Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Jean-Jacques Helesbeux"'
Autor:
Julia Courtial, Jean-Jacques Helesbeux, Hugo Oudart, Sophie Aligon, Muriel Bahut, Bruno Hamon, Guillaume N’Guyen, Sandrine Pigné, Ahmed G. Hussain, Claire Pascouau, Nelly Bataillé-Simoneau, Jérôme Collemare, Romain Berruyer, Pascal Poupard
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-20 (2022)
Abstract Alternaria dauci is a Dothideomycete fungus, causal agent of carrot leaf blight. As a member of the Alternaria genus, known to produce a lot of secondary metabolite toxins, A. dauci is also supposed to synthetize host specific and non-host s
Externí odkaz:
https://doaj.org/article/b9bdf50383b14d2285a56659ac99ccfe
Autor:
Ida Cerqua, Konstantin Neukirch, Michela Terlizzi, Elisabetta Granato, Elisabetta Caiazzo, Carla Cicala, Armando Ialenti, Raffaele Capasso, Oliver Werz, Rosalinda Sorrentino, Denis Seraphin, Jean-Jacques Helesbeux, Giuseppe Cirino, Andreas Koeberle, Fiorentina Roviezzo, Antonietta Rossi
Publikováno v:
Pharmacological Research, Vol 181, Iss , Pp 106250- (2022)
Benefits for vitamin E intake in diseases with inflammatory components have been described and related in part, to endogenously formed metabolites (long-chain metabolites, LCM). Here, we have evaluated the role of LCM in relieving asthma features. To
Externí odkaz:
https://doaj.org/article/cde91b43354b4b5a972cc24aaddca0c7
Autor:
Niamh M. O’Boyle, Jean-Jacques Helesbeux, Mary J. Meegan, Astrid Sasse, Elizabeth O’Shaughnessy, Alina Qaisar, Aoife Clancy, Florence McCarthy, Pascal Marchand
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 432 (2023)
The Group for the Promotion of Pharmaceutical Chemistry in Academia (GP2A) held their 30th annual conference in August 2022 in Trinity College Dublin, Ireland. There were 9 keynote presentations, 10 early career researcher presentations and 41 poster
Externí odkaz:
https://doaj.org/article/2ee297a77f5e499aa47fe752cf8860d2
Autor:
Marie-Louisa Ramaroson, Claude Koutouan, Jean-Jacques Helesbeux, Valérie Le Clerc, Latifa Hamama, Emmanuel Geoffriau, Mathilde Briard
Publikováno v:
Molecules, Vol 27, Iss 23, p 8371 (2022)
Phenylpropanoids and flavonoids are specialized metabolites frequently reported as involved in plant defense to biotic or abiotic stresses. Their biosynthetic accumulation may be constitutive and/or induced in response to external stimuli. They may p
Externí odkaz:
https://doaj.org/article/84a3b0852d424df5bfa69ffae347d1ce
Autor:
Gabriele Möller, Veronika Temml, Antonio Cala Peralta, Océane Gruet, Pascal Richomme, Denis Séraphin, Guillaume Viault, Luisa Kraus, Petra Huber-Cantonati, Elisabeth Schopfhauser, Johanna Pachmayr, Janina Tokarz, Daniela Schuster, Jean-Jacques Helesbeux, Kenneth Allen Dyar
Publikováno v:
Metabolites, Vol 12, Iss 2, p 99 (2022)
Naturally occurring substances are valuable resources for drug development. In this respect, chalcones are known to be antiproliferative agents against prostate cancer cell lines through various mechanisms or targets. Based on the literature and prel
Externí odkaz:
https://doaj.org/article/2ab68851bb2c41d1830b279e836dcadf
Autor:
Helmut Pein, Alexia Ville, Simona Pace, Veronika Temml, Ulrike Garscha, Martin Raasch, Khaled Alsabil, Guillaume Viault, Chau-Phi Dinh, David Guilet, Fabiana Troisi, Konstantin Neukirch, Stefanie König, Rosella Bilancia, Birgit Waltenberger, Hermann Stuppner, Maria Wallert, Stefan Lorkowski, Christina Weinigel, Silke Rummler, Marc Birringer, Fiorentina Roviezzo, Lidia Sautebin, Jean-Jacques Helesbeux, Denis Séraphin, Alexander S. Mosig, Daniela Schuster, Antonietta Rossi, Pascal Richomme, Oliver Werz, Andreas Koeberle
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Vitamin E metabolites are proposed to have signalling capacity, but how they may regulate immune responses is still unclear. Here the authors show that a vitamin E metabolite, α-T-13′-COOH, can inhibit 5-lipoxygenase and thereby suppress the synth
Externí odkaz:
https://doaj.org/article/8f5b1e43017943509f14b4b68fe07ec5
Autor:
Jean-Jacques Helesbeux, Laura Carro, Florence O. McCarthy, Vânia M. Moreira, Francesca Giuntini, Niamh O’Boyle, Susan E. Matthews, Gülşah Bayraktar, Samuel Bertrand, Christophe Rochais, Pascal Marchand
Publikováno v:
Pharmaceuticals, Vol 14, Iss 12, p 1278 (2021)
The 29th Annual GP2A (Group for the Promotion of Pharmaceutical chemistry in Academia) Conference was a virtual event this year due to the COVID-19 pandemic and spanned three days from Wednesday 25 to Friday 27 August 2021. The meeting brought togeth
Externí odkaz:
https://doaj.org/article/186f3eb6d769421e89d8c8a6c442f19c
Autor:
Julia Courtial, Latifa Hamama, Jean-Jacques Helesbeux, Mickaël Lecomte, Yann Renaux, Esteban Guichard, Linda Voisine, Claire Yovanopoulos, Bruno Hamon, Laurent Ogé, Pascal Richomme, Mathilde Briard, Tristan Boureau, Séverine Gagné, Pascal Poupard, Romain Berruyer
Publikováno v:
Frontiers in Plant Science, Vol 9 (2018)
Qualitative plant resistance mechanisms and pathogen virulence have been extensively studied since the formulation of the gene-for-gene hypothesis. The mechanisms involved in the quantitative traits of aggressiveness and plant partial resistance are
Externí odkaz:
https://doaj.org/article/a989e3dc681543daa5384270e2a1f9e0
Autor:
Rodolphe Perrot, Jean-Jacques Helesbeux, Denis Séraphin, Marie Kempf, Pascal Richomme, Khaled Alsabil, Guillaume Viault, Alexia Ville
Publikováno v:
ChemMedChem
ChemMedChem, Wiley-VCH Verlag, 2021, 16 (5), pp.881-890. ⟨10.1002/cmdc.202000792⟩
ChemMedChem, Wiley-VCH Verlag, 2021, 16 (5), pp.881-890. ⟨10.1002/cmdc.202000792⟩
New 5-substituted vitamin E derivatives were semisynthesized, and their antibacterial activity against human Gram-positive and Gram-negative pathogens was evaluated. Several vitamin E analogues were active against methicillin-resistant Staphylococcus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490659c4c8c7aed149cab7177434bb72
https://doi.org/10.1002/cmdc.202000792
https://doi.org/10.1002/cmdc.202000792
Autor:
Ida Cerqua, Konstantin Neukirch, Michela Terlizzi, Elisabetta Granato, Elisabetta Caiazzo, Carla Cicala, Armando Ialenti, Raffaele Capasso, Oliver Werz, Rosalinda Sorrentino, Denis Seraphin, Jean-Jacques Helesbeux, Giuseppe Cirino, Andreas Koeberle, Fiorentina Roviezzo, Antonietta Rossi
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06403ade985c59af6bcb4093792894db
https://doi.org/10.2139/ssrn.4079610
https://doi.org/10.2139/ssrn.4079610