Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Jean-Gabriel Judde"'
Autor:
Tala Tayoun, Vincent Faugeroux, Marianne Oulhen, Olivier Déas, Judith Michels, Laura Brulle-Soumare, Stefano Cairo, Jean-Yves Scoazec, Virginie Marty, Agathe Aberlenc, David Planchard, Jordi Remon, Santiago Ponce, Benjamin Besse, Patricia L. Kannouche, Jean-Gabriel Judde, Patrycja Pawlikowska, Françoise Farace
Publikováno v:
JCI Insight, Vol 7, Iss 11 (2022)
DNA damage and genomic instability contribute to non–small cell lung cancer (NSCLC) etiology and progression. However, their therapeutic exploitation is disappointing. CTC-derived explants (CDX) offer systems for mechanistic investigation of CTC me
Externí odkaz:
https://doaj.org/article/e641159387994f2a91ffabd1b17d0b73
Autor:
Vincent Faugeroux, Emma Pailler, Marianne Oulhen, Olivier Deas, Laura Brulle-Soumare, Céline Hervieu, Virginie Marty, Kamelia Alexandrova, Kiki C. Andree, Nikolas H. Stoecklein, Dominique Tramalloni, Stefano Cairo, Maud NgoCamus, Claudio Nicotra, Leon W. M. M. Terstappen, Nicolo Manaresi, Valérie Lapierre, Karim Fizazi, Jean-Yves Scoazec, Yohann Loriot, Jean-Gabriel Judde, Françoise Farace
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Better tumor models are needed for the neuroendocrine subtype of castration resistant prostate cancer (CRPC-NE). Here, the authors develop patient-derived model from circulating tumor cells of a CRPC-NE patient, and provide insights on the sequential
Externí odkaz:
https://doaj.org/article/3ccca0e5b5dc46c78df201565348528a
Autor:
Katja Eloranta, Stefano Cairo, Emmi Liljeström, Tea Soini, Antti Kyrönlahti, Jean-Gabriel Judde, David B. Wilson, Markku Heikinheimo, Marjut Pihlajoki
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background: Hepatoblastoma (HB) is the most common pediatric liver malignancy. Despite advances in chemotherapeutic regimens and surgical techniques, the survival of patients with advanced HB remains poor, underscoring the need for new therapeutic ap
Externí odkaz:
https://doaj.org/article/9cf94d15b3844ceca7251741247b569d
Autor:
Marta Castroviejo‐Bermejo, Cristina Cruz, Alba Llop‐Guevara, Sara Gutiérrez‐Enríquez, Mandy Ducy, Yasir Hussein Ibrahim, Albert Gris‐Oliver, Benedetta Pellegrino, Alejandra Bruna, Marta Guzmán, Olga Rodríguez, Judit Grueso, Sandra Bonache, Alejandro Moles‐Fernández, Guillermo Villacampa, Cristina Viaplana, Patricia Gómez, Maria Vidal, Vicente Peg, Xavier Serres‐Créixams, Graham Dellaire, Jacques Simard, Paolo Nuciforo, Isabel T Rubio, Rodrigo Dienstmann, J Carl Barrett, Carlos Caldas, José Baselga, Cristina Saura, Javier Cortés, Olivier Déas, Jos Jonkers, Jean‐Yves Masson, Stefano Cairo, Jean‐Gabriel Judde, Mark J O'Connor, Orland Díez, Judith Balmaña, Violeta Serra
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 12, Pp 1-16 (2018)
Abstract Poly(ADP‐ribose) polymerase (PARP) inhibitors (PARPi) are effective in cancers with defective homologous recombination DNA repair (HRR), including BRCA1/2‐related cancers. A test to identify additional HRR‐deficient tumors will help to
Externí odkaz:
https://doaj.org/article/338354bc305a441ba1ed0aea5e8d5f0d
Autor:
Chiara Agnoletto, Linda Minotti, Laura Brulle-Soumare, Lorenzo Pasquali, Marco Galasso, Fabio Corrà, Federica Baldassari, Jean-Gabriel Judde, Stefano Cairo, Stefano Volinia
Publikováno v:
Biomarker Research, Vol 6, Iss 1, Pp 1-9 (2018)
Abstract Background We aim to characterize the heterogeneous circulating tumour cells (CTCs) in peripheral blood, independently of physical or immunological purification, by using patient-derived xenografts (PDXs) models. CTC studies from blood gener
Externí odkaz:
https://doaj.org/article/4577d878adb24b779c1893d4915031f6
Autor:
Marie-France Poupon, Dominique Bellet, Françoise Praz, Bernard Dutrillaux, Pierre Validire, Nathalie Auger, Jean-Louis Janneau, Jean-Gabriel Judde, Patrick Saulnier, Franck Assayag, Louis-Bastien Weiswald, Sophie Richon, Marc Pocard, Virginie Dangles-Marie
Obtaining representative human colon cancer cell lines from fresh tumors is technically difficult. Using 32 tumor fragments from patients with colon cancer, the present study shows that prior xenograft leads to more efficient cell line establishment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ecabf60434f939d2b747f7296b277f6
https://doi.org/10.1158/0008-5472.c.6495419
https://doi.org/10.1158/0008-5472.c.6495419
Autor:
Marie-France Poupon, Dominique Bellet, Françoise Praz, Bernard Dutrillaux, Pierre Validire, Nathalie Auger, Jean-Louis Janneau, Jean-Gabriel Judde, Patrick Saulnier, Franck Assayag, Louis-Bastien Weiswald, Sophie Richon, Marc Pocard, Virginie Dangles-Marie
Supplementary Material and Methods from Establishment of Human Colon Cancer Cell Lines from Fresh Tumors versus Xenografts: Comparison of Success Rate and Cell Line Features
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0967cd053a2c3672268a85513450cf36
https://doi.org/10.1158/0008-5472.22367090.v1
https://doi.org/10.1158/0008-5472.22367090.v1
Autor:
Silvia Grassilli, Federica Brugnoli, Stefano Cairo, Nicoletta Bianchi, Jean-Gabriel Judde, Valeria Bertagnolo
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 6; Pages: 993
Triple negative breast cancer (TNBC) represents the most aggressive breast tumor, showing a high intrinsic variability in terms of both histopathological features and response to therapies. Blocking the Akt signaling pathway is a well-studied approac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237bf3615d656ec8e173ab14588e924d
Autor:
Delphine Nicolle, Laura Brulle-Soumare, Katell Mevel, Ludovic Bigot, Tala Tayoun, Benjamin Besse, Françoise Farace, Luc Friboulet, Didier Decaudin, Erwan Corcuff, Anaïs Joachim, Bernard Malissen, Ana Zarubica, Hervé Luche, Jean-Gabriel Judde, Olivier Deas
Publikováno v:
Cancer Research. 83:4678-4678
Lung cancer remains the first cause of cancer-related deaths worldwide, of which Non-Small Cell Lung Cancer (NSCLC) represents more than 80% of patients with advanced disease at the time of diagnosis. NSCLC is a highly heterogenous disease, and the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21d98b8a9c28a3ffbc8131ecb9bc9d02
https://doi.org/10.1158/1538-7445.am2023-4678
https://doi.org/10.1158/1538-7445.am2023-4678
Autor:
Delphine Nicolle, Aurore Gorce, Marie Tavernier, Elisabetta Marangoni, Didier Decaudin, Christophe Ginestier, Emmanuelle Charafe-Jaufret, Judith Passildas, Nina Robin, Robert Clarke, Erwan Corcuff, Anaïs Joachim, Bernard Malissen, Ana Zarubica, Hervé Luche, Jean-Gabriel Judde, Olivier Déas
Publikováno v:
Cancer Research. 83:4677-4677
Despite considerable progress in understanding the biology and genetics of breast cancer, the development of effective therapies needs physiological and predictive preclinical models. In this context, breast cancer (BC) patient-derived xenograft (PDX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff8fa5d90b86a523512a70b2a1d40d0b
https://doi.org/10.1158/1538-7445.am2023-4677
https://doi.org/10.1158/1538-7445.am2023-4677