Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jean-Francois Peyronel"'
Autor:
Corinne Lafon, Amélie Dommergue, Thomas Rooney, Dominique Lesuisse, Thy Phuong Hieu Luc, Anne Olivier, Pierre-Yves Abecassis, Luc Even, Véronique Taupin, Patrick Lardenois, Xavier Vigé, Marie-Noëlle Castel, Florian Auger, Yannick Evanno, Andre Malanda, Marie-Claude Burgevin, Pascal Barneoud, Céline Cegarra, Antonio Almario, Joanna Tsi, Pascale Brunel, Jean-Francois Peyronel, Danielle De-Peretti
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:929-932
In the course of a programme aimed at identifying Nurr1/NOT agonists for potential treatment of Parkinson’s disease, a few hits from high throughput screening were identified and characterized. A combined optimization pointed to a very narrow and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da24f03facfdd36275110ac060ed5915
https://doi.org/10.1016/j.bmcl.2019.01.024
https://doi.org/10.1016/j.bmcl.2019.01.024
4,4-Diphenyl-7-perhydrothiapyrano[3,4-c]pyrrolone, a new series of substance P receptors antagonists
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:1591-1594
The synthesis of 4,4-Diphenyl-7-perhydrothiapyrano[3,4-c]pyrrolones, a new series of substance P antagonists with high affinity for rat and human NK1 receptors is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8b3fd17964f6a9efef243affbf1c122
https://doi.org/10.1016/0960-894x(95)00277-z
https://doi.org/10.1016/0960-894x(95)00277-z
Autor:
Jean-Francois Peyronel, Claudine M'Houmadi, Jean-Luc Malleron, Eric Bacque, Jean-Marc Paris, Pascal Desmazeau
Publikováno v:
Synthetic Communications. 25:2355-2371
The syntheses of some new derivatives of 4, 4-diphenyl-2-cyclohexen-one are reported. In particular, we described a palladium-based strategy for the preparation of dienes (1) and (2).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ab532560a3a573058e78271ed4b4a10
https://doi.org/10.1080/00397919508015439
https://doi.org/10.1080/00397919508015439
Autor:
Jean-Luc Malleron, Jean-Francois Peyronel, Pascal Desmazeau, Claude Planiol, Claudine M'Houmadi
Publikováno v:
Tetrahedron Letters. 36:543-546
The reaction of the 5-mesylate derivative 7 in basic medium respectively gives in the absence of air, 2-t-butyloxycarbonyl-4,4-diphenyl-6-(2-methoxy-benzoyl) perhydrocyclopenta[c]pyrrole and in the presence of air, 2-t-butyloxycarbonyl-6,6-diphenyl-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39a408d67ddfc64559627aa8a8938615
https://doi.org/10.1016/0040-4039(94)02336-a
https://doi.org/10.1016/0040-4039(94)02336-a
Publikováno v:
Tetrahedron. 50:189-198
Chiral azomethine ylides, easily generated from 2-(tert-butyl)-3-methylimidazolidin-4-one and aldehydes, undergo 1,3-dipolar cycloadditions to activated alkenes. These reactions proceed with complete facial stereoselection. In the case of benzaldehyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc8ddd5c9a7e6e1a575f4929f920c9f8
https://doi.org/10.1016/s0040-4020(01)80744-4
https://doi.org/10.1016/s0040-4020(01)80744-4
Autor:
Jean-Francois Peyronel, M. Tabart
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:673-676
The synthesis of enentiomerically pure RPR 100893, a novel non peptide NK1 Substance P antagonist, is described. This compound is a representative of 7,7,4-triaryl perhydroisoindol-4-ols, a new series of perhydroisoindole Substance P antagonists with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70decff0db63afce379428457f9b8579
https://doi.org/10.1016/s0960-894x(01)80178-5
https://doi.org/10.1016/s0960-894x(01)80178-5
Publikováno v:
Synlett. 2002:0829-0831
A simple preparation of N-substituted 3-pyrroline boromic esters from primary amines is described. The Suzuki-Miyaura coupling of these heterocycles with aryl halides proceeds in good yields. Alternatively, oxidation withDDQ or MnO 2 gives the corres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75a143fc8b8246f03edea346bafe5052
https://doi.org/10.1055/s-2002-25351
https://doi.org/10.1055/s-2002-25351
Autor:
Francois Montier, Veronique Fardin, Jean-Francois Peyronel, Saliha Moussaoui, P.M. Laduron, A. Carruette, Claude Garret
Publikováno v:
Regulatory Peptides. 46:24-30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d890205aad6fc63cd7c499f9aad0a760
https://doi.org/10.1016/0167-0115(93)90007-u
https://doi.org/10.1016/0167-0115(93)90007-u
Autor:
Serge Mignani, P.M. Laduron, A. Doble, C. Gueremy, Zundel Jl, O. Piot, Alain Truchon, Jean-Charles Blanchard, Jean-Francois Peyronel, Jean-Luc Malleron
Publikováno v:
Journal of Medicinal Chemistry. 36:1194-1202
A series of new indole derivatives (2-28) has been prepared in the search for novel 5-HT uptake inhibitors. These compounds were obtained by the condensation of N-(chloroalkyl) naphthalenesultam derivatives with the appropriate amine in presence of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7382f57b351ab18b326b12b74e1ea978
https://doi.org/10.1021/jm00061a010
https://doi.org/10.1021/jm00061a010
Autor:
Jean-Charles Blanchard, B. Martin, Jean-Francois Peyronel, Alain Truchon, P. Mouton, Jean-Luc Malleron, A. Viroulaud, C. Gueremy, D. Allam, O. Piot, Zundel Jl, J. Betschart, C. Huon, M.‐T. Comte, A. Doble
Publikováno v:
ChemInform. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bbf813c3651e5468466391ed4c2ff3a
https://doi.org/10.1002/chin.199152223
https://doi.org/10.1002/chin.199152223