, Nicolas Wernert, Dominique Stehelin
Publikováno v:
Biology of the Cell. 85:117-124
Summary In a previous work, we have isolated the human H19 gene and shown accumulation of transcripts in various human tumors including breast carcinomas ( Douc-Rasy et al (1993) Int J Oncol 2, 753–758). Questions arose, after Northern blot results