Ruxolitinib for Glucocorticoid-Refractory Acute Graft-versus-Host Disease

Autor: Zeiser, R., von Bubnoff, N., Butler, J., Mohty, M., Niederwieser, D., Or, R., Szer, J., Wagner, E. M., Zuckerman, T., Mahuzier, B., Xu, J., Wilke, C., Gandhi, K. K., Socie, G, Sung-Soo, Yoon, Chulwon, Jung, Tobias, Gedde-Dahl, Marwan, Shaheen, Jose Antonio Perez Simon, Jose Valentin Garcia Gutierrez, Jaime Sanz Caballer, Rafael Duarte Palomino, David Valcarcel Ferreiras, Cristina Diaz de Heredia Rubio, Kwon, Mi, Maria Del Carmen Martinez Munoz, Soledad, Gonzalez, Matilde Rodriguez Ruiz, Inmaculada Heras Fernando, Maria Pascual Cascon, Ana Sastre Urgelles, Marta Gonzalez Vicent, Jose Maria Fernandez Navarro, Yvonne, Björk, Kristina, Carlson, Jih-Luh, Tang, Su-Peng, Yeh, Ronjon, Chakraverty, Robert, Wynn, Lajos, Floro, Brian Thomas Kornblit, Jason, Butler, David, Ritchie, John, Kwan, Jacqueline, Fleming, Duncan, Purtill, Georg, Hopfinger, Hildegard, Greinix, Johannes, Clausen, Dennis, Kim, Natasha, Kekre, Imran, Ahmad, Brian, Leber, Andrew, Daly, Gizelle, Popradi, Jennifer, White, Mohamed, Elemary, Gerard, Socie, Valérie, Coiteux, Patrice, Chevallier, Claude-Eric, Bulabois, Helene, Labussiere-Wallet, Mohamad, Mohty, Pierre-Simon, Rohrlich, Edouard, Forcade, Fabrice, Larosa, Sylvie, Francois, Stephanie N'Guyen Quoc, Marie-Therese, Rubio, Jean-Hughes, Dalle, Marie, Ouachee-Chardin, Benedicte, Bruno, Anne, Huynh, Nathalie, Fegueux, Jerome, Cornillon, Pascal, Turlure, Nikolas von Bubnoff, Georg-Nikolaus, Franke, Friedrich, Stoelzel, Matthias, Eder, Arne, Brecht, Nicolaus, Kroeger, Nina-Kristin, Steckel, Eva, Wagner, Guido, Kobbe, Wolfgang, Bethge, Matthias, Stelljes, Donald, Bunjes, Igor, Blau, Ingo, Mueller, Stefan, Klein, Christoph, Schmid, Lena, Oevermann, Herrad, Baurmann, Inken, Hilgendorf, Klaus Daniel Stachel, Yok-Lam, Kwong, Ron, Ram, Batya, Avni, Moshe, Yeshurun, Tsila, Zuckerman, Riccardo, Saccardi, Paolo, Corradini, Franco, Locatelli, Alessandro, Rambaldi, Andrea, Bacigalupo, Attilio, Olivieri, Francesca, Patriarca, Giovanni, Grillo, Francesca, Bonifazi, Edoardo, Lanino, Attilio, Rovelli, Benedetto, Bruno, Russo, Domenico, Maurizio, Musso, Marco, Zecca, Franca, Fagioli, Angelo Michele Carella, Stefania, Bregante, Roberto, Sorasio, Takanori, Teshima, Koichi, Miyamura, Kiyoshi, Ando, Hirohisa, Nakamae, Yoshinobu, Maeda, Tadakazu, Kondo, Masaya, Okada, Kazuhiko, Kakihana, Koji, Kato, Yasushi, Onishi, Kentaro, Fukushima, Shuichi, Taniguchi, Takehiko, Mori, Takayuki, Ishikawa, Yoshihiro, Inamoto, Kuball, J, A Lindemans, C, Jan, Vydra, Achilleas, Anagnostopoulos, Zubeyde, Ozkurt, Zafer, Gulbas, Seckin, Cagirgan, Sinem Civriz Bozdag, Penka, Ganeva, Dobrin, Konstantinov, Kazimierz, Halaburda, Jan, Zaucha, Gergely KrivÃ, N, Isabelina, Ferreira, Joao Forjaz de Lacerda, Alexey, Maschan, Elena, Parovichnikova

Acute graft-versus-host disease (GVHD) remains a major limitation of allogeneic stem-cell transplantation; not all patients have a response to standard glucocorticoid treatment. In a phase 2 trial, ruxolitinib, a selective Janus kinase (JAK1 and JAK2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b695b267a2a6439599dcd2674f979a
http://hdl.handle.net/11379/531211

p16INK4a immunocytochemical analysis is an independent prognostic factor in childhood acute lymphoblastic leukemia

Autor: Françoise Mazingue, Martine Fournier, Brigitte Nelken, Jean-Luc Laï, Bruno Quesnel, Pierre Fenaux, Jean Hughes Dalle, Francis Bauters

Publikováno v: Blood. 99:2620-2623

We investigated the prognostic value of p16INK4aimmunocytochemistry (ICC) analysis in 126 cases of newly diagnosed childhood acute lymphoblastic leukemia (ALL). The incidence of negative p16INK4a ICC was 38.1% and was more frequent in T-lineage ALL.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f4164fa0a09e4de6ec0bc89b185f74
https://doi.org/10.1182/blood.v99.7.2620

Acute megakaryoblastic leukemia with der(7)t(5;7)(q11;p11∼p12) associated with Down syndrome: a fourth case report

Autor: Catherine Roche-Lestienne, Steven Richebourg, Jean-Luc Laï, Blandine Roquefeuil, Joris Andrieux, Nicole Dastugue, Jean-Hughes Dalle

Publikováno v: Cancer Genetics and Cytogenetics. 169:184-186

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9b4ff8b4c6516678c9a75f09629ef068
https://doi.org/10.1016/j.cancergencyto.2006.03.006

Long-Term Outcomes of Hematopoietic Stem Cell Transplantation for Severe Treatment-Resistant Autoimmune Cytopenia in Children

Autor: Brenda Gibson, Jean Hughes Dalle, Paul Veys, Christina Peters, Chiara Messina, Marco Rabusin, Colin G. Steward, Paolo Bartolomeo, Igor Lisukov, Valérie Mialou, Dominique Farge, Marleen Renard, John A. Snowden, Giorgio Dini, Nagua Giurici, Manuela Badoglio, Luca Ronfani, Arturo Iriondo, Catharina Dhooge, Herbert Juergens, Maria Gonzalez-Vicent, Pierre Quartier, Riccardo Saccardi, Christian Urban

Publikováno v: Biology of Blood and Marrow Transplantation. (4):666-669

We analyzed the long-term outcomes of pediatric patients registered in the European Group for Blood and Marrow Transplantation database who underwent hematopoietic stem cell transplantation (HSCT) for severe treatment refractory autoimmune cytopenia.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce7d5f5c6db3a7fb7a1c137c74b33c83