Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jean-Francois Cloutier"'
Autor:
Platon Megagiannis, Yuan Mei, Rachel E. Yan, Lin Yuan, Jonathan J. Wilde, Hailey Eckersberg, Rahul Suresh, Xinzhu Tan, Hong Chen, W. Todd Farmer, Kuwook Cha, Phuong Uyen Le, Helene Catoire, Daniel Rochefort, Tony Kwan, Brian A. Yee, Patrick Dion, Arjun Krishnaswamy, Jean-Francois Cloutier, Stefano Stifani, Kevin Petrecca, Gene W. Yeo, Keith K. Murai, Guoping Feng, Guy A. Rouleau, Trey Ideker, Neville E. Sanjana, Yang Zhou
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114637- (2024)
Summary: Reactive changes of glial cells during neuroinflammation impact brain disorders and disease progression. Elucidating the mechanisms that control reactive gliosis may help us to understand brain pathophysiology and improve outcomes. Here, we
Externí odkaz:
https://doaj.org/article/85d2608293c54038ac6d9ed11c01f673
Autor:
Jenea M. Bin, Dong Han, Karen Lai Wing Sun, Louis-Philippe Croteau, Emilie Dumontier, Jean-Francois Cloutier, Artur Kania, Timothy E. Kennedy
Publikováno v:
Cell Reports, Vol 12, Iss 7, Pp 1099-1106 (2015)
Netrin-1 regulates cell migration and adhesion during the development of the nervous system, vasculature, lung, pancreas, muscle, and mammary gland. It is also proposed to function as a dependence ligand that inhibits apoptosis; however, studies disa
Externí odkaz:
https://doaj.org/article/393a5f5c8e1b4c6489b5396050cb91a4
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Five decades ago, long-term potentiation (LTP) of synaptic transmission was discovered at entorhinal cortex→dentate gyrus (EC→DG) synapses, but the molecular determinants of EC→DG LTP remain largely unknown. Here, we show that the presynaptic n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423906e0ba4605e74328c3a50448444c
https://doi.org/10.1073/pnas.2123421119
https://doi.org/10.1073/pnas.2123421119
Autor:
Xue Fan Wang, Robin Vigouroux, Michal Syonov, Yuriy Baglaenko, Angeliki M. Nikolakopoulou, Dene Ringuette, Horea Rus, Peter V. DiStefano, Suzie Dufour, Alireza P. Shabanzadeh, Seunggi Lee, Bernhard K. Mueller, Jason Charish, Hidekiyo Harada, Jason E. Fish, Joan Wither, Thomas Wälchli, Jean-François Cloutier, Berislav V. Zlokovic, Peter L. Carlen, Philippe P. Monnier
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Liver failure causes breakdown of the Blood CNS Barrier (BCB) leading to damages of the Central-Nervous-System (CNS), however the mechanisms whereby the liver influences BCB-integrity remain elusive. One possibility is that the liver secrete
Externí odkaz:
https://doaj.org/article/863ced8c4fb94a3aaaf67d19e08288c8
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
The formation of complex structures, such as the craniofacial skeleton, requires precise and intricate two-way signalling between populations of cells of different embryonic origins. For example, the lower jaw, or mandible, arises from cranial neural
Externí odkaz:
https://doaj.org/article/603314da9c5d47b09979004e3a7d799a
Publikováno v:
2015 IEEE International Symposium on Technologies for Homeland Security (HST).
In the aftermath of Hurricane Sandy, the Multi-State Fleet Response Working Group (FWG) was established at the recommendation of the All Hazards Consortium (AHC) as an independent entity guided by private sector representatives from multiple sectors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc7357578c96464fda7fa2cb6a4d407d
https://doi.org/10.1109/ths.2015.7225281
https://doi.org/10.1109/ths.2015.7225281
Autor:
Viengsai Vongchampa, Min Dong, Jean Francois Cloutier, Timothy O’Connor, Lakshmaiah Gingipalli, Yoke W. Kow, Peter C. Dedon
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 594:120-134
Chronic inflammation is associated with a variety of human diseases, including cancer, with one possible mechanistic link involving over-production of nitric oxide (NO*) by activated macrophages. Subsequent reaction of NO* with superoxide in the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec4608849e2e3e3641340269d7b3f49
https://doi.org/10.1016/j.mrfmmm.2005.08.008
https://doi.org/10.1016/j.mrfmmm.2005.08.008
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Differential expression of cell adhesion molecules in neuronal populations is one of the many mechanisms promoting the formation of functional neural circuits in the developing nervous system. The IgLON family consists of five cell surface i
Externí odkaz:
https://doaj.org/article/385c10597efb4de58484bf1fc274648f
Publikováno v:
2011 IEEE International Conference on Technologies for Homeland Security (HST).
In order to manage security and disaster risk, government agencies and their partners need to share information. Having the tools and networks needed to transmit and receive information is vital, but even with these systems in place, information does
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c0acf88223989dafa4366b1e92ea393
https://doi.org/10.1109/ths.2011.6107864
https://doi.org/10.1109/ths.2011.6107864
Autor:
Yelena Margolin, Peter C. Dedon, Nicholas E. Geacintov, Vladimir Shafirovich, Jean Francois Cloutier
Publikováno v:
Nature chemical biology. 2(7)
Guanine in DNA is a major oxidation target owing to its low ionization potential (IP), and there is often an inverse correlation between damage frequency and sequence-dependent variation in guanine IP. We report that the biological oxidant nitrosoper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cdc9309a158fd2f07e982f9a2c978ef
https://pubmed.ncbi.nlm.nih.gov/16783334
https://pubmed.ncbi.nlm.nih.gov/16783334