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pro vyhledávání: '"Jean-Guy Lehoux"'
Autor:
Jean-Guy Lehoux
Publikováno v:
Frontiers in Neuroscience, Vol 10 (2016)
Objective: Review the impact of StAR (STARD1) mutations on steroidogenesis and fertility in LCAH patients. Examine the endocrine mechanisms underlying the pathology of the disorder and the appropriate therapy for promoting fertility and pregnancies.D
Externí odkaz:
https://doaj.org/article/ac4156e626ed4dc19964a0161b3e7e4e
Autor:
Danny Létourneau, Aurélien Lorin, Andrée Lefebvre, Vincent Frappier, Francis Gaudreault, Rafael Najmanovich, Pierre Lavigne, Jean-Guy LeHoux
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 12, Pp 2677-2689 (2012)
Steroidogenic acute regulatory-related lipid transfer (START) domain proteins are involved in the nonvesicular intracellular transport of lipids and sterols. The STARD1 (STARD1 and STARD3) and STARD4 subfamilies (STARD4–6) have an internal cavity l
Externí odkaz:
https://doaj.org/article/3e20e8ba00a143d4839f5733c94465a5
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 10, Pp 1552-1561 (2000)
The incidence of atherosclerosis and related diseases increases with age. The aging process may enhance lipoprotein modification, which leads to an increase in the susceptibility of low density lipoprotein (LDL) and high density lipoprotein (HDL) to
Externí odkaz:
https://doaj.org/article/3ad130d17e914d579f7934533b83335e
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1949
The use of direct calorimetric methods such as isothermal titration calorimetry for measuring the affinity and specificity of protein-ligand interactions requires large amounts of proteins and ligands. When material is scarce and/or in the absence of
Publikováno v:
Methods in Molecular Biology ISBN: 9781493991358
The use of direct calorimetric methods such as isothermal titration calorimetry for measuring the affinity and specificity of protein-ligand interactions requires large amounts of proteins and ligands. When material is scarce and/or in the absence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6892b4c08058214a39ad91ca9020a3de
https://doi.org/10.1007/978-1-4939-9136-5_20
https://doi.org/10.1007/978-1-4939-9136-5_20
Publikováno v:
Molecular and Cellular Endocrinology. 408:53-61
Steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domain proteins display diverse expression patterns and cellular localisations. They bind a large variety of lipids and sterols and are involved in lipid metabolism, lipid t
Autor:
Donald Poirier, René Maltais, Danny Létourneau, Martin Perreault, Stéphane Gobeil, Jean-Guy Lehoux, Lucie Carolle Kenmogne
Publikováno v:
Pharmacological research. 128
The aminosteroid derivative RM-133 is an effective anticancer molecule for which proof of concept has been achieved in several mouse xenograph models (HL-60, MCF-7, PANC-1 and OVCAR-3). To promote this new family of molecules toward a clinical phase
Publikováno v:
Frontiers in Neuroscience
Frontiers in Neuroscience, Vol 10 (2016)
Frontiers in Neuroscience, Vol 10 (2016)
Objective: Review the impact of StAR (STARD1) mutations on steroidogenesis and fertility in LCAH patients. Examine the endocrine mechanisms underlying the pathology of the disorder and the appropriate therapy for promoting fertility and pregnancies.
Autor:
Danny Létourneau, Aurélien Lorin, Pierre Lavigne, Jean-Guy Lehoux, Jérôme Cabana, Andrée Lefebvre
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1831:1589-1599
STARD5 is a member of the STARD4 sub-family of START domain containing proteins specialized in the non-vesicular transport of lipids and sterols. We recently reported that STARD5 binds primary bile acids. Herein, we report on the biophysical and stru
Autor:
Jean-Guy Lehoux, Vincent Frappier, Pierre Lavigne, Aurélien Lorin, Andrée Lefebvre, Rafael Najmanovich, Francis Gaudreault, Danny Létourneau
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 12, Pp 2677-2689 (2012)
Steroidogenic acute regulatory-related lipid transfer (START) domain proteins are involved in the nonvesicular intracellular transport of lipids and sterols. The STARD1 (STARD1 and STARD3) and STARD4 subfamilies (STARD4-6) have an internal cavity lar